Analytical devices and methods of use thereof

• US 5,504,013 A
• Filed: 11/09/1994
• Issued: 04/02/1996
• Est. Priority Date: 11/12/1993
• Status: Expired due to Term

• Current Assignee: Inverness Medical Switzerland GmbH (Abbott Laboratories Incorporated)
• Original Assignee: Unipath Limited (Abbott Laboratories Incorporated)
• Inventors: Senior, Stephenie J.
• Primary Examiner(s): Housel, James C.
• Assistant Examiner(s): Soderquist, Arlen
• Application Number:
  US08/338,150
• Time in Patent Office: 510 Days
• Field of Search: 422/56, 422/58, 422/61, 436/169, 436/165
• US Class Current: 436/165
• CPC Class Codes: B01L 2300/042 Caps; Plugs
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/5023 with a sample being transported to, and subsequently stored in an absorbent for analysis
• CPC Class Codes: B01L 3/5029 using swabs
• CPC Class Codes: G01N 33/54366 Apparatus specially adapted for solid-phase testing

Abstract

An analytical device for determining the presence and/or concentration of an analyte in a sample liquid comprises a hollow casing; an assay strip within said casing for selectively capturing an analyte in sample liquid applied to the device; a bibulous sample liquid receiving member at or adjacent to a first extremity of said casing which collects sample liquid and transports it into the casing; a window in the casing at a location remote from the first extremity of the casing; and a single cap which can be applied in turn over the window during sample collection, and then over the sample receiving member.

Claims

1. An analytical device for determining the presence and/or concentration of an analyte in a sample liquid, comprising:

a) a hollow casing;

b) a bibulous sample liquid receiving member at or adjacent to a first extremity of said casing, said receiving member providing means for collecting sample liquid and transporting collected sample liquid into said casing;

c) means within said casing for selectively capturing said analyte in said collected sample liquid;

d) window means in said casing at a location remote from said first extremity of said casing, said window means enabling detection of said analyte to be effected from outside said casing; and

e) a single cover means engageable with said casing to enclose said bibulous sample receiving member and releasably engageable with said casing to enclose said window means, but not engageable with said casing to enclose both of said bibulous sample receiving member and said window means simultaneously.

2. An analytical device according to claim 1, wherein said cover means provides means for hand-holding said device while either of said bibulous sample receiving member and said window means are enclosed thereby.

3. An analytical device according to claim 1, wherein said casing is elongated and said first extremity is one end thereof.

4. An analytical device according to claim 3, wherein said cover means is telescopically receivable over each end of said elongate casing.

5. An analytical device according to claim 1, wherein said window means is located in a portion of said casing which is cooperatively engageable with means for reading the result of the analysis, said cooperatively engageable portion becoming exposed when said cover means is released to expose said window means.

6. An analytical device according to claim 1, wherein said bibulous sample receiving member protrudes from said casing.

7. A method of using an analytical device according to claim 1, wherein said device is hand-held by means of said cover means enclosing said window means, while said bibulous sample receiving member is introduced into a source of sample liquid, such as a urine stream, and thereafter said cover means is released to expose said window means.

8. A method according to claim 7, wherein after release of said cover means to expose said window means, the same cover means is used to enclose said bibulous sample receiving member.

9. A method according to claim 8, wherein following sample collection and enclosure of said bibulous sample receiving member, said device is hand-held by means of said cover means enclosing said bibulous sample receiving member to facilitate presentation of said window means to means for reading the result of said analysis.