×

Immediate release tablet cores of insoluble drugs having sustained-release coating

  • US 5,500,227 A
  • Filed: 11/23/1993
  • Issued: 03/19/1996
  • Est. Priority Date: 11/23/1993
  • Status: Expired due to Term
First Claim
Patent Images

1. A sustained release tablet for oral administration, comprising an immediate release tablet core including an insoluble therapeutically active agent having an aqueous solubility of less than or equal to about 5 mg/ml, said tablet core containing a sufficient amount of said therapeutically active agent to render a therapeutic effect, anda film coating formed over said core, said film coating comprising a sufficient amount of a hydrophobic material selected from the group consisting of waxes, shellac, zein, fatty alcohols, hydrogenated vegetable oils, water insoluble celluloses, acrylic polymers and mixtures thereof to provide a sustained release of said therapeutically active agent sufficient to provide a duration of effect from about 8 to about 24 hours when said coated tablet is exposed to aqueous solutions.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×