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Methods of normalizing metabolic parameters in diabetics

  • US 5,468,727 A
  • Filed: 02/16/1993
  • Issued: 11/21/1995
  • Est. Priority Date: 12/13/1990
  • Status: Expired due to Term
First Claim
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1. A method of maintaining the following glucose metabolic indicators at or near normal levels;

  • blood glucose, C-peptide and insulin levels at fasting and during oral glucose tolerance tests, hemoglobin A1C, insulin sensitivity and GIP levels in a human having a early non-insulin dependent diabetic condition and exhibiting rapid grastric emptying, comprising administering to said individual a therapeutically effective dose of POT II, cholecystokinin, cholestyramine or camostat to effectively raise plasma cholecystokinin levels to about 2-3 fold of basal fasting levels of cholecystokinin in said human.

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