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Selective regulation of B lymphocyte precursors by hormones

  • US 5,494,899 A
  • Filed: 04/07/1994
  • Issued: 02/27/1996
  • Est. Priority Date: 04/07/1993
  • Status: Expired due to Term
First Claim
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1. A method for modulating production of committed mammalian B lymphocyte precursor cells in an animal that has normal bone marrow comprising exposing the cells to a hormone selected from the group consisting of hormones elevated during pregnancy, synthetic analogues of the hormones elevated during pregnancy, eliciting agents of the hormones elevated during pregnancy, and agents that interfere with the synthesis or activity of the hormones elevated during pregnancy, in an amount effective to alter selectively production of B lymphocyte precursor cells by proliferation or differentiation as compared with proliferation of mature B lymphocytes.

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