Method and apparatus for analyzing the electrical activity of the heart

• US 5,483,968 A
• Filed: 05/21/1992
• Issued: 01/16/1996
• Est. Priority Date: 06/25/1991
• Status: Expired due to Fees

• Current Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD.
• Original Assignee: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD.
• Inventors: Vitsnudel, Ilia, Gilat, Shlomo, Adam, Dan, Sideman, Samuel
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US07/886,227
• Time in Patent Office: 1,335 Days
• Field of Search: 128/696, 128/699, 128/702, 128/710
• US Class Current: 600/508
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/6805 Vests
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period

Abstract

A method and apparatus for analyzing the electrical activity of the heart by Body Surface Potential Mapping (BSMP) in which an array of electrodes are applied over the thoracic region of a subject'"'"'s body for producing measurements of the electrical signals generated in the thoracic region, and the measurements are processed for indicating certain electrical events in the subject'"'"'s body. The array of electrodes are utilized to measure only the times of crossing of the electrical signals over a preset threshold.

Claims

1. A method of analyzing the electrical activity of the heart by Body Surface Potential Mapping (BSMP), comprising, applying an array of electrodes over the thoracic region of a subject'"'"'s body for producing measurements of the electrical signals generated in said thoracic region, and processing said measurements for indicating certain electrical events in the subject'"'"'s body;

characterized in utilizing said array of electrodes to measure only the times of crossing of the electrical signals over a preset threshold.

2. The method according to claim 1, wherein the processing of said measurements includes the following steps:

(a) estimating the covariance matrix of random processes from the measurements by said array of electrodes;

(b) decomposing said covariance matrix into the eigenfunction basis;

(c) evaluating, from a partial set of said measurements for the respective subject, the coefficent of a linear combination of computed eigenfunctions; and

(d) expanding said computed eigenfunctions to obtain a complete reconstruction of the BSPM.

3. The method according to claim 2, wherein the reconstruction of the BSPM in step (d) is performed by dividing the array of electrodes into a plurality of intermittent grids, and utilizing a corresponding number of the threshold levels, one for each of said grids.

4. The method according to claim 3, wherein said reconstruction is performed by dividing the array of electrodes into four intermittent grids and utilising four threshold levels, one for each of said grids.

5. A method analyzing the electrical activity of the heart by Body Surface Potential Mapping (BSMP), comprising, applying an array of electrodes over the thoracic region of a subject'"'"'s body for producing measurements of the electrical signals generated in said thoracic region, and processing said measurements for indicating certain electrical events in the subject'"'"'s body;

characterized in that the processing of said measurements incudes the following steps;

(a) estimating the covariance matrix of random processes from the measurements by said array of electrodes;

(b) decomposing said covariance matrix into the eigenfunction basis;

(c) evaluating from a partial set of said measurements for the respective subject, the coefficient of a linear combination of computed eigenfunctions; and

(d) expanding said computed eigenfunctions to obtain a complete reconstruction of the BSPM.

6. The method according to claim 5, further characterized in that said array of electrodes are utilized to measure only the times of crossing of the electrical signals over a preset threshold.

7. The method according to claim 6, wherein said reconstruction of the BSPM is performed by dividing the array of electrodes into a plurality of intermittent grids, and utilizing a corresponding number of the threshold levels, one for each said grids.

8. The method according to claim 7, wherein said reconstruction is performed by dividing the array of electrodes into four intermittent grids and using four threshold levels, one for each of said grids.

9. The method according to claim 5, wherein said measurements of the thoracic region of the subject'"'"'s body, and said reconstruction of the BSPM, are thresholded twice at two chosen levels, and annuli are calculated for storage, display, and further processing.

10. Apparatus for analyzing the electrical activity of the heart by Body Surface Potential Mapping (BSPM), comprising:

an array of electrodes placeable over the thoracic region of a subject'"'"'s body;

measuring means for producing measurements of the electrical signals generated in said thoracic region as detected by said array of electrodes;

and processor means for procesing said measurements for indicating certain electrical events in the subject'"'"'s body;

characterized in that said measurement means measures only the times of crossing of the electrical signals over a preset threshold as detected by said array of electrodes.

11. The apparatus according to claim 10, wherein said processor means includes:

(a) means for estimating the covariance matrix of random processes from the measurements by said array of electrodes;

(b) means for decomposing said covariance matrix into the eigenfunction basis;

(c) means for evaluating, from a partial set of said measurements for the respective subject, the coefficent of a linear combination of computed eigenfunctions; and

(d) means for expanding said computed eigenfunctions to obtain a complete reconstruction of the BSPM.

12. The apparatus according to claim 11, wherein said means (d) performs said reconstruction by dividing the array of electrodes into a plurality of intermittent grids and utilizing a corresponding number of threshold levels, one for each of said grids.

13. The apparatus according to claim 12, wherein said reconstruction is effected by four intermittent grids and by utilizing four threshold levels, one for each of said grids.

14. Apparatus for analyzing the electrical activity of the heart by Body Surface Potential Mapping (BSPM), comprising:

an array of electrodes placeable over the thoracic region of a subject'"'"'s body;

measuring means for producing measurements of the electrical signals generated in said thoracic region as detected by said array of electrodes;

and processor means for processing said measurements for indicating certain electrical events in the subject'"'"'s body;

characterized in that said processor means includes;

(a) means for estimating the covariance matrix of random processes from the measurements by said array of electrodes;

(b) means for decomposing said covariance matrix into the eigenfunction basis;

(c) means for evaluating, from a partial set of said measurements for the respective subject, the coefficent of a linear combination of computed eigenfunctions; and

(d) means for expanding said computed eigenfunctions to obtain a complete reconstruction of the BSPM.

15. The apparatus according to claim 14, further characterized in that said electrical measuring circuit for each electrode measures only the times of crossing of the electrical signals over a preset threshold.

16. The apparatus according to claim 15, wherein said means (d) performs said reconstruction by dividing the array of electrodes into a plurality of intermittent grids and utilizing a corresponding number of threshold levels, one for each of said grids.

17. The apparatus according to claim 16, wherein said reconstruction is effected by four intermittent grids and by utilizing four threshold levels, one for each of said grids.