Method of minimizing dead-periods in magnetic resonance imaging pulse sequences and associated apparatus

• US 5,512,825 A
• Filed: 11/25/1994
• Issued: 04/30/1996
• Est. Priority Date: 11/25/1994
• Status: Expired due to Term

• Current Assignee: Johns Hopkins University
• Original Assignee: Johns Hopkins University
• Inventors: Atalar, Ergin, McVeigh, Elliot R.
• Primary Examiner(s): O'Shea, Sandra L.
• Assistant Examiner(s): Haynes, Mack
• Application Number:
  US08/346,130
• Time in Patent Office: 522 Days
• Field of Search: 324/303, 324/307, 324/309, 324/318, 324/322
• US Class Current: 324/309
• CPC Class Codes: G01R 33/4833 using spatially selective excitation of the volume of interest, e.g. selecting non-orthogonal or inclined slices
• CPC Class Codes: G01R 33/561 by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences

Abstract

A method of minimizing dead-periods in magnetic resonance imaging pulse sequences employs a specimen disposed within magnetic field, a source of RF signals, a receiver for receiving signals from the specimen responsive to RF pulses and emitting respective output signals. A computer is provided for receiving the output signals from the receiver and establishing image information which may be displayed. For the dead-period, the minimum and maximum phase encoding step, the scan plane gradient pulse for the slice, phase encoding and readout directions are determined and the moments contained within the dead-period waveform is determined. The values are transformed into gradient amplifier coordinates and the minimum dead-period based on a dead-period waveform is determined. The dead-period is employed in establishing a hardware optimized waveform which may be trapezoidal. The trapezoidal waveform is preferably established by for each phase encoding step determining the starting and ending gradient levels and the moments contained within the dead-period waveform and employing the waveform to design a trapezoidal waveform using the calculated minimum dead-period. The method is particularly advantageous when employed in oblique magnetic resonance imaging. The method may also be employed with velocity-encoded or flow-compensated pulse sequences by employing first gradient moments in the information processing, in addition to the starting and ending gradient levels and the zeroeth moments. For other types of pulse sequences, the zeroeth moment and other higher moments may be employed. Associated apparatus is also disclosed.

Claims

1. A method of minimizing the duration of dead-periods in magnetic resonance imaging pulse sequences comprising

providing a specimen disposed within a main magnetic field, a source of pulsed RF signals, receiver means for receiving signals from said specimen responsive to said RF pulses and emitting responsive output signals, computer means for receiving said output signals from said receiver means and establishing image information related thereto and display means for displaying images from said imaging information,

determining for said dead-periods for the scan plane gradient pulse for the slice, phase encoding and readout directions determining the starting and ending gradient values and moments of the dead-period waveform,

transferring said values and moments to gradient amplifier coordinates,

determining minimum dead-periods from said gradient amplifier values, and

employing said minimum dead-periods to establish a hardware optimized waveform based upon said minimum dead-period values.

2. The method of claim 1 including

employing said scan plane determination to determine the maximum and minimum phase encoding steps for said dead-period.

3. The method of claim 2 including

determining the longest of said minimum dead-periods, and

employing the longest said minimum dead-period to establish said optimized waveform.

4. The method of claim 3 including

effecting transformation of said scan plane minimum dead-period values to gradient amplifier coordinates by multiplication by an oblique rotation matrix.

5. The method of claim 2 including

establishing said waveform by for each phase encoding step determining the starting and ending gradient levels and the zeroeth moments contained within the dead-period waveform,

transforming said values into gradient amplifier coordinates, and

employing said transformed gradient amplifier coordinates in determining said hardware optimized waveform.

6. The method of claim 5 including

employing said method to image an oblique plane.

7. The method of claim 6 including

effecting said minimum dead-period determination without regard to the shape of said dead-period waveform.

8. The method of claim 5 including

effecting said hardware optimized waveform determination without regard to the shape of said dead-period waveform.

9. The method of claim 5 including

employing each said hardware optimized waveform respectively on said gradient generating amplifiers.

10. The method of claim 5 including

employing said method while remaining within the amplifier gradient level and slew rate limitations of said gradient amplifiers.

11. The method of claim 5 including

employing said method in breath-hold cardiac imaging.

12. The method of claim 5 including

employing in minimum dead-period determination in addition to said scan plane gradient pulse, starting and ending gradient values and said zeroeth moment for said slice, phase encoding and readout directions, at least one higher moment of the dead-period gradient waveforms.

13. The method of claim 12 including

employing a trapezoidal waveform as said hardware optimized waveform.

14. The method of claim 13 including

in employing said minimum dead-periods to establish a trapezoidal waveform employing for each phase encoding step for slice, phase encoding and readout directions starting and ending gradient values, and the zeroeth and first moments of the dead-period gradient waveforms.

15. The method of claim 14 including

employing said method in processing at least one pulse sequence selected from the group consisting of velocity-encoded pulse sequences and flow-compensated pulse sequences.

16. The method of claim 12 including

in determining said dead-period after transformation of said scan plane coordinates to gradient amplifier coordinates employing hardware limitations in determining said minimum dead-period.

17. The method of claim 6 including

alter determining said hardware optimized waveform transforming said hardware optimized waveform to scan plane coordinates.

18. The method of claim 17 including

employing a trapezoidal waveform as said hardware optimized waveform.

19. The method of claim 18 including

employing the inverse of a rotation matrix in effecting said conversion to scan plane coordinates.

20. The method of claim 6 including

employing said method on a plurality of dead-periods within a gradient-echo pulse sequence.

35. The apparatus of claim 18 including

said apparatus being employable in breath-hold magnetic resonance cardiac imaging.

21. Apparatus for minimizing dead-periods in magnetic resonance imaging pulse sequences comprising

magnetic field generator means for establishing a main magnetic field on a specimen,

magnetic field gradient generating means for establishing gradients in said magnetic field,

RF signal generating means for emitting pulsed RF signals to at least a portion of said magnetic field passing through said specimen,

dead-period determining means for determining phase encoding steps by determining for the slice, phase encoding and readout directions, the pulse starting and ending gradient values and the moments contained within the dead-period waveform,

means for transforming these scan plane dead-period values and moments to gradient amplifier coordinates,

design waveform creating means for employing a dead-period determined by said dead-period determining means and establishing a hardware optimized waveform based thereon,

receiver means for receiving signals emitted from said specimen responsive to said RF pulses and emitting responsive output signals,

computer means for receiving said output signals from said receiver means and establishing image information related thereto, and

visual display means for displaying images from said image information received from said computer means.

22. The apparatus of claim 21 including

said dead-period determining means having means for determining the minimum and maximum said phase encoding steps.

23. The apparatus of claim 22 including

said dead-period determining means having means for determining the longest said minimum dead-periods, and

said design waveform creating means employing said longest minimum dead-period as said dead-period.

24. The apparatus of claim 23 including

said means for transforming including multiplication by a rotating matrix.

25. The apparatus of claim 21 including

said dead-period determining means having means for effecting said dead-period determination in oblique plane magnetic resonance imaging.

26. The apparatus of claim 24 including

said rotating matrix being an oblique plane rotating matrix.

27. The apparatus of claim 22 including

said design waveform creating means having means for establishing said design waveform for each phase encoding step for the slice, phase encoding and readout direction by determining the starting and ending gradient values and the moments contained within said dead-period waveform and transforming said dead-period values and moments into gradient amplifier coordinates and creating said hardware optimized waveform therefrom.

28. The apparatus of claim 21 including

said dead-period determining means and said design waveform creating means having means for effecting said determinations with respect to an oblique plane of said specimen.

29. The apparatus of claim 28 including

said dead-period determining means effecting said determination without regard to the shape of said dead-period waveform.

30. The apparatus of claim 29 including

said design waveform creating means effecting said hardware optimized waveform determination without regard to the shape of said dead-period waveform.

31. The apparatus of claim 30 including

said apparatus having means for employing each said hardware optimized waveform respectively on each said gradient generating amplifiers.

32. The apparatus of claim 30 including

said design waveform creating means creating said trapezoidal waveform which will remain within the gradient levels and slew rates of said amplifiers.

33. The apparatus of claim 21 including

said dead-period determining means having means for determining said phase encoding steps by determining a higher moment of said dead-period waveform for said slice, phase encoding and readout directions in addition to determining said starting and ending gradient values and the zeroeth moment.

34. The apparatus of claim 27 including

said design waveform means employing in establishing said hardware optimized waveform for each phase encoding step the starting and ending gradient values and moments for the slice, phase encoding and readout directions.

36. The apparatus of claim 33 including

said apparatus being employable with respect to at least one pulse sequence selected from the group consisting of velocity-encoded pulse sequences and flow-compensated pulse sequences.

37. The apparatus of claim 33 including

said higher moment being a first moment.

38. The apparatus of claim 28 including

said design waveform creating means having means for effecting said hardware optimized waveform as a trapezoidal waveform.

39. The apparatus of claim 28 including

said design waveform means having means for transforming said hardware optimized waveform to scan plane coordinates.

40. The apparatus of claim 39 including

said design waveform means employing the inverse of a rotation matrix in effecting said conversion to scan plane coordinates.