Disposable optical agglutination assay device and method for use
First Claim
1. An assay device for use in analyzing a sample of unknown substance by mixing assay reagents with the sample, comprising:
- (a) a housing having a plurality of storage reservoirs, each containing an assay reagent;
(b) an entry port for receiving a sample suspected of containing a target analyte, into said housing, said entry port having an inlet and an outlet;
(c) a controlling track for mixing and delivering the assay reagents in said reservoirs to said entry port via said inlet, and including a plurality of first portions each connected to a respective one of said reservoirs;
(d) said controlling track including a plurality of second portions each for receiving assay reagent from a respective said first portion;
(e) each said second portion including at least one discharge end in the form of a nozzle, said second portions being arranged that assay reagent discharging from a said nozzle of one of said second portions mixes with assay reagent discharging from a said nozzle of another of said second portions; and
(f) means connected to said entry port to allow analysis of the mixed assay reagents and sample after passing through said entry port to said outlet.
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Accused Products
Abstract
An assay device for detecting the presence of analytes in an unknown sample including a reaction system wherein storage reservoirs containing reagent are fluidly connected to a track containing the sample. An actuation mechanism forces the reagent from the reservoirs and into the track where it mixes the reagents together and then with the sample at a first flow rate. The mechanism then reduces the force on the reagent to allow a second flow rate less then the first flow rate to force the reagent and sample mixture through the track so that reaction can occur, whereby a determination as to whether the target analyte was present may be made.
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Citations
20 Claims
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1. An assay device for use in analyzing a sample of unknown substance by mixing assay reagents with the sample, comprising:
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(a) a housing having a plurality of storage reservoirs, each containing an assay reagent; (b) an entry port for receiving a sample suspected of containing a target analyte, into said housing, said entry port having an inlet and an outlet; (c) a controlling track for mixing and delivering the assay reagents in said reservoirs to said entry port via said inlet, and including a plurality of first portions each connected to a respective one of said reservoirs; (d) said controlling track including a plurality of second portions each for receiving assay reagent from a respective said first portion; (e) each said second portion including at least one discharge end in the form of a nozzle, said second portions being arranged that assay reagent discharging from a said nozzle of one of said second portions mixes with assay reagent discharging from a said nozzle of another of said second portions; and (f) means connected to said entry port to allow analysis of the mixed assay reagents and sample after passing through said entry port to said outlet. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification