Ultrasonic diagnosis and therapy system in which focusing point of therapeutic ultrasonic wave is locked at predetermined position within observation ultrasonic scanning range

• US 5,471,988 A
• Filed: 12/23/1994
• Issued: 12/05/1995
• Est. Priority Date: 12/24/1993
• Status: Expired due to Term

• Current Assignee: Olympus Optical Corporation Limited (Olympus Corporation)
• Original Assignee: Olympus Optical Corporation Limited (Olympus Corporation)
• Inventors: Ueda, Yasuhiro, Takehana, Sakae, Hirao, Isami, Oaki, Yoshinao, Kuramoto, Seiji, Fujio, Kouji, Tsukaya, Takashi
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US08/363,621
• Time in Patent Office: 347 Days
• Field of Search: 128/660.03, 128/660.08, 128/660.09, 128/660.10, 128/661.01, 128/662.03, 128/662.06, 128/663.01, 128/665, 128/4, 128/6, 607/88, 607/92, 607/96, 607/97
• US Class Current: 600/439
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 2017/00924 for ultrasonic waves
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/4272 involving the acoustic interface between the transducer and the tissue
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 90/36 Image-producing devices or illumination devices not otherwise provided for
• CPC Class Codes: A61B 90/80 Implements for cleaning or washing the skin of surgeons or patients

Abstract

Provided on the side of a distal end of an insertion part are an observation ultrasonic transducer for acquiring an ultrasonic image and a therapeutic ultrasonic transducer for outputting a therapeutic ultrasonic wave so as to be focused. Positioning or the like between the observation ultrasonic transducer and the therapeutic ultrasonic transducer is so conducted that a focusing point at which the therapeutic ultrasonic wave is focused is locked to a predetermined position within a scanning range of the observation ultrasonic wave. If the position of the focusing point is locked whereby a lesion part to be treated is set to a predetermined position on an ultrasonic image, it is necessarily possible to conduct the position setting to the focusing point. It is also made possible to confirm the position of the lesion part and to acoustically observe a state of the lesion part during irradiation of the therapeutic ultrasonic wave.

Claims

1. An ultrasonic diagnosis and therapy system comprising:

ultrasonic observation and therapy means provided with an observation ultrasonic transducer for transmitting and receiving an observation ultrasonic wave in order to acquire an ultrasonic image and a therapeutic ultrasonic transducer for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part so as to be focused, on the side of a distal end of an elongated insertion part capable of being inserted into a coelom;

signal processing means for conducting signal processing which generates a signal driving said observation ultrasonic transducer and which generates an image signal from an ultrasonic signal which is received by said observation ultrasonic transducer;

drive means for driving said therapeutic ultrasonic transducer to generate a drive signal for generating a therapeutic ultrasonic wave;

display means for inputting said image signal to thereby display said ultrasonic image corresponding to said image signal; and

scanning means for scanning said observation ultrasonic wave under a state in which a focusing point of said therapeutic ultrasonic wave is locked to a predetermined position within a scanning range of said observation ultrasonic wave.

2. A system according to claim 1, wherein said scanning means includes mechanical scanning means for rotating said observation ultrasonic transducer, for at least a predetermined angle which covers said scaning range, wherein said focusing point exists in an irradiation direction of said observation ultrasonic wave at a time said observation ultrasonic transducer is rotated through a certain angle.

3. A system according to claim 1, wherein said observation ultrasonic transducer is formed by a transducer array in which a plurality of ultrasonic transducers are arranged in the form of a belt along a single plane, wherein said scanning means includes electronic scanning means which electrically drives said transducer array in changing of timing, and wherein said scanning range including a direction to which said focusing point belongs is scanned with said observation ultrasonic wave by said electronic scanning means.

4. A system according to claim 3, wherein said single plane is a planar plane, and wherein said electronic scanning means electrically drives the plurality of ultrasonic transducers in changing of timing, whereby said scanning range including the direction to which said focusing point belongs is scanned by said observation ultrasonic wave.

5. A system according to claim 3, wherein said single plane is a cylindrical face, and wherein said electronic scanning means successively drives each of said ultrasonic transducers electrically, whereby scanning is made radially in each of directions corresponding to said scanning range including a direction to which said focusing point belongs, by said observation ultrasonic wave.

6. A system according to claim 3, wherein setting is made such that said focusing point exists in a radial direction of an outputting face which outputs the ultrasonic wave, of at least one of said plurality of ultrasonic transducers.

7. A system according to claim 1, wherein said focusing point is set so as to reside on a two equally divided line which substantially divides the scanning range in two.

8. A system according to claim 1, further comprising marker display means for displaying a marker at a position which corresponds to said focusing point, on an image of said ultrasonic signal.

9. A system according to claim 1, wherein said therapeutic ultrasonic transducer has a concave-shaped outputting face which outputs the ultrasonic wave to output the focused therapeutic ultrasonic wave from said outputting face.

10. A system according to claim 1, wherein manipulation of transmission and receiving of said observation ultrasonic wave is possible in parallel with manipulation which irradiates said therapeutic ultrasonic wave to said focusing point.

11. A system according to claim 1, wherein said observation ultrasonic transducer and said therapeutic ultrasonic transducer are driven by respective frequencies which are different from each other.

12. A system according to claim 1, wherein said observation ultrasonic transducer and said therapeutic ultrasonic transducer are driven by respective frequencies thereof which are different from each other, of 2 to 12 MHz.

13. A system according to claim 1, wherein said therapeutic ultrasonic transducer includes a plurality of ultrasonic transducers which are different in distance to the focusing point from each other, and wherein the system further comprises selection means for selecting the used ultrasonic transducers.

14. A system according to claim 1, wherein said therapeutic ultrasonic transducer includes distance modification means for modifying a distance to the focusing point.

15. A system according to claim 1, wherein said scanning means includes therapeutic ultrasonic scanning means for scanning the therapeutic ultrasonic wave.

16. A system according to claim 1, wherein said display means includes head mount displays having respective display faces thereof in front of eyes of an operator.

17. A system according to claim 1, further comprising an X-ray CT device for displaying a tomographic image due to an X-ray.

18. A system according to claim 1, further comprising an MRI device for displaying a tomographic image which utilizes nuclear magnetic resonance.

19. An ultrasonic probe comprising:

an elongated insertion part insertable into a coelom;

a first therapeutic ultrasonic transducer arranged on the side of a distal end of said insertion part, for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part, so as to be focused;

an observation ultrasonic transducer arranged on the side of the distal end of said insertion part, for transmitting and receiving an observation ultrasonic wave over a scanning range which is set in order to acquire an ultrasonic image; and

lock means for locking a focusing point of said therapeutic ultrasonic wave to a predetermined position in said scanning range.

20. An ultrasonic probe according to claim 19, further comprising a bendable curvature part at the side of the distal end of said insertion part.

21. An ultrasonic probe according to claim 19, wherein a curvature part is provided closer to the rear of the insertion part than said therapeutic ultrasonic transducer and said observation ultrasonic transducer.

22. An ultrasonic probe according to claim 19, further comprising optically observing optical observation means on the side of the distal end of said insertion part.

23. An ultrasonic probe according to claim 22, wherein said optical observation means is provided closer to the rear of the insertion part than said first therapeutic ultrasonic transducer and said observation ultrasonic transducer.

24. An ultrasonic probe according to claim 22, wherein said optical observation means is of a strabismus type whose observation direction is a slant forward direction.

25. An ultrasonic probe according to claim 19, wherein said insertion part includes a channel therein into which a treatment tool for conducting a treatment is insertable.

26. An ultrasonic probe according to claim 19, further comprising ultrasonic focusing means for focusing the ultrasonic wave outputted from said first therapeutic ultrasonic transducer through a predetermined distance.

27. An ultrasonic probe according to claim 26, wherein said ultrasonic focusing means is formed by one in which a face of said first therapeutic ultrasonic transducer, which outputs the ultrasonic wave, is formed substantially into a concave face.

28. An ultrasonic probe according to claim 19, wherein said first therapeutic ultrasonic transducer has an area outputting the ultrasonic wave, which is larger than that of said observation ultrasonic transducer.

29. An ultrasonic probe according to claim 19, further comprising scanning means for scanning the ultrasonic wave which is outputted from said observation ultrasonic transducer.

30. An ultrasonic probe according to claim 29, wherein said observation ultrasonic transducer has an ultrasonic transducer array in which a plurality of ultrasonic transducers are arranged, and wherein said scanning means has includes electronic scanning means for electronically driving said ultrasonic transducer array.

31. An ultrasonic probe according to claim 29, wherein said scanning means has mechanical scanning means for mechanically driving said observation ultrasonic transducer.

32. An ultrasonic probe according to claim 29, wherein said scanning means includes radial scanning means for scanning the ultrasonic wave which is outputted from said observation ultrasonic transducer, in a radial direction which is perpendicular to an axis of said insertion part.

33. An ultrasonic probe according to claim 29, wherein said scanning means includes linear scanning means for scanning the ultrasonic wave which is outputted from said observation ultrasonic transducer, in a plane which is parallel to an axis of said insertion part.

34. An ultrasonic probe according to claim 29, wherein said observation ultrasonic transducer includes an ultrasonic transducer array in which the plurality of ultrasonic transducers are arranged along a convex face, in a plane including an axis of said insertion part, and wherein said scanning means electronically drives said ultrasonic transducer array.

35. An ultrasonic probe according to claim 19, wherein said focusing point is set substantially to a center of said scanning range.

36. An ultrasonic probe according to claim 19, further comprising cooling means for cooling said first therapeutic ultrasonic transducer.

37. An ultrasonic probe according to claim 36, wherein said cooling means includes a line for supplying cooling liquid for cooling said first therapeutic ultrasonic transducer, to a location in the vicinity of said first therapeutic ultrasonic transducer.

38. An ultrasonic probe according to claim 19, further comprising temperature detection means for detecting temperature in the vicinity of said first therapeutic ultrasonic transducer.

39. An ultrasonic probe according to claim 19, further comprising a receiving coil which receivers a nuclear magnetic resonance signal which utilizes nuclear magnetic resonance, on the side of the distal end of said insertion part.

40. An ultrasonic probe according to claim 19, wherein said first therapeutic ultrasonic transducer is provided nearer the distal end of said insertion part than said observation ultrasonic transducer.

41. An ultrasonic probe according to claim 40, wherein said first therapeutic ultrasonic transducer is provided detachably at a position nearer the distal end of said insertion part than said observation ultrasonic transducer.

42. An ultrasonic probe according to claim 41, wherein a second therapeutic ultrasonic transducer which is different in characteristic from said first therapeutic ultrasonic transducer is capable of being detachably mounted on a position near the distal end of said insertion part.

43. An ultrasonic probe according to claim 19, wherein said first therapeutic ultrasonic transducer and said observation ultrasonic transducer have an integrated structure.

44. An ultrasonic probe according to claim 19, wherein said first therapeutic ultrasonic transducer and said observation ultrasonic transducer have structures formed at different positions by a common electric acoustic conversion element.

45. An ultrasonic probe according to claim 19, wherein said observation ultrasonic transducer is formed substantially at a center position of said electric acoustic conversion element.

46. An ultrasonic probe according to claim 19, wherein a balloon which receives an ultrasonic transfer medium is mounted at the periphery of a portion of said insertion part, in which said first therapeutic ultrasonic transducer and said observation ultrasonic transducer are built.

47. An ultrasonic probe according to claim 19, wherein said first therapeutic ultrasonic transducer has a plurality of ultrasonic transducers which are different from each other in distance to the focusing point.

48. An ultrasonic endoscope comprising:

an elongated insertion part insertable into a coelom;

an illumination optical system arranged on the side of a distal end of said insertion part, for outputting illumination light;

an observation optical system for optically observing an object which is illuminated by said illumination light;

an observation ultrasonic transducer arranged on the side of the distal end of said insertion part, for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image; and

a therapeutic ultrasonic transducer arranged on the side of the distal end of said insertion part, for irradiating, in focusing, an ultrasonic wave for conducting therapy with respect to an object part.

49. An ultrasonic diagnosis and therapy system comprising:

ultrasonic observation and therapy means provided with a bendable curvature part, an observation ultrasonic transducer for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image and a therapeutic ultrasonic transducer for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part so as to be focused;

signal processing means for conducting signal processing for generating a signal driving said observation ultrasonic transducer and for generating an image with respect to the ultrasonic wave which is received by said observation ultrasonic transducer;

drive means for driving said therapeutic ultrasonic transducer to generate a drive signal for generating the therapeutic ultrasonic wave; and

display means for displaying an image signal which is generated by said signal processing means.

50. A system according to claim 49, further comprising focusing-point adjusting means for variably setting a focusing point at which the ultrasonic wave which is outputted from said therapeutic ultrasonic transducer is focused within the object part.

51. A system according to claim 50, wherein said focusing-point adjusting means is depth adjusting means for variably setting the focusing point with respect to a depth direction of said object part.

52. A system according to claim 50, wherein said focusing-point adjusting means variably sets the focusing point with respect to a direction perpendicular to the depth direction of said object part.

53. A system according to claim 50, wherein said focusing-point adjusting means is movement means for moving said therapeutic ultrasonic transducer.

54. An ultrasonic diagnosis and therapy system comprising:

ultrasonic observation and therapy means provided, on the side of a distal end of an elongated insertion part capable of being inserted into a coelom, with an illumination optical system for outputting illumination light, an observation optical system for optically observing an object which is illuminated by said illumination light, an observation ultrasonic transducer for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image and a therapeutic ultrasonic transducer for irradiating the ultrasonic wave for conducting therapy with respect to an object part so as to be focused;

signal processing means for conducting signal processing for generating a signal driving said observation ultrasonic transducer and for generating an image with respect to an ultrasonic wave which is received by said observation ultrasonic transducer;

drive means for driving said therapeutic ultrasonic transducer to generate a drive signal for generating a therapeutic ultrasonic wave; and

display means for displaying the image signal which is generated by said signal processing means.

55. An ultrasonic diagnosis and therapy system according to claim 54, wherein acoustic variation of the object part which is in the course of the fact that said therapeutic ultrasonic wave is irradiated in focusing is capable of being displayed.

56. An ultrasonic diagnosis and therapy system according to claim 54, wherein said display means includes a head mount display which is capable of being mounted on a head of an operator and which has respective display faces in front of eyes of said operator.

57. An ultrasonic diagnosis and therapy system according to claim 54, further comprising an X-ray CT device for displaying a tomographic image due to an X-ray.

58. An ultrasonic diagnosis and therapy system according to claim 54, further comprising an MRI device for displaying a tomographic image which utilizes nuclear magnetic resonance.

59. An ultrasonic diagnosis and therapy system comprising:

ultrasonic observation and therapy means provided, on the side of a distal end of an elongated insertion part insertable into a coelom, with an observation ultrasonic transducer for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image and a therapeutic ultrasonic transducer for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part so as to be focused;

signal processing means for conducting signal processing for generating a signal driving said observation ultrasonic transducer and for generating an image signal with respect to an ultrasonic signal which is received by said observation ultrasonic transducer;

drive means for driving said therapeutic ultrasonic transducer to generate a drive signal for generating the therapeutic ultrasonic wave;

display means for displaying said ultrasonic image corresponding to said image signal; and

irradiation-state confirmation means for displaying a state of the object part in the vicinity of a focusing point to which said therapeutic ultrasonic wave is irradiated, onto said display means as said ultrasonic image.

60. An ultrasonic probe comprising:

an elongated insertion part insertable into a coelom;

a therapeutic ultrasonic transducer arranged on the side of a distal end of said insertion part, for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part so as to be focused; and

an observation ultrasonic transducer arranged on the side of the distal end of said insertion part, for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image, over a set scanning range including a direction in which said therapeutic ultrasonic wave is outputted.

61. An ultrasonic probe comprising:

an elongated insertion part insertable into a coelom;

a therapeutic ultrasonic transducer arranged on the side of a distal end of said insertion part, for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part so as to be focused; and

an observation ultrasonic transducer arranged on the side of the distal end of said insertion part, for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image so as to be overlapped with a direction in which said therapeutic ultrasonic wave is emanated.

62. An ultrasonic endoscope comprising:

an elongated insertion part insertable into a coelom;

an observation ultrasonic transducer arranged on the side of a distal end of said insertion part, for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image;

a therapeutic ultrasonic transducer arranged on the side of the distal end of said insertion part, for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part, so as to be focused; and

optical observation means arranged on the side of the distal end of said insertion part, including an illumination window for outputting illumination light and an observation window for optically observing an object which is illuminated by said illumination light, said optical observation means including an optical observation range which is set so as to be overlapped with a direction in which said therapeutic ultrasonic wave is outputted.

63. An ultrasonic diagnosis and therapy system comprising:

ultrasonic observation and therapy means provided, on the side of a distal end of an elongated insertion part insertable into a coelom, with an observation ultrasonic transducer for transmitting and receiving an observation ultrasonic wave to acquire an ultrasonic image and a therapeutic ultrasonic transducer for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part so as to be focused;

signal processing means for conducting signal processing for generating a signal driving said observation ultrasonic transducer and for generating an image signal from an ultrasonic signal which is received by said observation ultrasonic transducer;

drive means for driving said therapeutic ultrasonic transducer to generate a drive signal for generating the therapeutic ultrasonic wave;

display means to which said image signal is inputted for displaying said ultrasonic image corresponding to said image signal;

scanning means for scanning said observation ultrasonic wave; and

lock means for locking a focusing point of said therapeutic ultrasonic wave to a predetermined position on said ultrasonic image, with respect to scanning of said observation ultrasonic wave.

64. An ultrasonic probe comprising:

an elongated insertion part insertable into a coelom;

a therapeutic ultrasonic transducer arranged on the side of a distal end of said insertion part, for outputting a therapeutic ultrasonic wave for conducting therapy With respect to an object part so as to be focused;

an observation ultrasonic transducer arranged on the side of the distal end of said insertion part, for transmitting and receiving an observation ultrasonic wave over a scanning range which is set to acquire an ultrasonic image; and

a lock mechanism for locking a focusing point of said therapeutic ultrasonic wave in a predetermined direction of said scanning range.

65. An ultrasonic probe comprising:

an elongated insertion part capable of being inserted into a coelom;

a therapeutic ultrasonic transducer arranged on the side of a distal end of said insertion part, for outputting a therapeutic ultrasonic wave for conducting therapy with respect to an object part so as to be focused; and

an observation ultrasonic transducer arranged on a plane substantially the same as said therapeutic ultrasonic transducer, on the side of the distal end of said insertion part, for transmitting and receiving an observation ultrasonic wave.

66. A therapy method comprising the steps of:

a first step of inserting, into a coelom, an ultrasonic probe which is provided, on the side of a distal end of an insertion part, with an observation ultrasonic transducer for transmitting and receiving an observation ultrasonic wave for acquiring an ultrasonic image and a therapeutic ultrasonic transducer for outputting a therapeutic ultrasonic wave;

a second step of bringing the side of the distal end of said ultrasonic probe into intimate contact with the vicinity of a diagnosis object part within the coelom, to set the ultrasonic wave to a state in which the ultrasonic wave is capable of being outputted toward the diagnosis object part;

a third step of displaying an ultrasonic image from the ultrasonic signal which is received by said observation ultrasonic transducer, by scanning of said observation ultrasonic wave;

a fourth step of modifying a scanning direction of the observation ultrasonic wave which is outputted toward said diagnosis object part, to set a lesion part to be conducted in therapy, to a state in which said lesion part is displayed on said ultrasonic image;

a fifth step of adjusting the side of said ultrasonic probe so that a position on said ultrasonic image which corresponds to a focusing point of said therapeutic ultrasonic wave and a display position of said lesion part are in agreement with each other;

a sixth step of conducting high-temperature therapy due to irradiation of said therapeutic ultrasonic wave with respect to said lesion part set to said focusing point;

a seventh step of observing a state of said lesion part to which said therapeutic ultrasonic wave is irradiated, on said ultrasonic image; and

an eighth step of further conducting the irradiation of said therapeutic ultrasonic wave in case where said lesion part observed on said ultrasonic image does not reach a state suitable for therapy.