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Bioadhesive pharmaceutical carrier

  • US 5,462,749 A
  • Filed: 04/26/1994
  • Issued: 10/31/1995
  • Est. Priority Date: 09/25/1991
  • Status: Expired due to Term
First Claim
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1. A bioadhesive pharmaceutical gel, consisting essentially of:

  • a therapeutically effective amount of an antidepressant agent;

    about 0.25 to about 25 percent by weight sodium carboxy-methyl cellulose;

    about 0.25 to about 25 percent by weight xanthan gum or sodium alginate and;

    diluent selected from the group consisting of glycerin, propylene glycol, dioxolanes, glycerol, glycofurol, dimethylacetamide, ethyl lactate, alcohols, glycols, sorbitols, USP oils, NF oils, lecithin, lanolin, ethyl oleate, isopropyl myristate, benzyl benzoate, petrolatum, cocoa butter and mixtures thereof.

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