Pharmaceutical product container with two separate substances and a mixing device and dosed dispensation

• US 5,474,209 A
• Filed: 07/02/1993
• Issued: 12/12/1995
• Est. Priority Date: 07/02/1992
• Status: Expired due to Term

• Current Assignee: Laboratories CUSI SA
• Original Assignee: Laboratories CUSI SA
• Inventors: Gimenez Guasch, Francesc X., Vallet Mas, Jose A.
• Primary Examiner(s): Oberleitner, Robert J.
• Assistant Examiner(s): Bomberg, Kenneth
• Application Number:
  US08/087,612
• Time in Patent Office: 893 Days
• Field of Search: 222/80, 222/81, 222/83, 222/145, 222/153, 206/219, 206/221, 215/DIG. 8, 604/410, 604/414, 604/82, 604/87, 604/88, 604/89
• US Class Current: 222/83
• CPC Class Codes: B65D 51/285 ruptured by a sharp element, e.g. a cutter or a piercer
• CPC Class Codes: Y10S 215/08 Mixing

Abstract

A pharmaceutical product container houses two separate substances. The container includes a bottom container having a first substance. The bottom container has an edge disposed at an open mouth thereof. A top container has a second substance. The top container has a frangible bottom wall. The top container has a flap extending radially outwardly. The flap includes an annular rib. The annular rib has a device for retaining the edge of the bottom container. The top container has a neck portion extending axially remote from the bottom wall. The neck has a helical thread to receive the cap. The neck includes a plurality of radially extending toothed projections about its perimeter. A tubular sleeve is disposed within the top container. The tubular sleeve is axially moveable with respect to the top container. The tubular sleeve has a first end and a second end. The first end has a device for partially cutting the bottom wall of the top container upon rotation of the cap onto the neck to create axial movement of the tubular sleeve in a first direction. The second end terminates with a radially protruding wing and a truncated-cone shaped portion. The truncated-cone shaped portion has a device for functioning as a medicinal dropper. A seal is connected to the cap with a perforated connection. The seal includes a plurality of radially extending toothed projections about its perimeter which mate with the plurality of projections in the neck such that upon rotation of the cap off of the neck, the perforated connection breaks and the seal can be removed. The cap can then be rotated onto the neck to effect the cutting of the bottom wall.

Claims

1. A pharmaceutical product container for housing two separate substances comprising:

a bottom container having means for receiving a first substance, said bottom container having an edge disposed at an open mouth of said bottom container;

a cap;

a top container having means for receiving a second substance, said top container having a frangible bottom wall, said top container having a flap extending radially outwardly, said flap includes an annular rib, said annular rib having means for retaining said edge of said bottom container, said top container having a neck portion extending axially remote from said bottom wall, said neck having a helical thread to receive said cap, said neck including a plurality of radially extending toothed projections about its perimeter;

a tubular sleeve being disposed within said top container, said tubular sleeve being axially moveable with respect to said top container, said tubular sleeve having a first end and a second end, said first end having means for partially cutting said bottom wall of said top container upon rotation of said cap onto said neck to create axial movement of said tubular sleeve in a first direction, said second end terminating with a radially protruding wing and a truncated-cone shaped portion, said truncated-cone shaped portion having means for functioning as a medicinal dropper; and

a seal being connected to said cap with a perforated connection, said seal including a plurality of radially extending toothed projections about its perimeter which mate with said plurality of projections in said neck such that upon rotation of said cap off of said neck, said perforated connection breaks and said seal can be removed, said cap can then be rotated onto said neck to effect said cutting of said bottom wall.

2. The container according to claim 1, wherein said partial cutting means includes an edge of said tubular sleeve having a bevelled edge.

3. The container according to claim 1, wherein said partial cutting means includes an edge of said tubular sleeve having a pointed longitudinal projection which has a decreasing cross section in a downward direction.

4. The container according to claim 3, wherein a longitudinal recess is disposed in said tubular sleeve diametrically opposite to said pointed longitudinal projection, said recess preventing said bottom wall from being completely separated from said top container when said bottom wall is cut.

5. The container according to claim 1, wherein one of said bottom wall and said tubular sleeve includes a perforated line to facilitate the cutting thereof.

6. The container according to claim 1, wherein said bottom wall has a thick center region and has a reduced wall thickness about its perimeter to permit adequate cutting of said bottom wall without producing fragmented particles.

7. The container according to claim 1, wherein said flap surrounds a neck portion of said bottom container.

8. The container according to claim 1, wherein said means for functioning as a medicinal dropper includes a cylinder disposed coaxially within said tubular sleeve.

9. The container according to claim 1, wherein said radially protruding wing of said tubular sleeve has an outer peripheral edge having a conical shape to define a bevel, said neck of said top container having an annular recess disposed in a mouth of said top container to receive and retain said bevel thereby retaining said tubular sleeve in said top container.

10. The container according to claim 1, wherein said bottom container has a sealing ring which seals with an outside wall of said top container, said sealing ring being reinforced by said edge of said bottom container when retained by said annular rib, said tubular sleeve has a sealing ring that cooperates with at least one sealing ring disposed on an inner surface of said top container to effect a seal between said tubular sleeve and said top container after said cutting.

11. The container according to claim 10, wherein said tubular sleeve has on its second end a recess which mates with a corresponding projection on said cap to permit sealing between said cap and said tubular sleeve.