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Lipophilic, aminohydrolase-activated prodrugs

  • US 5,459,256 A
  • Filed: 04/10/1991
  • Issued: 10/17/1995
  • Est. Priority Date: 04/17/1987
  • Status: Expired due to Term
First Claim
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1. A compound of the formula:

  • ##STR10## wherein A is F;

    B is H;

    Y is H or NH2 ; and

    X is selected from the group consisting of halogen, NHR or OR, whereinR is C1-8 alkyl, straight chain or branched chain, and NROR, wherein Ris H or C1-8 alkyl, straight chain or branched chain.

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