Blood collection assembly having additive dispensing means and method for sample collection using same

• US 5,511,558 A
• Filed: 06/06/1994
• Issued: 04/30/1996
• Est. Priority Date: 06/06/1994
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Shepard, Thomas A., Vogler, Erwin A.
• Primary Examiner(s): RIMELL, SAMUEL G
• Application Number:
  US08/254,720
• Time in Patent Office: 694 Days
• Field of Search: 128/760, 128/761, 128/762, 128/763, 128/764, 604/403, 604/408, 604/411, 604/415
• US Class Current: 600/573
• CPC Class Codes: B01L 3/50825 Closing or opening means, corks, bungs closures for containers B65D; means for removing stoppers B67B7/02

Abstract

A blood collection assembly includes an evacuated container having an open end with a puncturable stopper therein. A receptacle in the container contains an additive and has an open end covered by a puncturable, non-resealable material.

In a method for preparing a blood sample for analysis, the stopper and receptacle covering are punctured by a cannula, the cannula is partially retracted into the receptacle so that blood drawn through the cannula contacts the additive and washes it directly into the container through a hole in the covering made by the cannula.

Claims

1. A blood collection assembly comprising;

a) a tube having a bottom wall and a side wall defining an open end;

b) a puncturable stopper sealably immobilized in said open end, said bottom wall, side wall and stopper enclosing an evacuated interior volume in said tube, said stopper comprising an annular upper portion and a lower skirt portion, said skirt portion defining a well;

c) a receptacle immobilized in said well, said receptacle comprising a side wall and a puncturable non-resealable bottom wall; and

d) an additive in said receptacle for use in analysis of blood.

2. The assembly of claim 1 wherein said receptacle is immobilized in said well by an interference fit between said skirt portion and the receptacle side wall.

3. The assembly of claim 1 wherein an upper edge of said receptacle side wall is in sealing contact with the annular upper portion of said stopper whereby said receptacle side wall and bottom wall and the stopper annular upper portion define an enclosed mixing chamber in the interior of said receptacle.

4. The assembly of claim 2 wherein said receptacle further comprises a puncturable top wall, said receptacle side wall, top wall and bottom wall defining an enclosed mixing chamber.

5. A method for preparing a blood sample for analysis using the assembly of claim 1 comprising;

a) puncturing said stopper and the bottom wall of said receptacle with a first end of a double ended cannula, a second end of said cannula being in fluid communication with a reservoir containing a blood sample to be analyzed, said puncturing defining a hole in said non-resealable bottom wall;

b) retracting said cannula through said hole but not through said stopper whereby blood is drawn by a pressure differential from said reservoir into the receptacle; and

c) allowing the blood drawn into the receptacle to contact the additive in the receptacle so that said blood and said additive flow through said hole into said tube.