Reflectance sensor system

• US 5,513,642 A
• Filed: 10/12/1994
• Issued: 05/07/1996
• Est. Priority Date: 10/12/1994
• Status: Expired due to Fees

• Current Assignee: Rensselaer Polytechnic Institute
• Original Assignee: Rensselaer Polytechnic Institute
• Inventors: Ostrander, Lee E.
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US08/321,733
• Time in Patent Office: 573 Days
• Field of Search: 128/633, 128/664, 128/665, 356/39, 356/40, 356/41
• US Class Current: 600/334
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: G01N 21/49 within a body or fluid

Abstract

A method for determining the content of chemical constituents in a biological tissue medium includes providing a probe comprising a light source and a plurality of photodetector strips circumferentially arranged around the light source. A wavelength for the illumination of the light source is selected and the photodetector strips are illuminated at the selected wavelength. Voltage readings are then taken for each photodetector strip. After taking the readings, the probe is placed on a surface of the tissue medium and the medium is illuminated at the selected wavelength. Voltage readings are again taken at each photodetector strip. The voltage readings taken from the tissue medium are then adjusted by dividing these readings by the initial voltage readings for each photodetector strip. A logarithm is taken for the adjusted voltage readings as a function of the separation distance between each photodetector strip and the light source. The values from the logarithmic function may be filtered according to a formula in which a smoothing approximation is utilized. A theoretical model is used to determine the flux of photons incident on each of the photodetector strips. Parameters are used to minimize the mean squared error or other error function when comparing the model values to the measured values.

Claims

1. A method for determining the content of chemical constituents in a medium through light reflectance comprising the steps of:

providing a probe comprising a light source and a plurality of photodetector strips circumferentially spaced around the light source and at different separation distances between the light source and each photodetector strip;

selecting a wavelength for illumination of the photodetector strips;

uniformly illuminating the photodetector strips at the selected wavelength;

taking a test voltage reading from each photodetector strip;

placing the probe on a surface of the medium;

illuminating the medium at the selected wavelength using the light source;

taking a voltage reading from each photodetector strip;

adjusting the voltage reading from each photodetector strip by dividing the voltage reading by the test voltage reading from each photodetector strip;

taking the logarithm of the adjusted voltage reading where S'"'"'(r) is the logarithm of the adjusted voltage reading as a function of the separation distance r between each photodetector strip and the light source;

filtering values from the logarithmic function according to the formula;

##EQU3## where S(r) are the filtered values, r_i is the distance from the light source to a photodetector strip i and N is a value based on a smoothing approximation, including N=zero; and

using the filtered values as an indication of the content of chemical constituents in the medium.

2. The method according to claim 1, including theoretically determining a flux of photons reflected from the medium and incident on the photodetector strips according to the model:

##EQU4## where F(r) equals the flux, and (α

·

D) and K are values of parameters to minimize an error between the model and the filtered values.

3. The method according to claim 2, including comparing the filtered values to the model results.

4. The method according to claim 1, including providing the photodetector strips to be separated from the light source at a distance ranging from 2.5 to 34.5 mm.

5. The method according to claim 1, including providing the light source to be a light emitting diode (LED).