Implantable drug delivery pump
First Claim
1. An apparatus for regulating a condition or concentration of a constituent in a person, animal, or living tissue the constituent or condition being increasable by delivery of an agent to the person, animal or living tissue, and decreasable by delivery of a counteragent to the person, animal or living tissue;
- the apparatus comprising;
a sensor implanted in the person or tissue, the sensor producing a detectable signal which varies with the concentration of the constituent or the existence of the condition in a medium surrounding the sensor;
a source of agent;
a source of counteragent;
delivery means for controllably delivering each of the agent and counteragent to the person or tissue; and
a controller for detecting the signal produced by the sensor and for determining if the concentration of the constituent or the condition is within a predetermined range, the controller causing the delivery means to selectively deliver agent or counteragent to maintain the concentration of the constituent or the condition within the predetermined range.
2 Assignments
0 Petitions
Accused Products
Abstract
A method and apparatus for maintaining the concentration of glucose in a person, animal or tissue within a predetermined range is disclosed. An implanted sensor of living cells produces a detectable electrical signal which varies with the concentration of glucose. A controller detects the electrical signal produced by the sensor and determines if the concentration of glucose is within the predetermined range. If the glucose is too low or too high, the controller activates a pump causing either glucose or glucagon, or insulin to be delivered to the person until the glucose level is within the predetermined range. A separate pump for delivering each of the glucose and insulin may be used, or a single pump which is switchable between them may be used. The system may be adapted to maintain other constituents or conditions within a predetermined range by changing the sensor in use, and by using agents and counteragents appropriate to the condition or constituent level being monitored.
568 Citations
17 Claims
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1. An apparatus for regulating a condition or concentration of a constituent in a person, animal, or living tissue the constituent or condition being increasable by delivery of an agent to the person, animal or living tissue, and decreasable by delivery of a counteragent to the person, animal or living tissue;
the apparatus comprising; a sensor implanted in the person or tissue, the sensor producing a detectable signal which varies with the concentration of the constituent or the existence of the condition in a medium surrounding the sensor; a source of agent; a source of counteragent; delivery means for controllably delivering each of the agent and counteragent to the person or tissue; and a controller for detecting the signal produced by the sensor and for determining if the concentration of the constituent or the condition is within a predetermined range, the controller causing the delivery means to selectively deliver agent or counteragent to maintain the concentration of the constituent or the condition within the predetermined range. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method for maintaining a condition or concentration of a constituent in a person, animal or other living tissue within a predetermined range, the constituent or condition being increasable by delivery of an agent to the person, animal or living tissue and decreasable by delivery of a counteragent to the person, animal or living tissue;
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the method comprising; implanting a sensor in the person or tissue, the sensor producing a detectable signal which varies with the concentration of the constituent or the existence of the condition in a medium surrounding the sensor; providing a source of agent; providing a source of counteragent; detecting the signal produced by the sensor and determining if the concentration of the constituent or the condition is within the predetermined range; and selectively and controllably delivering the agent or counteragent to the person, animal or tissue to maintain the concentration of the constituent or the condition within the predetermined range. - View Dependent Claims (11, 12, 13, 14)
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15. An apparatus for regulating glucose levels in a person, the apparatus comprising:
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a sensor implanted in the person, the sensor comprising a mass of living cells which generate a detectable electrical signal which varies with the concentration of glucose in the person; a source of glucose or glucagon; a source of insulin; at least one pump for controllably delivering the glucose or glucagon and insulin to the person; and a controller for detecting the electrical signal produced by the sensor and for determining if the glucose concentration in the person is within a predetermined range, the controller causing the pump to selectively deliver glucose or glucagon, or insulin to the person until the concentration of glucose in the person is within the predetermined range. - View Dependent Claims (16, 17)
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Specification