Pregna-1,4-diene3,20-dione-16-17-acetal-21 esters, process for their preparation, composition, and methods for the treatment of inflammatory conditions
First Claim
1. A compound of the formula ##STR20## in the form of an R epimer, an S epimer, or a stereoisomeric mixture of the R and S epimers in terms of the orientation of the substituents on the carbon atom at position 22, wherein:
- R1 is cyclohexyl,R2 is a member selected from the group consisting of ##STR21## and wherein X1 and X2 may be the same or different and each is a member selected from the group consisting of hydrogen and fluorine.
9 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates to compounds of the formula: ##STR1## in which X1 and X2 correspond to H or F without distinction; R1 represents the following radicals: ##STR2## and R2 represents the radicals ##STR3## in the form of an R epimer, an S epimer, or a stereoisomeric mixture of the R and S epimers in terms of the orientation of the substituents on the carbon atom at position 22, novel intermediates and a method of their preparation by hydrolysis-ketalization, and use of such compounds as drugs and/or therapeutic agents.
-
Citations
12 Claims
-
1. A compound of the formula ##STR20## in the form of an R epimer, an S epimer, or a stereoisomeric mixture of the R and S epimers in terms of the orientation of the substituents on the carbon atom at position 22, wherein:
-
R1 is cyclohexyl, R2 is a member selected from the group consisting of ##STR21## and wherein X1 and X2 may be the same or different and each is a member selected from the group consisting of hydrogen and fluorine. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
-
Specification