Pacemaker mediated tachycardia response for VDD and VDDR modalities

• US 5,507,783 A
• Filed: 01/11/1995
• Issued: 04/16/1996
• Est. Priority Date: 01/11/1995
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Buchanan, Stuart W.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US08/372,273
• Time in Patent Office: 461 Days
• Field of Search: 607/14, 607/15, 128/697, 128/705
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions

Abstract

A pacemaker mediated tachycardia (PMT) is detected and suppressed in an implantable pacemaker operating in the VDD or VDDR modality. Such suppression is effectuated by extending the post ventricular atrial refractory period (PVARP) of the pacemaker to an extended PVARP that prevents retrograde P-waves from being tracked, thereby suppressing the PMT. The extended PVARP includes a retrograde window portion, following an absolute refractory portion. P-waves that occur during the retrograde window portion of the extended PVARP are deemed to be retrograde P-waves. The extended PVARP is returned to its original value whenever: (1) a P-wave is sensed following the extended PVARP, which P-wave is deemed to be a sinus P-wave, or (2) whenever a sufficient number of cardiac cycles elapse without the occurrence of a retrograde P-wave.

Claims

1. In a patient having an implanted pacemaker, a method for detecting and suppressing a pacemaker mediated tachycardia (PMT), the pacemaker including:

sensing means for sensing P-waves;

pulse generation means for generating a V-pulse; and

timing means for defining a PV delay that begins upon sensing a P-wave, after which a V-pulse is generated, whereby sensed P-waves are tracked with a V-pulse that occurs one PV delay thereafter, and a post ventricular atrial refractory period (PVARP) that begins following a V-pulse, and during which P-waves are not tracked, said method comprising the steps of;

detecting a PMT; and

suppressing the PMT in response to the detecting of the PMT, by;

increasing the PVARP of the pacemaker from an initial PVARP to an extended PVARP;

sensing if a P-wave occurs following the extended PVARP within at least one of a plurality of subsequent cardiac cycles; and

maintaining the PVARP at the extended PVARP in the absence of a P-wave being sensed following the extended PVARP;

restoring the PVARP to its initial PVARP in response to a P-wave being sensed following the extended PVARP within the at least one of the plurality of subsequent cardiac cycles.

2. The method of claim 1, wherein the step of increasing the PVARP comprises:

storing a V-P interval of one of a plurality of previous cardiac cycles;

adding a safety period to the V-P interval previously stored; and

defining the extended PVARP to be equal to the stored V-P interval plus the safety period.

3. The method of claim 2, wherein the adding of the safety-period includes adding at least 50 ms to the stored V-P interval.

4. The method of claim 2, wherein the storing of the V-P interval includes:

selecting a longest V-P interval from V-P intervals in at least a portion of the plurality of previous cardiac cycles; and

storing the longest selected V-P interval.

5. The method of claim 1, wherein the pacemaker further includes a counter, and wherein the suppression of the PMT further includes:

sensing a P-wave during the extended PVARP within the at least one of the plurality of subsequent cardiac cycles;

resetting a counter in response to the sensing of a P-wave during the extended PVARP within the at least one of the plurality of subsequent cardiac cycles;

incrementing the counter in response to an extended PVARP interval, within the plurality of subsequent cardiac cycles, during which a P-wave is not sensed, whereby the counter counts the absence of P-events during the extended PVARP;

determining whether a count maintained by the counter has reached a terminal count n; and

restoring the PVARP to the initial PVARP in response to determining that the count held in the counter has reached the terminal count n, whereby the PVARP is restored to its initial value whenever n cardiac cycles occur without a P-wave having been sensed during the extended PVARP.

6. The method of claim 5, wherein sensing a P-wave during the extended PVARP includes sensing a P-wave within a retrograde window portion of the extended PVARP, the retrograde window portion comprising a latter portion of the extended PVARP following an absolute refractory portion.

7. The method of claim 6, wherein detecting the PMT includes:

sensing a P-wave followed by a V-pulse within each of a plurality of previous cardiac cycles;

sensing if the plurality of previous cardiac cycles occurs at a rate in excess of a tachycardia reference rate (TRR);

measuring a V-P interval of at least one of the plurality of previous cardiac cycles, the V-P interval comprising the time period between a V-pulse and a next succeeding P-wave;

increasing a P-V interval in a single cardiac cycle following the plurality of previous cardiac cycles in the event the plurality of previous cardiac cycles occurs at a rate in excess of the TRR, the P-V interval comprising a time interval between a P-wave and a V-pulse within the single cardiac cycle;

measuring the V-P interval of the single cardiac cycle, the V-P interval comprising a time interval between a V-pulse and a P-wave within the single cardiac cycle;

sensing whether the V-P interval of the single cardiac cycle remains substantially unchanged from the V-P interval of the at least one of the plurality of previous cardiac cycles; and

concluding that a PMT is present when the V-P interval of the single cardiac cycle remains substantially unchanged.

8. In a patient having an implanted dual chamber pacemaker, a method for detecting and suppressing a pacemaker mediated tachycardia (PMT), the pacemaker including:

sensing means for sensing P-waves;

pulse generation means for generating a V-pulse; and

timing means for defining a PV delay that begins upon sensing a P-wave, after which a V-pulse is generated, whereby sensed P-waves are tracked by generating a V-pulse one PV delay thereafter, and a post ventricular atrial refractory period (PVARP) that begins following a V-pulse, and during which P-waves are not tracked, said method comprising the steps of;

determining if a PMT is present; and

suppressing the PMT by;

extending the PVARP of the pacemaker from an initial value to an extended value, whereby an extended PVARP is generated;

sensing the occurrence of a P-wave;

maintaining the PVARP at the extended PVARP in the absence of a P-wave being sensed following the extended PVARP;

restoring the PVARP to its initial value if;

(1) a P-wave is sensed following the extended PVARP within at least one of the plurality of subsequent cardiac cycles, or (2) a prescribed number of subsequent cardiac cycles elapse without a P-wave being sensed during the extended PVARP, whichever occurs first.

9. The method of claim 8, wherein the step of determining if a PMT is present comprises:

monitoring the P-waves and V-pulses of a recurring P-wave, V-pulse, P-wave, V-pulse, . . . sequence;

detecting whether a V-P time interval of such sequence remains stable in the face of a changing PV delay;

detecting whether the V-pulses are generated at a rate that exceeds a tachycardia reference rate (TRR); and

if the V-P time interval remains stable, and if the V-pulses occur at rate that exceeds the TRR, then concluding that a PMT is present.

10. The method of claim 8, wherein the step of extending the PVARP includes dividing PVARP into two portions, a first portion of which comprises an absolute refractory portion during which P-waves are not sensed, and a second portion of which comprises a retrograde window during which P-waves may be sensed but not tracked, and further during which any P-wave that is sensed is deemed to be a retrograde P-wave.

11. The method of claim 10, wherein dividing the PVARP into an absolute refractory portion and a retrograde window comprises allocating at least the first 50 ms of the extended PVARP as the absolute refractory portion and at least the last 150 ms of the extended PVARP as the retrograde window.

12. The method of claim 11, wherein the step of restoring the PVARP to its initial value whenever a prescribed number of subsequent cardiac cycles elapse without a P-wave being sensed during the extended PVARP comprises restoring the PVARP to its initial value whenever retrograde P-waves fail to occur during the retrograde window of the extended PVARP for a prescribed number of cardiac cycles n.

13. The method of claim 12, further including defining n, the number of cardiac cycles that must occur without a retrograde P-wave having been sensed before the extended PVARP is returned to its initial value, to be equal to at least one and no more than 255.

14. In a pacemaker having sensing and timing circuits, a method for detecting and suppressing a pacemaker mediated tachycardia (PMT), said method comprising the steps of:

detecting a PMT using the sensing and timing circuits of the pacemaker; and

suppressing the PMT once detected by;

increasing a post ventricular atrial refractory period (PVARP) of the pacemaker from an initial value to an extended PVARP;

sensing a P-wave during the extended PVARP within at least one of a plurality of subsequent cardiac cycles;

resetting a no-sensed-P-event (NSPE) count in response to the sensing of a P-wave during the extended PVARP within the at least one of the plurality of subsequent cardiac cycles;

incrementing the NSPE count in response to an extended PVARP interval, within the plurality of subsequent cardiac cycles, during which a P-wave is not sensed;

determining whether the NSPE count reaches a predefined terminal count;

restoring the PVARP to its initial value in response to determining that the NSPE count has reached the terminal count.

15. The method of claim 14, wherein the step of increasing the PVARP comprises:

storing a V-P interval of one of a plurality of previous cardiac cycles;

adding a safety period to the V-P interval having been stored; and

generating the extended PVARP by adding the safety period to the V-P interval having been stored.

16. The method of claim 15, wherein storing the V-P interval includes:

selecting a longest V-P interval from a plurality of V-P intervals associated with at least a portion of the plurality of previous cardiac cycles; and

storing the longest V-P interval having been selected.

17. The method of claim 16, wherein the step of increasing the PVARP comprises increasing the PVARP by a programmed amount of from 200 to 550 ms.

18. The method of claim 14, wherein the suppression of the PMT further includes:

sensing a P-wave following the extended PVARP within at least one of the plurality of subsequent cardiac cycles; and

restoring the PVARP to its initial value in response to the sensing of a P-wave following the extended PVARP within the at least one of the plurality of subsequent cardiac cycles.

19. An implantable dual-chamber pacemaker for detecting and suppressing a pacemaker mediated tachycardia (PMT) comprising:

detecting means for detecting a PMT; and

suppressing means for suppressing the PMT once detected, the suppressing means including;

PVARP extension means responsive to the PMT detecting means for extending a post ventricular atrial refractory period (PVARP) of the pacemaker from an initial value to an extended value, thereby creating an extended PVARP;

first sensing means for sensing a P-wave following the extended PVARP within at least one of a plurality of subsequent cardiac cycles; and

maintaining means for maintaining the PVARP at the extended PVARP in the absence of a P-wave being sensed following the extended PVARP;

restoring means for restoring the PVARP to its initial value in response to a P-wave being sensed by the first sensing means;

whereby a PMT is detected, suppressed and the PVARP is restored to its initial value.

20. The pacemaker of claim 19, wherein the PVARP extension means comprises:

means for detecting a V-P interval;

memory means for storing the V-P interval of one of a plurality of previous cardiac cycles, the memory means being coupled to the first sensing means;

adding means for adding a safety period to the V-P interval stored by the memory means; and

timing means responsive to the adding means for generating the extended PVARP to be equal to the safety period added to the stored V-P interval.

21. The pacemaker of claim 19, wherein the suppressing means further includes:

second sensing means for sensing a P-wave during the extended PVARP within the at least one of the plurality of subsequent cardiac cycles;

an incrementable coupled to the second sensing means, the counter being incremented in response to an extended PVARP interval, within the plurality of subsequent cardiac cycles, during which a P-wave is not sensed by the second sensing means;

reset means for resetting the counter in response to sensing a P-wave with the second sensing means; and

processing means coupled to the counter for determining whether the counter reaches a terminal count; and

the restoring means being coupled to the processing means and restoring the PVARP to its initial value whenever the counter reaches the terminal count.

22. The pacemaker of claim 19, wherein the PVARP extension means comprises means for dividing the PVARP into an absolute refractory portion followed by a retrograde time window, and wherein said second sensing means only senses P-waves that occur during the retrograde time window, the P-waves thus sensed by the second sensing means being considered as retrograde P-waves.

23. An implantable pacemaker for detecting and suppressing a pacemaker mediated tachycardia (PMT), said pacemaker comprising:

detecting means for detecting a PMT; and

PMT suppressing means responsive to the detecting means for suppressing the PMT, the PMT suppressing means including;

extension means for increasing a PVARP of the pacemaker from an initial value to an extended value, thereby creating an extended PVARP;

sensing means for sensing a P-wave during the extended PVARP within at least one of a plurality of subsequent cardiac cycles;

an incrementable counter coupled to the sensing means, the counter being incremented in response to an extended PVARP interval, within the plurality of subsequent cardiac cycles, during which a P-wave is not sensed by the sensing means;

reset means coupled to the counter for resetting the counter in response to the sensing of a P-wave during the extended PVARP within the at least one of the plurality of subsequent cardiac cycles;

processing means coupled to the counter and reset means for determining whether the counter reaches a terminal count;

restoring means for restoring the PVARP to its initial value in response to the processor means determining that the counter has reached a terminal count.

24. The pacemaker of claim 23, wherein the PMT suppressing means further includes:

second sensing means for sensing a P-wave following the extended PVARP within at least one of the plurality of subsequent cardiac cycles;

said restoring means restoring the PVARP in response to a P-wave being sensed by the second sensing means.