Iodine barrier teat dip

• US 5,503,838 A
• Filed: 05/06/1994
• Issued: 04/02/1996
• Est. Priority Date: 04/15/1993
• Status: Expired due to Term

• Current Assignee: Ecolab, Inc.
• Original Assignee: Ecolab, Inc.
• Inventors: Schmidt, William, Ihns, Deborah A.
• Primary Examiner(s): Cintins, Marianne M.
• Assistant Examiner(s): Weddington, Kevin E.
• Application Number:
  US08/238,976
• Time in Patent Office: 697 Days
• Field of Search: 424/407, 424/667, 424/672
• US Class Current: 424/407
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/10 Macromolecular compounds
• CPC Class Codes: A01N 25/24 containing ingredients to enhance the sticking of the active ingredients
• CPC Class Codes: A01N 59/12 Iodine, e.g. iodophors; Compounds thereof
• CPC Class Codes: A61K 9/0041 Mammary glands, e.g. breasts, udder; Intramammary administration
• CPC Class Codes: A61P 15/14 for lactation disorders, e.g. galactorrhoea

Abstract

A protective aqueous antimicrobial film forming composition that can be applied to dairy animals to form a protective film. The film can be used to reduce the incidence of both contagious and environmental mastitis in dairy herds and can be formed from an aqueous composition that can contain a nonionic iodine complex, a polyvinyl alcohol composition, having a degree of hydrolysis greater than 92%, preferably greater than 98%, and a thickener. The aqueous mixture can be applied to udder and teats of dairy herds to form a protective coating that can prevent infection from staphlococcus, streptococcus, klebsiella and other pathogens. The film can be removed using water in a convenient short period of time permitting efficient milking operations. After milking, the composition can be reapplied to the herd and can protect the herd from mastitis until the herd is again milked. The material of the invention has the property that after application and drying both films and plugs of the protective coating is softened and removed even in cold water in a convenient time frame.

Claims

1. An aqueous protective antimicrobial film forming composition, formulated to reduce the incidence of both contagious mastitis and environmental mastitis in a dairy herd, said composition consisting essentially of, in an aqueous base:

(a) an effective film forming amount of a polyvinyl alcohol composition having a degree of hydrolysis greater than 98.5%;

(b) an effective amount of a polymeric thickener composition; and

(c) an effective antimicrobial amount of an antimicrobial iodine-nonionic complex composition;

wherein a film formed from the protective composition can be substantially removed from the treated animal in less than 5 minutes.

2. The composition of claim 1 wherein the polyvinyl alcohol has a molecular weight between about 15,000 and 100,000.

3. The composition of claim 1 wherein the antimicrobial iodine-nonionic complex composition is a complex formed from a polymeric nonionic composition, comprising ethylene oxide, propylene oxide or mixtures thereof, and iodine.

4. The composition of claim 3 wherein the polymeric composition is a polyethylene oxide block, a polypropylene oxide block or a copolymeric segment comprising an ethylene oxide block and a propylene oxide block.

5. The composition of claim 4 wherein the polymeric composition is polyethoxylated alkyl phenol.

6. The composition of claim 1 wherein the thickener is a xanthan thickener.

7. The composition of claim 6 wherein there is about 1 to 10 wt. % of the polyvinyl alcohol and about 0.1 to 1 wt. % of the xanthan thickener.

8. The composition of claim 3 wherein there is about 1 to 12 wt % of the iodine-nonionic complex composition.

9. A method for reduction of contagious mastitis and environmental mastitis in a dairy herd, the method comprising:

(a) applying an aqueous protective antimicrobial film forming composition to an animal in a dairy herd comprising;

(i) an effective film forming amount of a polyvinyl alcohol composition with a degree of hydrolysis greater than about 92 wt %;

(ii) an antimicrobial amount of an iodine-nonionic complex composition; and

(iii) a thickener;

to form a film on the teat and a plug on the teat end; and

(b) when needed, removing said film and plug by contacting the teat with an aqueous wash, substantially removing the protective composition in less than 5 minutes, and wherein an effective amount of a colorant is optionally present in said composition.

10. The method of claim 9 wherein the film and plug are removed prior to milking, and after milking the animal is contacted with the protective composition.

11. The method of claim 9 wherein an effective amount of a colorant to indicate the presence of the composition is present.

12. The method of claim 9 wherein the polyvinyl alcohol has a molecular weight between about 15,000 and 100,000.

13. The method of claim 9 wherein the antimicrobial iodine-nonionic complex composition is a complex formed from a polymeric nonionic composition comprising ethylene oxide, propylene oxide or mixtures thereof, and iodine.

14. The method of claim 9 wherein the polymeric composition is a polyethylene oxide block, a polypropylene oxide block or a copolymeric segment comprising an ethylene oxide block and a propylene oxide block.

15. The method of claim 9 wherein the nonionic composition is an ethoxylated alkyl phenol.

16. The method of claim 9 wherein the thickener a xanthan thickener.

17. The method of claim 9 wherein there is about 1 to 10 wt. % of the polyvinyl alcohol and about 0.1 to 1 wt. % of the xanthan thickener.

18. The method of claim 9 wherein there is about 1 to 12 wt % of the iodine-nonionic complex composition.

19. An aqueous protective antimicrobial film forming composition consisting essentially of, in an aqueous base:

(a) about 0.5-10 wt % of a polyvinyl alcohol composition having a degree of hydrolysis greater than about 99.5%;

(b) about 0.1 to 1 wt % of an organic polymeric thickener; and

(c) about 1 to 12 wt % of an antimicrobial iodine-nonionic complex containing 0.1 to 1 wt % available iodine based on the final composition.

20. The composition of claim 19 wherein the iodine-nonionic complex is a complex of iodine and an ethoxylated alkyl phenol having 6-12 carbon atoms in the alkyl group and 5-20 moles of ethylene oxide.

21. The composition of claim 19 wherein the thickener is a xanthan thickener.