Flow cell for calorimetric measurements
First Claim
1. A flow cell for calorimetric measurements comprising a body with at least two flow channels sharing one common outlet opening, and each one of said at least two flow channels having a separate inlet opening and extending to said outlet opening, said flow cell further comprising a thermoelectric detector for monitoring temperature changes, which occur during chemical or biochemical processes in a measuring volume being located below said at least two flow channels in close vicinity to said outlet opening of said at least two flow channels wherein said outlet opening extends vertically through said body and ends in a recess, which is provided in said body of said flow cell below said at least two flow channels, said recess being adapted to accommodate said thermoelectric detector and a spacer element, which is arranged between said body and said thermoelectric detector, said spacer element being provided with central bores, which communicate with said outlet opening, with said measuring volume and with an exit channel, which is provided in said body, and said spacer element having a height such, that a gap between said spacer element and an active surface of said thermoelectric detector defines said measuring volume, and whereby said body of said flow cell has a good thermal conductivity such, that fluids flowing through said at least two flow channels are thermostatizised prior to entering said measuring volume solely by flowing through said at least two flow channels and free of any external thermostatization means.
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Accused Products
Abstract
A flow cell for calorimetric measurements comprises a body (2) with at least one flow channel (3), which extends between an inlet opening (4) and an outlet opening (5), and a thermoelectric detector (16) for monitoring temperature changes, which occur during chemical or biochemical processes in a measuring volume (17). The measuring volume (17) is arranged in close vicinity of the outlet opening (5). The body (2) of the flow cell (1) has a good thermal conductivity of a magnitude such, that a fluid flowing through the flow channel (3) is thermostatizised prior to entering the measuring volume (17) solely by flowing through the flow channel (3) and free of any external thermostatization means. Thus, a flow cell is provided, which is capable of self-thermostatizing a fluid flowing therethrough.
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Citations
19 Claims
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1. A flow cell for calorimetric measurements comprising a body with at least two flow channels sharing one common outlet opening, and each one of said at least two flow channels having a separate inlet opening and extending to said outlet opening, said flow cell further comprising a thermoelectric detector for monitoring temperature changes, which occur during chemical or biochemical processes in a measuring volume being located below said at least two flow channels in close vicinity to said outlet opening of said at least two flow channels wherein said outlet opening extends vertically through said body and ends in a recess, which is provided in said body of said flow cell below said at least two flow channels, said recess being adapted to accommodate said thermoelectric detector and a spacer element, which is arranged between said body and said thermoelectric detector, said spacer element being provided with central bores, which communicate with said outlet opening, with said measuring volume and with an exit channel, which is provided in said body, and said spacer element having a height such, that a gap between said spacer element and an active surface of said thermoelectric detector defines said measuring volume, and whereby said body of said flow cell has a good thermal conductivity such, that fluids flowing through said at least two flow channels are thermostatizised prior to entering said measuring volume solely by flowing through said at least two flow channels and free of any external thermostatization means.
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2. A flow cell for calorimetric measurements comprising a body with at least one flow channel, which extends between an inlet opening and an outlet opening, and which is spiral shaped such, that a respective outer winding, thermally shields a respective neighboring inner winding said flow cell further comprising a thermoelectric detector for monitoring temperature changes, which occur during chemical or biochemical processes in a measuring volume being located below said at least one flow channel in close vicinity to said outlet opening of said at least one flow channel, wherein said outlet opening extends vertically through said body and ends in a recess, which is provided in said body of said flow cell below said at least one channel, said recess being adapted to accommodate said thermoelectric detector and a spacer element, which is arranged between said body and said thermoelectric detector, said spacer element being provided with central bores, which communicate with said outlet opening, with said measuring volume and with an exit channel, which is provided in said body, and said spacer element having a height such, that a gap between said spacer element and an active surface of said thermoelectric detector defines said measuring volume, and whereby said body of said flow cell has a good thermal conductivity such, that a fluid flowing through said flow channel is thermostatizised prior to entering said measuring volume solely by flowing through said flow channel and free of any external thermostatization means.
- 3. A flow cell for calorimetric measurements comprising a body with at least one flow channel, which flow channel extends between an inlet opening and an outlet opening, and a thermoelectric detector for monitoring temperature changes, which occur during chemical or biochemical processes in a measuring volume being located below said at least one flow channel in close vicinity to said outlet opening of said at least one flow channel, wherein said outlet opening extends vertically through said body and ends in a recess, which is provided in said body of said flow cell below said at least one channel, said recess being adapted to accommodate said thermoelectric detector and a spacer element, which is arranged between said body and said thermoelectric detector, said spacer element being provided with central bores, which communicate with said outlet opening, with said measuring volume and with an exit channel, which is provided in said body, and said spacer element having a height such, that a gap between said spacer element and an active surface of said thermoelectric detector defines said measuring volume, and whereby said body of said flow cell has a good thermal conductivity such, that a fluid flowing through said flow channel is thermostatizised prior to entering said measuring volume solely by flowing through said flow channel and free of any external thermostatization means.
Specification