Microdelivery device and method for enhanced drug administration to the eye
First Claim
1. A device for pinpoint application of micro-quantities of a pharmaceutical composition to a preselected portion of the outer hard coat of the eye,the device comprising a micro-container with fixation means for reversible attachment of said micro-container to the outer hard coat of the eye adjacent to the preselected portion thereof,said micro-container comprising a pharmaceutical composition delivery bore whose aperture is adapted to contact the preselected portion of the outer hard coat of the eye so as to expose only the preselected portion thereof to the pharmaceutical composition.
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Accused Products
Abstract
A device for pinpoint application of micro-quantities of a pharmacologically suitable composition to the outer hard coat of the eye, comprises a micro-container with a fixation element. The micro-container comprises a bore whose aperture is adapted to contact the eye surface, and the fixation element is adapted for reversibly adhering to the eye surface.
106 Citations
10 Claims
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1. A device for pinpoint application of micro-quantities of a pharmaceutical composition to a preselected portion of the outer hard coat of the eye,
the device comprising a micro-container with fixation means for reversible attachment of said micro-container to the outer hard coat of the eye adjacent to the preselected portion thereof, said micro-container comprising a pharmaceutical composition delivery bore whose aperture is adapted to contact the preselected portion of the outer hard coat of the eye so as to expose only the preselected portion thereof to the pharmaceutical composition.
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8. A non-invasive method for applying pharmaceutical compositions to a preselected portion of the outer hard coat of an eye at pinpoint locations, comprising the following steps:
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providing a micro-container containing an amount of a pharmaceutical composition and having a pharmaceutical composition delivery bore; and reversibly attaching the micro-container to the outer hard coat of the eye so as to locate the delivery bore in contact with said preselected portion and thereby deliver the pharmaceutical composition solely to said preselected portion. - View Dependent Claims (9)
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10. A method for treating glaucoma, comprising administering, at pinpoint location on the limbus of the eye for a given time, a sufficient amount of collagenase composition to effect limited controlled tissue degradation, thereafter neutralizing the collagenase and rinsing the eye, thereby decreasing the intraocular pressure.
Specification