Method for enhancement of late potentials measurements

• US 5,503,159 A
• Filed: 03/17/1995
• Issued: 04/02/1996
• Est. Priority Date: 03/12/1993
• Status: Expired due to Fees

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Hewlett-Packard Company (HP Inc.)
• Inventors: Burton, David L.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US08/405,657
• Time in Patent Office: 382 Days
• Field of Search: 128/702, 128/703
• US Class Current: 600/516
• CPC Class Codes: A61B 5/336 Magnetic recording apparatus
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives
• CPC Class Codes: A61B 5/7257 using Fourier transforms

Abstract

An ECG recorder and playback unit which includes software-implemented digital signal processing filters which include a method for generating a heart rate variability (HRV) and late potential measurements. The HRV method includes playing back the ECG data on the playback unit and a defining a reference point, usually corresponding to the R-wave peak, on each output ECG signal. An initial period is determined between the reference points. The period is then adjusted so as to align the reference points of the output ECG signals. The amount by which the ECG signals are adjusted is determined by computing a phase difference at a predetermined reference frequency and dividing the phase difference by the reference frequency to produce a period difference. The period is then adjusted by the period difference by adding the period difference to the measured period. The adjusted period is then used to compute the HRV measurement using statistical techniques. In an alternative embodiment of the HRV measurement, an interpolation technique is used to increase the accuracy of the reference point definition and thereby increase the accuracy of the period determination. A phase-ramp technique is employed to improve the frequency resolution of the ECG signal to improve the detection of late potentials.

Claims

1. A method of detecting late potentials comprising the steps of:

extracting a first ECG pulse from an ECG sequence;

extracting a second ECG pulse from said ECG sequence;

computing a phase difference between said first ECG pulse and said second ECG pulse;

deriving a phase ramp that represents the phase difference between said first ECG pulse and said second ECG pulse;

applying the phase ramp to the second ECG pulse to align said first ECG pulse and said second ECG pulse, thereby obtaining aligned ECG signals;

combining the aligned ECG signals to obtain combined ECG signals;

determining the late potentials from the combined ECG signals; and

displaying the late potentials.

2. The method of claim 1 in which the step of computing a phase difference between said first ECG pulse and said second ECG pulse comprises the steps of:

performing a first FFT on the first ECG pulse to produce a first frequency response, said first frequency response including a first phase response for the first ECG pulse;

performing a second FFT on the second ECG pulse to produce a second frequency response, said second frequency response including a second phase response for the second ECG pulse;

detecting the phase of the first ECG pulse at a reference frequency on the first phase response to obtain a first detected phase;

detecting the phase of the second ECG pulse at the reference frequency on the second phase response to obtain a second detected phase; and

subtracting the second detected phase from the first detected phase to produce the phase difference.

3. The method of claim 2 wherein:

the step of combining the aligned ECG signals comprises the step of summing the first frequency response of the first ECG pulse with the second frequency response of the second ECG pulse to obtain a summed frequency response;

wherein the step of determining the late potentials from the combined ECG signals comprises the steps of;

measuring an amplitude of the summed frequency response in a predetermined frequency range to obtain a measured amplitude; and

comparing the measured amplitude with a predetermined maximum amplitude, wherein a late potential occurs where the measured amplitude exceeds the predetermined maximum amplitude.