Low pressure neural contact structure

• US 5,476,494 A
• Filed: 04/28/1994
• Issued: 12/19/1995
• Est. Priority Date: 09/11/1992
• Status: Expired due to Term

• Current Assignee: Massachusetts Eye And Ear Infirmary (Foundation of The Massachusetts Eye and EAR Infirmary Incorporated)
• Original Assignee: Massachusetts Institute of Technology
• Inventors: Edell, David J., Wyatt, John L. Jr., Rizzo, Joseph III
• Primary Examiner(s): Prebilic, Paul B.
• Application Number:
  US08/234,725
• Time in Patent Office: 600 Days
• Field of Search: 623/24, 623/25, 128/642, 607/116, 607/118
• US Class Current: 607/116
• CPC Class Codes: A61N 1/0543 Retinal electrodes

Abstract

A low-pressure neural contact structure for contact with neural tissue, for example, neural tissue of the retina within which are ganglion cells to be electrically stimulated. The contact structure comprises a first portion for attachment to a first bodily location, such as the inner surface of the retina, and a second portion interconnected with the first portion via an interconnection and being held in contact with the neural tissue. The interconnection exhibits a weak restoring force which in conjunction with the geometry of said second portion provides a preselected desired pressure of contact against the neural tissue. As adapted for the retina, the interconnection exhibits a weak restoring force developed in response to curvature of the interconnection along the inner radius of the retina.

Claims

1. A low-pressure neural contact structure for contact with neural tissue of the retina within which are ganglion cells to be electrically stimulated comprising:

a first portion for attachment to a first location on an inner surface of the retina, and

a second portion interconnected with said first portion via an interconnection adapted to contact a second location on the inner surface of the retina adjacent to said ganglion cells to be stimulated, said interconnection easily conforming to contours in said neural tissue to exhibit a weak restoring force in response to curvature of the interconnection along an inner radius of the retina to provide a desired pressure of contact of said second portion against said neural tissue of below 10 mm mercury, the desired pressure sufficient to permit stimulation of the neural tissue without damage to said neural tissue.

2. The neural contact of claim 1 wherein said first and second portions together comprise an integral structure.

3. The neural contact of claim 2 wherein said integral structure is of a generally rectangular geometry.

4. The neural contact of claim 3 wherein said integral structure comprises a cantilever.

5. The neural contact of either of claims 1 or 4 wherein said second portion provides mechanical support for a stimulating electrode structure positioned on said second portion for stimulating said ganglion cells.

6. The neural contact of claim 4 wherein said cantilever comprises silicon.

7. The neural contact of claim 6 wherein said second portion of said cantilever comprises an array of stimulating electrodes for stimulating said ganglion cells.

8. The neural contact of claim 7 further comprising an encapsulation layer of biocompatible material which encapsulates said cantilever.

9. The neural contact of claim 8 wherein said encapsulation layer comprises silicone.

10. The neural contact of claim 8 wherein said encapsulation layer overhangs edges of said cantilever.

11. The neural contact of claim 9 wherein said encapsulation layer material in the location of said first portion is thicker than said encapsulation layer material in the location of said second portion.

12. The neural contact of claim 10 wherein said encapsulation layer material in the location of said edges of said cantilever comprises perforations.

13. The neural contact of claim 9 wherein said encapsulation layer comprises an array of channels located at a position over said second portion corresponding to said array of stimulating electrodes.

14. The neural contact of claim 9 wherein said cantilever is between 2-40 microns-thick.

15. The neural contact of claim 14 wherein said cantilever is between 5-15 microns-thick.

16. The neural contact of claim 14 wherein said cantilever is between 2 mm-5 cm-long.

17. The neural contact of claim 16 wherein said cantilever is between 0.5-2 cm-long.

18. The neural contact of claim 16 wherein said cantilever is between 0.5 mm-1 cm-wide.

19. The neural contact of claim 18 wherein said cantilever is between 1-3 mm-wide.

20. The neural contact of claim 14 wherein said encapsulation layer is between 5-25 microns-thick.

21. The neural contact of claim 9 further comprising a silicone rib positioned on said cantilever to bend said cantilever in a predetermined geometric shape.

22. The neural contact of claim 7 wherein the width of said cantilever in the location of said first portion and in the location of said second portion is greater than the width of said cantilever in the location of said interconnection.