Automatic gain control and method for enabling detection of low and high amplitude depolarization activation waves of the heart and atrial defibrillator utilizing the same

• US 5,458,621 A
• Filed: 03/15/1994
• Issued: 10/17/1995
• Est. Priority Date: 03/15/1994
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: InControl, Inc. (Daikin Industries Ltd)
• Inventors: Bocek, Joseph M., White, Harley
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Parker, Marianne
• Application Number:
  US08/213,119
• Time in Patent Office: 581 Days
• Field of Search: 128/700, 128/702, 128/705, 128/708, 607/4, 607/5, 607/28
• US Class Current: 607/5
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation

Abstract

An apparatus reliably detects a depolarization activation wave of the heart. The apparatus includes a sensor in electrical contact with the heart for sensing electrical activity of the heart and including an amplifier for amplifying the sensed electrical activity according to a variable gain and providing a signal corresponding to the depolarization activation wave. The apparatus further includes an output circuit coupled to the sensor for producing an electrical output corresponding to the depolarization activation wave sensed by the sensor when the signal exceeds a threshold. The apparatus still further includes a control circuit coupled to the sensor and the output circuit for varying at least one of the gain and the threshold to maintain a predetermined sense margin between the sensed electrical activity and the gain and the threshold.

Claims

1. A method for reliably detecting a depolarization activation wave of a heart, the method including the steps of:

providing a detection system having a gain and a threshold;

sensing activity of the heart in at least one chamber of the heart and producing an input signal corresponding to said sensed activity, said input signal having an input amplitude;

amplifying said input signal according to said gain to produce an amplified input signal having an amplified input amplitude;

producing an output when said amplified input signal exceeds said threshold, said output indicating an occurrence of said depolarization activation wave; and

varying at least one of said gain and said threshold to maintain a predetermined sense margin between said input amplitude and said gain and said threshold.

2. A method as defined in claim 1 further including the steps of:

sensing said activity of the heart during a predetermined time duration;

determining a plurality of peak deviations of said amplified input amplitude from a predetermined baseline during said predetermined time duration;

determining a reference sense margin from said plurality of peak deviations; and

determining said sense margin from a ratio of said reference sense margin to said threshold.

3. A method as defined in claim 2 further including the steps of dividing said predetermined time duration into a plurality of time segments and determining a peak deviation of said amplified input amplitude from said predetermined baseline during each time segment of said plurality of time segments to form said plurality of peak deviations.

4. A method as defined in claim 3 further including the step of averaging a predetermined number of peak deviations of said plurality of peak deviations to determine said reference sense margin.

5. A method as defined in claim 4 further including the step of averaging a least one of a first peak deviation determined during a first time segment and a second peak deviation determined during a second time segment and a least one of a third peak deviation determined during a third time segment and a fourth peak deviation determined during a fourth time segment to determine said reference sense margin.

6. An apparatus for reliably detecting a depolarization activation wave of a heart, the apparatus comprising:

sensing means in electrical contact with the heart for sensing electrical activity of the heart and including amplifying means for amplifying said sensed electrical activity by a gain and providing a signal;

threshold means coupled to said amplifying means for producing an electrical output when said signal exceeds a threshold; and

control means coupled to said sensing means and said threshold means for varying at least one of said gain and said threshold to maintain a predetermined sense margin between said sensed electrical activity and said gain and said threshold.

7. An apparatus as defined in claim 6 further comprising conversion means coupled to said sensing means for converting said signal to digital data and memory means for storing said digital data during a predetermined time duration.

8. An apparatus as defined in claim 7 wherein said control means is coupled to said storage means for receiving said stored digital data and wherein said control means varies said gain and said threshold in response to said digital data.

9. An apparatus as defined in claim 8 wherein said control means includes processing means for determining a plurality of peak values of said digital data during said predetermined time duration and averages a predetermined number of said plurality of peak values to determine a sense margin reference level, said control means varying at least one of said gain and said threshold in response to said sense margin reference level.

10. An apparatus as defined in claim 9 wherein said processing means determines said sense margin from a ratio of said sense margin reference level and said threshold.

11. An implantable atrial defibrillator for applying cardioverting electrical energy to the atria of a heart in synchronism with a detected depolarization activation wave, the atrial defibrillator comprising:

detecting means for sensing activity of the heart in at least one of the atria of the heart;

atrial fibrillation detecting means responsive to activity of the heart sensed by said detecting means for determining when the atria of the heart are in need of cardioversion;

an apparatus for detecting a depolarization activation wave of the heart, said apparatus including sensing means in electrical contact with the heart for sensing electrical activity of the heart and including amplifying means for amplifying said sensed electrical activity by a gain and providing a signal, threshold means coupled to said amplifying means for producing an electrical output when said signal exceeds a threshold, and control means coupled to said sensing means and said threshold means for varying at least one of said gain and said threshold to maintain a predetermined sense margin between said sensed electrical activity and said gain and said threshold; and

cardioverting means for applying cardioverting electrical energy to the atria of the heart when the atria of the heart are in need of cardioversion and responsive to said electrical output.

12. An atrial defibrillator as defined in claim further comprising conversion means coupled to said sensing means for converting said signal to digital data and memory means for storing said data.

13. An atrial defibrillator as defined in claim 12 wherein said control means includes processing means coupled to said storage means for receiving said data and determining a peak value of said data for each time segment of a predetermined number of time segments to form a plurality of peak values, said control means varying at least one of said gain and said threshold in response to said plurality of peak values.

14. An atrial defibrillator as defined in claim 13 wherein said processing means averages a predetermined number of peak values of said plurality of peak values to determine a sense margin reference level, and wherein said processing means determines said sense margin from a ratio of said sense margin reference level and said threshold.

15. An atrial defibrillator as defined in claim 14 wherein said processing means determines a first peak value during a first time segment, a second peak value during a second time segment, a third peak value during a third time segment and a fourth peak value during a fourth time segment and wherein said processing means averages a least one of said first peak value and said second peak value and a least one of said third peak value and said fourth peak value to determine said sense margin reference level.

16. An atrial defibrillator as defined in claim 15 wherein said control means varies at least one of said gain and said threshold to maintain said ratio substantially equal to a predetermined number.

17. An atrial defibrillator as defined in claim 16 wherein said control means maintains said ratio substantially equal to 2.