Apparatus for preventing cross-contamination of multi-well test plates
First Claim
1. An assembly for simultaneously confining multiple samples in separate chambers during thermal equilibration, comprising:
- a plate defining a plurality of containment wells, each well having an opening at a principal surface of said plate;
a compressible gasket disposed on and extending over the majority of said principal surface of said plate, said compressible gasket having a plurality of holes in register with said wells; and
a lid disposed on said compressible gasket, said lid having a surface for compressing said compressible gasket on said principal surface of said plate to form a seal and close said wells to define individual closed well chambers, thereby preventing said samples from flowing from one well chamber to another between said lid and said principal surface of said plate during thermal equilibration.
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Accused Products
Abstract
A multi-well plate which prevents cross-contamination of specimens through the use of a resilient gasket which covers a majority of the top of the plate and is compressed by a lid. It thus provides a sealing assembly for arrays of containers of any size or shape. A multi-well plate of modular construction is also disclosed in which resilient gaskets prevent cross-contamination of samples. The gaskets may be unitary sheets with or without an array of openings corresponding to the well openings or may consist of discrete single-cell gaskets. A multi-well plate in which the wells have conical ends is also provided.
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Citations
6 Claims
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1. An assembly for simultaneously confining multiple samples in separate chambers during thermal equilibration, comprising:
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a plate defining a plurality of containment wells, each well having an opening at a principal surface of said plate; a compressible gasket disposed on and extending over the majority of said principal surface of said plate, said compressible gasket having a plurality of holes in register with said wells; and a lid disposed on said compressible gasket, said lid having a surface for compressing said compressible gasket on said principal surface of said plate to form a seal and close said wells to define individual closed well chambers, thereby preventing said samples from flowing from one well chamber to another between said lid and said principal surface of said plate during thermal equilibration. - View Dependent Claims (2, 3, 4, 5, 6)
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Specification