Diffusion weighted magnetic resonance imaging
First Claim
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1. A method for motion compensated, diffusion-weighted magnetic resonance imaging comprising:
- applying a first radio frequency pulse to an imaging volume;
applying at least one first magnetic field gradient to the imaging volume, said at least one first magnetic field gradient being diffusion sensitive;
applying a second radio frequency pulse;
waiting a selected delay period and applying a third radio frequency pulse that is synchronized with a cardiac cycle relative to the first radio frequency pulse;
applying a second magnetic field gradient to the imaging volume; and
acquiring data during a data acquisition period of less than about 200 milliseconds and forming an image of the imaging volume with the acquired data.
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Abstract
The present invention relates to the use of diffusion weighted magnetic resonance imaging procedures for the diagnosis of conditions in which blood circulation or similar molecular displacements within biological tissues are measured. Pulse sequences are used in accordance with the invention which suppress the contribution of non-moving tissue or bulk motion.
32 Citations
14 Claims
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1. A method for motion compensated, diffusion-weighted magnetic resonance imaging comprising:
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applying a first radio frequency pulse to an imaging volume; applying at least one first magnetic field gradient to the imaging volume, said at least one first magnetic field gradient being diffusion sensitive; applying a second radio frequency pulse; waiting a selected delay period and applying a third radio frequency pulse that is synchronized with a cardiac cycle relative to the first radio frequency pulse; applying a second magnetic field gradient to the imaging volume; and acquiring data during a data acquisition period of less than about 200 milliseconds and forming an image of the imaging volume with the acquired data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for diffusion-weighted magnetic resonance cardiac imaging comprising:
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applying a first radio frequency pulse to an imaging volume including a cardiac region; applying a diffusion sensitive magnetic field gradient to the imaging volume; applying a second radio frequency pulse to the imaging volume; waiting a selected delay period and applying a third radio frequency pulse to the imaging volume that is synchronized with a cardiac cycle relative to the first radio frequency pulse; applying a second magnetic field gradient to the imaging volume; and recording data during a data acquisition period of less than 200 milliseconds and forming an image of the imaging volume with the recorded data. - View Dependent Claims (10, 11, 12, 13, 14)
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Specification