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Simultaneous angioplasty and phoretic drug delivery

  • US 5,498,238 A
  • Filed: 08/27/1993
  • Issued: 03/12/1996
  • Est. Priority Date: 06/15/1990
  • Status: Expired due to Term
First Claim
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1. A method for simultaneously performing percutaneous translumenal coronary angioplasty and delivering a drug to a localized area of a passageway with a catheter having a proximal end, a distal end, and a balloon operably connected to the distal end, wherein the balloon has a single chamber and a plurality of pores having a diameter of about 1 μ

  • or less, the method comprising the steps of;

    a) advancing the catheter through the passageway until the balloon is adjacent to the localized area;

    b) injecting a fluid through an injection lumen in the catheter and into the single chamber of the balloon causing the balloon to inflate to a pressure of about 2 atmospheres or more and apply a pressure against the localized area of the passageway thereby dilating the localized area of the passageway; and

    c) phoretically transporting the drug to the localized area while simultaneously dilating the localized area of the passageway.

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