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Device and method for analysis of blood components and identifying inhibitors and promoters of the inflammatory response

  • US 5,460,945 A
  • Filed: 05/20/1992
  • Issued: 10/24/1995
  • Est. Priority Date: 05/30/1991
  • Status: Expired due to Term
First Claim
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1. An apparatus comprising (a) a solid phase having at least one surface containing a plurality of one or more substantially purified molecules, said molecules being capable of mediating rolling of a leukocyte on the solid phase surface;

  • (b) a housing enclosing the solid phase, said housing having an inlet end and an outlet end for respectively receiving and removing a sample containing or suspected of containing leukocytes;

    (c) a means associated with the inlet for introducing said sample into the housing; and

    (d) a means associated with the outlet for withdrawing said sample from the housing, said apparatus being capable of permitting detection of leukocyte rolling on the solid phase surface.

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