Apparatus and method for use in measuring a compositional parameter of blood

• US 5,462,052 A
• Filed: 04/27/1993
• Issued: 10/31/1995
• Est. Priority Date: 01/30/1987
• Status: Expired due to Fees

• Current Assignee: Terumo Cardiovascular Systems Corporation (Terumo Corporation)
• Original Assignee: Minnesota Mining and Manufacturing Co (3M Company)
• Inventors: Maxwell, Thomas P., Holody, Mark Z., Hacker, Thomas G., Gehrich, John L.
• Primary Examiner(s): Redding, David A.
• Application Number:
  US08/055,800
• Time in Patent Office: 917 Days
• Field of Search: 422/58, 422/68.1, 422/81, 422/82.04-82.11, 422/82.05, 436/56, 436/68, 436/138, 436/163, 128/632, 128/633, 128/636, 128/637, 128/665, 604/4-6
• US Class Current: 600/323
• CPC Class Codes: A61B 5/02158 provided with two or more sensor elements
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence

Abstract

A sensor cassette for use in measuring a compositional parameter of blood comprising a housing having a wall defining a passage which is adapted to receive blood. The wall is at least somewhat permeable to the compositional parameter. A support element, which is less permeable to the compositional parameter of blood than the housing, is carried by a region of the wall. A sensor is carried by the support element and provides a signal in response to the compositional parameter. The support element separates the sensor from at least a portion of such region of the wall so that the affect of the permeability of the housing to the compositional parameter on the signal from the sensor is reduced.

Claims

1. A sensor cassette for use in measuring a compositional parameter of blood comprising:

a housing having a wall defining a passage which is adapted to receive blood, said wall being at least somewhat permeable to the compositional parameter of blood;

a support element carried by a region of said wall;

said support element being less permeable to the compositional parameter of blood than said housing;

a sensor carried by the support element, said sensor providing a signal in response to the compositional parameter of blood; and

said support element separating the sensor from at least a portion of said region of the wall whereby the effect of the permeability of the housing to the compositional parameter of blood on said signal is reduced.

2. A sensor cassette as defined in claim 1 wherein said wall includes polymeric material which is at least somewhat permeable to the compositional parameter of blood.

3. A sensor cassette as defined in claim 2 wherein the polymeric material includes polycarbonate, said compositional parameter of blood is blood gas and said sensor provides said signal in response to blood gas.

4. A sensor cassette as defined in claim 1 wherein said compositional parameter of blood is blood gas and said sensor provides said signal in response to the partial pressure of the blood gas.

5. A sensor cassette as defined in claim 2 wherein the polymeric material includes polycarbonate and the support element is constructed of glass.

6. A sensor cassette as defined in claim 1 wherein said wall has a cavity therein and the support element is in said cavity.

7. A sensor cassette as defined in claim 6 wherein the support element terminates outwardly in a support surface and the sensor is carried on the support surface.

8. A sensor cassette as defined in claim 7 wherein the support surface is outside the cavity.

9. A sensor cassette as defined in claim 7 including a gas permeable overcoat on the sensor, said sensor and overcoat being received in the cavity.

10. A sensor cassette for use in measuring blood gas of blood from a patient comprising:

a housing of polymeric material having a wall defining a passage, said passage being adapted to receive blood;

a support element carried by a region of said wall;

said support element being substantially impermeable to blood gases; and

a sensor carried by the support element and physically separated from said region of said wall by said support element, said sensor being in a position to be contacted by blood gas from blood which is received in the passage, said sensor providing a signal in response to the concentration of blood gas.

11. A sensor cassette as defined in claim 10 wherein said wall has a cavity therein and the support element is in said cavity.

12. A sensor cassette as defined in claim 11 wherein the support element projects out of the cavity and terminates in a support surface which is outside the cavity and said sensor is on said support surface.

13. A sensor cassette as defined in claim 10 wherein the sensor is an optical sensor and the support element is substantially transparent.

14. A sensor cassette as defined in claim 10 wherein the support element is constructed of glass.

15. A sensor cassette for use in measuring blood gas of blood from a patient comprising:

a housing having a wall of polymeric material defining a passage, said passage being adapted to receive blood;

said wall having a cavity opening into said passage;

a support element in said cavity which is less permeable to blood gas than the polymeric material, said support element terminating outwardly in a support surface; and

a sensor carried by the support element on said support surface, said sensor being capable of providing a signal in response to the concentration of the blood gas.

16. A sensor cassette as defined in claim 15 wherein the support element is constructed of glass.

17. A sensor cassette as defined in claim 16 including a gas permeable overcoat on the sensor.

18. A sensor cassette as defined in claim 17 wherein the support surface is outside of the cavity and the sensor is a fluorescent sensor.

19. A sensor cassette as defined in claim 15 wherein the cavity does not extend all the way through said wall.

20. A sensor cassette for use in measuring blood gas of blood from a patient comprising:

a housing having a wall of a transparent polycarbonate material defining a passage, said passage being adapted to receive blood;

said wall having a cavity which does not extend all the way through the wall, said cavity opening into said passage;

a support element in said cavity which is less permeable to blood gas than the wall of polycarbonate material, said support element terminating outwardly in a support surface; and

a fluorescent sensor carried by the support element on said support surface, said sensor being capable of providing a fluorescent signal in response to the concentration of blend gas, and the support element being transparent to said fluorescent signal.