Probe for medical imaging and therapy using ultrasound

• US 5,492,126 A
• Filed: 05/02/1994
• Issued: 02/20/1996
• Est. Priority Date: 05/02/1994
• Status: Expired due to Term

• Current Assignee: THS International, Inc. (Takai Hospital Supply Co., Ltd.)
• Original Assignee: Focal Surgery
• Inventors: Hennige, Carl W., Driscoll, Edward C. Jr.
• Primary Examiner(s): JAWORSKI, FRANCIS J
• Application Number:
  US08/236,344
• Time in Patent Office: 659 Days
• Field of Search: 128/660.03, 128/662.05, 128/662.06, 601/4, 606/14-16
• US Class Current: 600/439
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/4461 Features of the scanning mechanism, e.g. for moving the transducer within the housing of the probe
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A probe for inspecting and treating an internal organ of a patient. The probe includes a tube having a proximal end and a distal end. The tube has a flexible portion near the distal end. A head is coupled to the flexible portion at the distal end of the tube. The head includes a HIFU transducer. The probe also includes a mechanism for positioning the probe responsive to manipulation by a user. The probe may optionally include a direct viewing mechanism for viewing the area adjacent to the head, a ultrasound system for generating ultrasound images of the area adjacent to the head, and a lighting mechanism for illuminating the area adjacent to the head. The probe may be employed as an endoscope for applying HIFU therapy to internal organs of a patient.

Claims

1. A probe for inspecting and treating an internal organ of a patient, the probe comprising:

a tube having a proximal end and a distal end, the tube having a flexible portion near the distal end;

a head coupled to the flexible portion at the distal end of the tube;

an ultrasonic image generation unit disposed within the head, the ultrasonic image generation unit being configured to generate a first set of ultrasonic waves for generating images of tissue in a first zone;

a HIFU generating unit disposed within the head, the HIFU generating unit being configured to generate a second set of ultrasonic waves for treating tissue in a second zone;

a positioning mechanism for causing the flexible portion to bend responsive to manipulation by a user; and

wherein at least one set of said first and second sets of ultrasonic waves are generated at an angle relative to said head to cause said first zone to intersect with said second zone.

2. The probe of claim 1 further comprising optical visualization mechanism for allowing the user to view tissue adjacent to the probe'"'"'s head.

3. The probe of claim 2, further comprising cooling means for water cooling the HIFU generation unit.

4. The probe of claim 1 wherein the HIFU generating unit is configured to transmit and receive waves to generate an ultrasonic image and to transmit ultrasonic waves for therapy.

5. The probe of claim 1 wherein said ultrasonic image generation unit has a variable orientation relative to said head, the probe further comprising a mechanism for changing said variable orientation to affect the angle, relative to said head, at which said first set of ultrasonic waves is generated.

6. A method for treating an internal organ, the method comprising the steps of:

a) providing a probe having a tube having a first end and a second end, a HIFU generation unit and an ultrasonic image generation unit being supported in a head connected to said first end;

b) inserting the head of the probe into an orifice of a patient;

c) inserting the tube of the probe into the orifice of the patient, thereby causing the head of the probe to project deeper into the patient;

d) causing a portion of the tube adjacent to the head to bend;

e) repeating steps (c) and (d) until the head is adjacent to the internal organ; and

f) energizing the HIFU generation unit to generate a first set of ultrasonic waves toward a first zone on the organ;

g) energizing the ultrasonic image generation unit to generate a second set of ultrasonic waves toward said first zone on said organ while said HIFU generation unit is generating said first set of ultrasonic waves;

h) generating an image of said first zone based on said second set of ultrasonic waves.

7. The method of claim 6 further comprising the steps of:

generating fight to illuminate an area adjacent to the head;

providing a direct viewing mechanism to view the area adjacent to the head; and

directing the insertion of the head and tube based on feedback from the direct viewing mechanism.

8. The method of claim 7 further comprising the steps of:

generating ultrasound images of an area adjacent to the head;

directing the insertion of the head and tube based on the ultrasound images; and

directing the application of therapy based on feedback from the ultrasound images.

9. The method of claim 8 wherein the step of generating ultrasound images is performed based on signals from the HIFU generation unit.

10. The method of claim 6 further comprising the step of altering the orientation of said ultrasonic image generation unit from a first orientation in which said second set of ultrasonic waves are not directed toward said first zone to a second orientation in which said second set of ultrasonic waves are directed toward said first zone.