Fluorescent compound suitable for use in the detection of saccharides
First Claim
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1. A fluorescent compound of the following general formula:
- ##STR6## in which F represents a fluorophore, R is selected from the group consisting of lower aliphatic and aromatic functional groups, and n and m each is 0, 1 or 2 with n+m being 2 or 3.
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Abstract
Disclosed is a fluorescent compound of a molecular structure comprising a fluorophore, at least one phenylboronic acid moiety, and at least one amine-providing nitrogen atom where the nitrogen atom is disposed in the vicinity of the phenylboronic acid moiety so as to interact intermolecularly with the boronic acid. The compound emits fluorescence of a high intensity upon binding to saccharide(s), and is therefore suitable for use in the detection of saccharide(s).
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6 Claims
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1. A fluorescent compound of the following general formula:
- ##STR6## in which F represents a fluorophore, R is selected from the group consisting of lower aliphatic and aromatic functional groups, and n and m each is 0, 1 or 2 with n+m being 2 or 3.
- View Dependent Claims (2)
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3. A fluorescent compound of the following formula ##STR7##
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4. A fluorescent compound of the following general formula:
- ##STR8## in which F represents a fluorophore, R is selected from the group consisting of lower alliphatic and aromatic functional groups, and n and m each is 0, 1 or 2 with n+m being 2 or 3.
- View Dependent Claims (5)
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6. A fluorescent compound of the following formula ##STR9##
Specification
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Current AssigneeResearch Development Corporation Of Japan (Japan Science And Technology Agency)
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Original AssigneeResearch Development Corporation Of Japan (Japan Science And Technology Agency)
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InventorsSandanayake, Saman, James, Tony, Shinkai, Seiji
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Primary Examiner(s)KOSLOW, CAROL M
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Application NumberUS08/336,236Time in Patent Office512 DaysField of Search252/301.16, 252/301.22, 436/546, 436/800, 564/8US Class Current252/301.16CPC Class CodesC07F 5/025 Boronic and borinic acid co...C09K 11/06 containing organic luminesc...Y10S 436/80 Fluorescent dyes, e.g. rhod...
