Cardiac arrhythmia detection system for an implantable stimulation device

• US 5,513,644 A
• Filed: 09/22/1994
• Issued: 05/07/1996
• Est. Priority Date: 12/01/1992
• Status: Expired due to Term

• Current Assignee: Siemens Pacesetter, Inc. (Abbott Laboratories)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories)
• Inventors: McClure, Kelly H., Bornzin, Gene A.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US08/310,687
• Time in Patent Office: 593 Days
• Field of Search: 128/696, 128/697, 128/702, 128/704, 128/705, 128/708, 128/901, 128/902, 607/4, 607/5, 607/14, 607/27
• US Class Current: 600/521
• CPC Class Codes: A61N 1/3702 Physiological parameters A61N1/365 takes precedence; evoked response A61N1/371
• CPC Class Codes: A61N 1/3704 Circuits specially adapted therefor, e.g. for sensitivity control
• CPC Class Codes: Y10S 128/901 Suppression of noise in electric signal

Abstract

A cardiac event and arrhythmia detection system and method detects arrhythmic cardiac activity or other information from an electrogram signal of a heart. The system senses the electrogram signal through an electrogram lead, preliminarily processes the signal, and converts it to a plurality of discrete digital signals, each of which represents the magnitude of the electrogram signal at a prescribed sample time. The discrete digital signals are applied to both a cardiac event detector and a morphology detector. The morphology detector detects selected changes in the morphology (shape) of the electrogram signal, wherein such changes automatically control the sensitivity (gain and/or threshold) used to detect cardiac events. The occurrence of a prescribed amount of change in the detected morphology over time indicates the occurrence of a prescribed arrhythmic cardiac condition.

Claims

1. An implantable cardiac event detection system for eliminating sensing of high amplitude T-waves, the system including an implantable lead that transmits an electrogram signal from a heart, comprising:

an amplifier, coupled to the implantable lead, for amplifying an electrogram signal;

threshold detection means, coupled to the amplifier, for detecting an occurrence of an R-wave in the electrogram signal whenever the magnitude of the electrogram signal exceeds a threshold value; and

control means, responsive to the detection of the R-wave, for dynamically changing the threshold value from an initial value to a temporary value, and then gradually returning the threshold value from the temporary value back to the initial value within a prescribed time period, the prescribed time period being selected to return the threshold value to its initial value prior to the occurrence of a successive R-wave, the prescribed time period being automatically adjusted as a function of heart rate, so that a high amplitude T-wave that follows the R-wave is not sensed.

2. The implantable cardiac event detection system, as set forth in claim 1, wherein:

the control means changes the threshold value from the temporary value back to the initial value in a predetermined stepwise fashion.

3. The implantable cardiac event detection system, as set forth in claim 1, further comprising:

means for maintaining the threshold value at the temporary value for a programmable time period before changing the threshold value from its temporary value back to its initial value.

4. The implantable cardiac event detection system, as set forth in claim 1, further comprising:

means for programmably selecting a plurality of programmable parameters, at least one of the initial threshold value or the temporary threshold value being included in the plurality of programmable parameters.

5. The implantable cardiac event detection system, as set forth in claim 1, wherein the control means comprises:

amplitude detecting means for detecting an amplitude value of the R-wave;

averaging means for determining an average amplitude value over a predetermined number of previous cardiac cycles; and

means for setting the initial threshold value and the temporary value as a percentage of the average amplitude value determined by the averaging means.

6. The implantable cardiac event detection system, as set forth in claim 5, wherein:

the averaging means includes means for determining an average baseline value of the electrogram signal, the average baseline value corresponding to a noise signal; and

the initial threshold value includes the sum of the average baseline value and a prescribed percentage of the average amplitude value, whereby the event detector detects only R-waves which are above the noise signal.

7. The implantable cardiac event detection system, as set forth in claim 5, wherein the amplitude detecting means comprises:

a maximum detecting means for detecting a maximum value of the electrogram signal, the maximum value being the most positive value above a baseline value.

8. The implantable cardiac event detection system, as set forth in claim 5, wherein the amplitude detecting means comprises:

a peak detecting means for detecting a peak value of the electrogram signal.

9. The implantable cardiac event detection system, as set forth in claim 8, wherein the peak detecting means comprises:

a minimum detecting means for detecting a minimum value of the electrogram signal, the minimum value being the most negative value below a baseline value;

a maximum detecting means for detecting a maximum value of the electrogram signal, the maximum value being the most positive value above the baseline value; and

means for comparing an absolute value of the minimum value with an absolute value of the maximum value and for defining the peak value as the absolute value of the minimum value or the maximum value, whichever is larger.

10. An implantable cardiac event detection system for eliminating sensing of high amplitude T-waves, the cardiac event detection system including an implantable lead that transmits an electrogram signal from a heart, comprising:

an amplifier, coupled to the implantable lead, for amplifying an electrogram signal;

threshold detection means, coupled to the amplifier, for detecting an occurrence of an R-wave in the electrogram signal whenever the magnitude of the electrogram signal exceeds a threshold value; and

control means, responsive to the detection of the R-wave, for dynamically changing the threshold value from an initial value to a temporary value, for maintaining the threshold value at the temporary value for a programmable time period, and then for gradually returning the threshold value from the temporary value back to the initial value in a predetermined stepwise fashion within a prescribed time period, the prescribed time period being selected to return the threshold value to its initial value prior to the occurrence of a succesive R-wave, so that a high amplitude T-wave that follows the R-wave is not sensed.

11. The implantable cardiac event detection system, as set forth in claim 10, wherein the control means comprises:

means for automatically adjusting the prescribed time period as a function of heart rate.

12. The implantable cardiac event detection system, as set forth in claim 10, wherein the control means further comprises:

amplitude detecting means for detecting an amplitude value of the R-wave;

averaging means for determining an average amplitude value over a predetermined number of previous cardiac cycles; and

means for setting the initial threshold value, the temporary value and the gain of the amplifier as a function of the average amplitude value.

13. An implantable cardiac event detection system for eliminating sensing of high amplitude T-waves, the system including an implantable lead that transmits an electrogram signal from a heart, comprising:

an amplifier, coupled to the implantable lead, for amplifying an electrogram signal;

threshold detection means, coupled to the amplifier, for detecting an occurrence of an R-wave in the electrogram signal whenever the magnitude of the electrogram signal exceeds a threshold value; and

control means, responsive to the detection of the R-wave, for dynamically changing the threshold value from an initial value to a temporary value, and then for returning the threshold value from the temporary value to the initial value in accordance with an adjustable recovery curve so that a T-wave that follows an R-wave is not sensed.

14. The implantable cardiac event detection system, as set forth in claim 13, wherein the control means comprises:

means for adjusting at least a first and a second parameter which define the adjustable recovery curve, the first parameter being a delay period which maintains the threshold value at its temporary value for a predetermined period of time, and the second parameter being a slope which defines the rate of return from the temporary value to the initial value.

15. The implantable cardiac event detection system, as set forth in claim 14, wherein the control means comprises:

means for adjusting the slope in a predetermined stepwise fashion.

16. The implantable cardiac event detection system, as set forth in claim 14, further comprising:

means for programmably selecting a plurality of programmable parameters, at least one of the slope or the delay period being included in the plurality of programmable parameters.

17. The implantable cardiac event detection system, as set forth in claim 13, further comprising:

means for programmably selecting a plurality of programmable parameters, at least one of the initial threshold value or the temporary threshold value being included in the plurality of programmable parameters.

18. The implantable cardiac event detection system, as set forth in claim 13, wherein the control means comprises:

amplitude detecting means for detecting an amplitude value of the R-wave;

means for determining an average baseline value of the electrogram signal;

averaging means for determining an average amplitude value over a predetermined number of previous cardiac cycles; and

means for setting the initial threshold value and the temporary value as a prescribed percentage of the sum of the average baseline value and the average amplitude value.

19. An implantable cardiac event detection system for eliminating sensing of high amplitude T-waves, the system including an implantable lead that transmits an electrogram signal from a heart, comprising:

an amplifier, coupled to the implantable lead, for amplifying an electrogram signal, the amplifier having a plurality of programmable gains;

first control means for automatically adjusting the gain of the amplifier so that the electrogram signal is within an optimum dynamic range even in the presence of changing cardiac signal morphology such that an R-wave within the electrogram signal is not clipped and a T-wave is proportionally reduced relative to the R-wave;

threshold detection means, coupled to the amplifier, for detecting an occurrence of an R-wave in the electrogram signal whenever the magnitude of the electrogram signal exceeds a threshold value; and

second control means, responsive to the detection of the R-wave, for dynamically changing the threshold value from an initial value to a temporary value, and then for gradually returning the threshold value from the temporary value to the initial value prior to the occurrence of a successive R-wave;

whereby a T-wave that follows the R-wave is not sensed.

20. An implantable cardiac event detection system, the system including an implantable lead that transmits an electrogram signal from a heart, comprising:

sensing means, coupled to the implantable lead, for sensing an R-wave in the electrogram signal, the sensing means having a gain factor which can be programmably adjusted;

means, coupled to the sensing means, for determining a baseline value of the electrogram signal; and

amplitude detecting means, coupled to the sensing means, for detecting an amplitude value of the R-wave;

means for automatically adjusting the gain factor of the sensing means based on the difference between the amplitude value of the R-wave and the baseline value;

threshold detection means, coupled to the sensing means, for detecting an occurrence of an R-wave in the electrogram signal whenever the magnitude of the electrogram signal exceeds a threshold value;

control means, responsive to the detection of the R-wave, for dynamically changing the threshold value from an initial value to a temporary value, and then for gradually returning the threshold value from the temporary value back to the initial value prior to the occurrence of a successive R-wave, the initial value and the temporary value each being automatically adjusted as a function of the average baseline value and the average amplitude value;

whereby a T-wave that follows the R-wave is not sensed as a result of the adjustment of the gain factor of the sensing means and as a result of the temporary threshold value being adjusted above the T-wave amplitude even in the presence of changing cardiac morphology.