Catheter with perfusion system

• US 5,507,795 A
• Filed: 04/29/1994
• Issued: 04/16/1996
• Est. Priority Date: 04/29/1994
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Devices for Vascular Intervention, Inc. (Eli Lilly and Company)
• Inventors: Chiang, Andrew L., Schulz, Grace Y., Chang, Robert T., Krier, Jeffrey W., Hundertmark, Ron R.
• Primary Examiner(s): Brown, Michael A.
• Application Number:
  US08/236,485
• Time in Patent Office: 718 Days
• Field of Search: 606/79, 606/80, 606/86, 606/87, 606/88, 606/159, 606/167-169, 606/170-173, 606/180-181
• US Class Current: 606/167
• CPC Class Codes: A61B 17/320783 through side-hole, e.g. sliding or rotating cutter inside catheter
• CPC Class Codes: A61B 2017/00685 Archimedes screw
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22052 eccentric
• CPC Class Codes: A61B 2017/22069 Immobilising; Stabilising
• CPC Class Codes: A61M 2025/1097 with perfusion means for enabling blood circulation only while the balloon is in an inflated state, e.g. temporary by-pass within balloon

Abstract

Improved atherectomy catheters and methods of use are disclosed. The catheter includes a flexible body with a longitudinal passage therethrough. A housing is mounted at the distal end, with an elongated aperture formed in a lateral side. A drive cable is disposed in the passage of the catheter body, and a working element is disposed in the housing, attached to the distal end of the drive cable. Passages and openings are provided for flowing blood into the housing and for flowing blood from a proximal to a distal side of the cutting blade. An impeller can be provided proximal to the cutting blade to impel blood into the housing and past the blade. Blood flows through the housing and past the blade so as to perfuse tissue downstream from the device.

Claims

1. An atherectomy catheter comprising:

a catheter body having a distal end, a proximal end and a lumen therebetween;

a housing having a longitudinal axis, a hollow interior, a proximal end affixed to the distal end of the catheter body, a distal end, a perfusion port entry, a perfusion port exit, and an aperture on a lateral side of the housing;

a work element disposed in the housing;

a work element connector with a proximal end and a distal end, the connector disposed in the catheter body with the distal end affixed to the work element, the perfusion port entry being proximal the work element, the perfusion port exit being distal the work element; and

the housing defines at least one passage, the passage being in fluid communication with each perfusion port to facilitate perfusion of fluid through the housing and past the work element.

2. A catheter as set forth in claim 1, wherein the work element comprises a cutting blade movable in an axial direction, and wherein the affector connector comprises an axially translatable drive cable.

3. A catheter as set forth in claim 2, wherein the blade is rotatable, having a hollow interior, an open distal end, and a proximal end, the proximal end of the blade connected to the drive cable.

4. A catheter as set forth in claim 3, wherein the perfusion port exit includes a nose cone fixed to the distal end of the housing, the nose cone having hollow interior.

5. A catheter as set forth in claim 4, wherein the nose cone contains a mesh insert.

6. A catheter as set forth in claim 4, wherein the drive cable is coupled to a drive motor.

7. An atherectomy catheter as set forth in claim 4 wherein at least one passage is a groove on the interior surface of the housing.

8. A catheter as set forth in claim 4, wherein at least one passage is a slot in an outer surface of the cutting blade extending from the proximal end to the distal end thereof.

9. A catheter as set forth in claim 8, wherein the slot is parallel to the longitudinal axis.

10. A catheter as set forth in claim 8, wherein the slot is helical.

11. A catheter as set forth in claim 10, wherein the helical slot is configured to impel blood distally as the blade rotates.

12. A catheter as set forth in claim 8, wherein the blade is rotationally reciprocal and the slot is disposed within the portion of the blade that remains in contact with an interior wall of the housing.

13. A catheter as set forth in claim 4, wherein at least one passage is a tunnel extending through the blade from the proximal end to the distal end.

14. A catheter as set forth in claim 4, wherein an annular passage exists between the cutting blade and the housing.

15. A catheter as set forth in claim 14, wherein the cutting blade has a cross-sectional area in the range of 75% to 98% of the cross-sectional area of the interior of the housing.

16. A catheter as set forth in claim 4, wherein the perfusion port entry includes at least one opening in the catheter body, proximal to the aperture of the housing to facilitate fluid to enter the housing.

17. A catheter as set forth in claim 4, further comprising at least one opening in the catheter body or the housing, proximal to the aperture of the housing permitting fluid to flow in or out of the housing.

18. A catheter as set forth in claim 17, wherein the drive cable has an axial passage and at least one inlet hole near its distal end in communication with the axial passage, and the blade has an outlet hole on a distal side that is in communication with the axial passage, wherein fluid is permitted to flow through the axial passage.

19. A catheter as set forth in claim 17, wherein the distal end of the catheter body comprises a receiving space configured to receive at least a portion of the cutting blade, whereby the cutting blade is retractable proximal to the opening.

20. A catheter as set forth in claim 17, wherein the perfusion port exit includes at least one opening in the housing distal to the aperture of the housing to facilitate perfusion of fluid in or out of the housing.

21. A catheter as set forth in claim 17, further comprising an impeller blade fixed to the drive cable.

22. A catheter as set forth in claim 21, wherein the impeller blade is helical.

23. An atherectomy catheter for insertion into a blood vessel, comprising:

a catheter body having a distal end, a proximal end and a lumen therebetween;

a housing attached to the distal end of the catheter body, the housing has a perfusion port entry, a perfusion port exit, and a lateral side which defines an aperture for receiving stenotic material;

a work element moveably disposed in the housing, the work element defines a portion of at least one passage, the passage being in fluid communication between the perfusion port entry and the perfusion port exit to facilitate perfusion of fluid through the housing and past the work element; and

a drive cable, being disposed in the lumen of the catheter body, the drive cable has one end affixed to the work element for moving the work element,

whereby, when the catheter device inserts into a blood vessel, blood enters the housing through the perfusion port entry, flows through the passage, past the work element, and exits the housing past the work element through the perfusion port exit.

24. A device as set forth in claim 23, wherein the cable defines a portion of the passage, the cable includes an impeller blade to facilitate perfusion.

25. A device as set forth in claim 23, wherein the catheter body defines a portion of the perfusion port entry.

26. A device as set forth in claim 23, wherein the catheter has a nosecone, the perfusion port entry includes an aperture for drawing blood into the housing and the perfusion port exit includes outlet ports defined on the nosecone for facilitating perfusion of fluid.

27. A device as set forth in claim 23, wherein the perfusion port exit includes a nosecone attached to the housing, the nosecone includes a mesh insert to facilitate the perfusion of blood from the housing.

28. A device as set forth in claim 23, wherein the work element has a helical groove to define a portion of the passage.

29. A device as set forth in claim 23, wherein the work element connector has a central passage and holes, the work element is a cutter having a bore to define a portion of the passage of the housing.

30. A device as set forth in claim 23, wherein the passage of the work element includes slots.

31. A device as set forth in claim 23, wherein the passage of the work element includes tunnels.

32. A device as set forth in claim 23, wherein the housing includes a guide shaft.