Apparatus and method for stabilizing the ventricular rate of a heart during atrial fibrillation

• US 5,480,413 A
• Filed: 11/30/1994
• Issued: 01/02/1996
• Est. Priority Date: 11/30/1994
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Original Assignee: Telectronics Pacing Systems, Inc (Abbott Laboratories)
• Inventors: Greenhut, Saul, Nappholz, Tibor, Dawson, Albert, Steinhaus, Bruce
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): HUANG, STEPHEN D
• Application Number:
  US08/347,279
• Time in Patent Office: 398 Days
• Field of Search: 607/9, 607/10, 607/11, 607/12, 607/13, 607/14, 607/15, 607/16, 607/17, 607/18, 607/27, 607/28, 607/30-32
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/36521 the parameter being derived from measurement of an electrical impedance

Abstract

A pacemaker is provided in which ventricular rate instability is detected and automatically corrected by gradually increasing the ventricular pacing rate. Once the ventricle is stabilized, its pacing rate is gradually decreased as much as possible without losing ventricular stability. Ventricular instability can be a result of an atrial tachyrhythmia such as atrial fibrillation. Therefore, if the pacemaker is a dual chamber pacemaker, its operation is switched to a single chamber pacing mode thereby decoupling the ventricular pacing signals from the atrial pacing signals and atrial triggered ventricular pacing is inhibited until the atrial fibrillation terminates.

Claims

1. An implantable pacemaker for insertion into a patient for stimulating the patient'"'"'s heart, said pacemaker comprising:

means for detecting R--R intervals between consecutive R-waves in said heart, said R--R intervals defining a ventricular rate in a ventricle of said heart;

means for detecting an atrial tachyrhythmia in an atrium of said heart;

means for determining if said ventricular rate is unstable in response to said atrial tacharrhythmia based on said R--R intervals;

means for pacing said ventricle at a ventricular pacing rate; and

means for stabilizing said ventricular rate by increasing said ventricular pacing rate when said ventricular rate is unstable.

2. The pacemaker of claim 1 wherein said means for determining includes means for monitoring a ventricular rate variability, said ventricular rate variability being determined by comparing a predetermined number of R--R intervals to an average R--R interval.

3. The pacemaker of claim 1 further comprising means for decreasing said ventricular pacing rate gradually while maintaining cardiac stability.

4. The pacemaker of claim 1 further comprising means for detecting an atrial fibrillation of said heart.

5. The pacemaker of claim 4 further comprising means for pacing the atrium at an atrial pacing rate, said atrial pacing means being disabled when said atrial fibrillation is detected.

6. The pacemaker of claim 1 wherein said means for detecting said R--R intervals includes means for detecting a plurality of intervals RR_i between R waves, means for determining normalized value for said RR_i and means for determining when said normalized value exceeds a preselected threshold.

7. The pacemaker of claim 1 further comprising means for generating a metabolic indicated rate, said means for determining if said ventricular rate is stable including means for comparing said metabolic indicated rate with said ventricular rate.

8. A pacemaker implantable in a patient for stimulating the heart, said pacemaker comprising:

means for generating atrial induced pacing signals for pacing an atrium;

means for generating ventricular induced pacing signals for pacing a ventricle, in a normal mode of operation, said ventricular induced signals being coupled to said atrial induced pacing signals;

means for detecting R--R intervals between consecutive R-waves in said heart;

means for detecting a ventricular rate instability of a ventricular rate by analyzing said R--R intervals;

means for detecting atrial tachyrhythmia; and

means for increasing said ventricular induced pacing signals gradually when said ventricular rate instability is detected until the ventricular rate is stabilized.

9. The pacemaker of claim 8 further comprising means for detecting atrial fibrillation.

10. The pacemaker of claim 9 further comprising decoupling means for decoupling said ventricular induced pacing signals from said atrial induced pacing signals when the atrial fibrillation is detected.

11. The pacemaker of claim 8 wherein said means for detecting R--R intervals includes means for measuring an interval between adjacent ventricular signals and comparing means for comparing said intervals to a threshold level.

13. The method of claim 10 further comprising the step of decreasing said rate while maintaining ventricular stability.

12. A method of providing pacing signals to a heart with an implanted pacemaker, said method comprising the steps of:

applying ventricular pacing signals to a ventricle;

monitoring an atrium to determine atrial instability wherein said atrium exhibits random atrial beats by measuring R--R intervals between consecutive R waves in said ventricle; and

increasing a rate of said ventricular pacing signals gradually until ventricular rate stability is achieved.