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Apparatus and methodology for determining oxygen in biological systems

  • US 5,494,030 A
  • Filed: 08/12/1993
  • Issued: 02/27/1996
  • Est. Priority Date: 08/12/1993
  • Status: Expired due to Term
First Claim
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1. Apparatus for measuring oxygen tension in a biological system having a paramagnetic located therein, comprising(a) magnetic means for selectively applying a magnetic field of selectable strength to the biological system,(b) electromagnetic means for selectively applying electromagnetic radiation having a selected substantially constant frequency to the paramagnetic material in the biological system,(c) detection means for detecting the electron paramagnetic spectra of the biological system, said spectra having a selected peak-to-peak line width that is indicative of said oxygen tension in the biological system,(d) resonator means coupled to the electromagnetic means,said resonator means including means for tuning said resonator means to the constant frequency of said electromagnetic means to maintain a substantially constant resonant frequency in response to movements in the biological system,(e) console means in communication with said detection means for displaying said spectra, and(f) computer means connected to said console means for controlling said apparatus, and for analyzing said spectra to determine said oxygen tension.

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