Analytical system useful in diagnosis of the condition of a disease

• US 5,470,534 A
• Filed: 05/02/1994
• Issued: 11/28/1995
• Est. Priority Date: 05/10/1993
• Status: Expired due to Term

• Current Assignee: Hitachi, Ltd.
• Original Assignee: Hitachi, Ltd.
• Inventors: Imai, Kazumichi, Nomura, Yasushi, Imai, Kyoko
• Primary Examiner(s): Housel, James C.
• Assistant Examiner(s): Le, Long V.
• Application Number:
  US08/236,134
• Time in Patent Office: 575 Days
• Field of Search: 422/63, 422/64, 422/65, 422/67, 422/68.1, 422/105, 422/70, 422/73, 436/43, 436/47, 436/50, 436/55, 436/180, 436/48
• US Class Current: 422/67
• CPC Class Codes: G01N 35/00603 Reinspection of samples
• CPC Class Codes: G01N 35/0092 Scheduling
• CPC Class Codes: G01N 35/025 having a carousel or turntable for reaction cells or cuvettes
• CPC Class Codes: Y10T 436/11 Automated chemical analysis
• CPC Class Codes: Y10T 436/113332 with conveyance of sample along a test line in a container or rack
• CPC Class Codes: Y10T 436/114165 with step of insertion or removal from test line
• CPC Class Codes: Y10T 436/115831 Condition or time responsive
• CPC Class Codes: Y10T 436/12 Condition responsive control

Abstract

In a first measurement stage, reaction solutions of samples are optically measured by a biochemical analyzer, and the measurement result of the analysis item which is an index of the disease status regarding the samples is compared with the check index. This check index is stored in memory beforehand. When the measurement result corresponds to the check index, the sample processing goes to a second measurement stage for measuring a specific item. In the second measurement stage, the sample is measured by an immuno-assay apparatus or a nucleic acid analyzer, and the measurement result is outputted.

Claims

1. An analytical system for analyzing a biological sample which is gathered from a patient once, the system comprising:

means for storing an index analysis item of the biological sample to be measured in a first measurement stage, an assay item of the biological sample to be optionally measured in a second measurement stage following said first measurement stage, and a check level;

means for measuring the index analysis item of the biological sample in the first measurement stage;

determining means for determining whether to measure the assay item of the biological sample in the second measurement stage, which is different from the index analysis item of the first measurement stage, on the basis of a comparison of data of the measured index analysis item with the check level;

means for measuring the assay item of the biological sample in the second measurement stage responsive to said determining means determining that the assay item should be measured; and

means for outputting data of the measured assay item.

2. An analytical system according to claim 1, wherein said output means includes display means for displaying the index analysis item of the biological sample to be measured in the first measurement stage, the assay item of the biological sample to be measured in the second measurement stage, and an appropriate value providing a criterion for said determining means to employ in determining whether to measure the assay item of the biological sample on the basis of results of the comparison employed by said determining means.

3. An analytical system according to claim 2, further comprising input means for inputting the appropriate value.

4. An analytical system according to claim 3, wherein said input means selects an assay device for carrying out a measurement operation of the assay item in the second measurement stage.

5. An analytical system according to claim 1, wherein said means for measuring the index analysis item is a biochemical assay device, and said means for measuring said assay item is an immuno-assay device or a nucleic acid assay device, said system further comprising a sample supplier which is shared by said means for measuring said index analysis item and said means for measuring said assay item.

6. An analytical system according to claim 1, wherein said means for measuring said assay item is a chromatographic assay device.

7. An analytical system according to claim 1, wherein said output means outputs the measured result of the assay item as well as the measured result of the index analysis item.

8. An analytical system for analyzing a biological sample which is gathered from a patient once, the system comprising:

biochemical analysis means and immuno-assay means for measuring analysis items of the biological sample, wherein the biochemical analysis means measures GOT and GPT as first analysis items of the biological sample in a first measurement stage;

means for storing a plurality of check indexes for finding a possibility of a disease regarding GOT and GPT;

means for determining which of the plurality of check indexes corresponds to measured results of at least one of the GOT and GPT of the biological sample, and for determining for measurement in a second measurement stage at least one of the analysis items that corresponds to the determined check index, said at least one of the analysis items being different from said first analysis items; and

control means for controlling an operation of the biochemical analysis means or the immuno-assay means so as to measure at least one of the analysis items which is determined to correspond to the determined check index in said second measurement stage.

9. An analytical system according to claim 8, wherein said control means controls an operation of the immuno-assay means when both the measurement results of GOT and GPT of a sample correspond to individual ones of the check indexes.