Gold coating means for limiting thromboses in implantable grafts

• US 5,464,438 A
• Filed: 05/03/1993
• Issued: 11/07/1995
• Est. Priority Date: 10/05/1988
• Status: Expired due to Fees

• Current Assignee: Gerald J. Menaker
• Original Assignee: Gerald J. Menaker
• Inventors: Menaker, Gerald J.
• Primary Examiner(s): Prebilic, Paul B.
• Application Number:
  US08/057,341
• Time in Patent Office: 918 Days
• Field of Search: 623/1, 623/2, 623/11, 623/12, 600/37, 604/266
• US Class Current: 623/1.43
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2310/00568 Coating made of gold or Au-based alloys
• CPC Class Codes: A61F 2310/00928 Coating or prosthesis-covering structure made of glass or of glass-containing compounds, e.g. of bioglass
• CPC Class Codes: A61L 27/306 Other specific inorganic materials not covered by A61L27/303 - A61L27/32
• CPC Class Codes: A61L 27/507 for artificial blood vessels apparatus for applying cells on a blood vessel prosthesis A61F2/062
• CPC Class Codes: A61L 31/088 Other specific inorganic materials not covered by A61L31/084 or A61L31/086
• CPC Class Codes: A61L 33/022 Metal or alloys

Abstract

Vascular grafts, shunts, patches or valves are formed of material tolerated by the body and are lined or coated with gold to form a non-thrombogenic surface. Methods of manufacture are also disclosed.

Claims

1. In an implantable device for use as a component in the blood circulatory system of a living recipient, said device formed from a fabric of a synthetic material, said fabric characterized by interstices created by the nature of the manufacturing of the fabric, said device having a surface formed by said fabric, said surface for exposure to the blood of said recipient, the improvement comprising:

a thin layer of metallic gold applied to coat said fabric forming said surface,

said layer applied to leave said interstices open and unblocked.

2. The construction of claim 1 wherein said implantable device is a vascular shunt or graft comprising:

a tubular body, formed from said fabric,

said tubular body having an inner wall; and

said layer of metallic gold applied to said inner wall.

3. The construction of claim 1 wherein said implantable device is a vascular patching device, said patching device comprising:

a backing formed from said fabric; and

said layer of metallic gold applied to at least one side of said backing.

4. The construction of claim 1, wherein said implantable device is an artificial heart valve assembly,

said assembly including a suture cuff formed from said fabric;

and

said layer of metallic gold applied to said suture cuff.

5. The construction of claims 2, 3 or 4 wherein said layer of metallic gold is vapor-deposited onto said fabric.

6. The construction of claims 2, 3 or 4 wherein said layer of metallic gold is sputtered onto said fabric.

7. The construction of claims 2, 3 or 4 wherein said layer of metallic gold is vacuum-deposited onto said fabric.

8. The construction of claim 1 wherein said fabric is tetrafluoroethylene polymer.

9. The construction of claim 1 wherein said fabric is polyethylene glycol terephthalate.

10. The construction of claim 1 wherein said fabric is expanded microporous polytetrafluoroethylene.