Compositions, methods and apparatus for inhibiting fogging of endoscope lenses

• US 5,518,502 A
• Filed: 06/08/1994
• Issued: 05/21/1996
• Est. Priority Date: 06/08/1994
• Status: Expired due to Term

• Current Assignee: United States Surgical Corporation (Medtronic Plc)
• Original Assignee: United States Surgical Corporation (Medtronic Plc)
• Inventors: Zinner, Darren E., Stone, Corbett W., Muth, Ross R., Kaplan, Donald S., Totakura, Nagabhushanam
• Primary Examiner(s): Apley, Richard J.
• Assistant Examiner(s): FLANAGAN, BEVERLY MEINDL
• Application Number:
  US08/255,520
• Time in Patent Office: 713 Days
• Field of Search: 128/4, 128/6, 604/1, 604/264, 15/210.01, 15/214, 15/220.4, 15/244.1, 600/153, 600/155, 600/156, 600/157, 600/158, 600/169
• US Class Current: 600/157
• CPC Class Codes: A61B 1/126 provided with means for cleaning in-use
• CPC Class Codes: A61B 1/127 with means for preventing fogging A61B1/253 takes precedence

Abstract

Methods for preventing and/or eliminating fogging of endoscope lenses during an endoscopic procedure which include the steps of introducing an endoscope into a body cavity and contacting the endoscope lens with a biocompatible and biodegradable composition containing a polyalkylene oxide while the lens is positioned within the body. Alternatively, the endoscope may be coated with a biocompatible polyHEMA coating which is activated by a biocompatible solution, such as water or saline, which may be introduced during use through a fluid conduit on the endoscope. Devices for preventing and/or eliminating fogging of endoscope lenses during endoscopic procedures and conveying antifogging solutions to the distal end of the endoscope are also provided, and may include a distensible applicator.

Claims

1. A method for eliminating fogging of an endoscope lens which comprises:

introducing a distal end portion of an endoscope into a body;

passing a fluid composition comprising polyalkylene oxide through a conduit in the endoscope; and

contacting a lens associated with said distal end portion of said endoscope with the composition comprising polyoxyalkylene which has been passed through the conduit while said lens remains within the body.

2. The method according to claim 1, wherein said polyoxyalkylene is selected from the group consisting of homopolymers, copolymers and blends of polypropylene oxide and polyethylene oxide.

3. The method according to claim 1, wherein said polyoxyalkylene comprises a polyoxypropylene-polyoxyethylene block copolymer.

4. The method according to claim 3, wherein said polyoxypropylene-polyoxyethylene block copolymer has a molecular weight of from about 8,000 to about 13,000.

5. The method according to claim 1, wherein said polyoxyalkylene is present in an amount of about 0.01 to about 5 weight percent of said composition.

6. The method according to claim 1, wherein said composition further comprises a biocompatible solvent selected from the group consisting of water and saline solution.

7. A surgical apparatus comprising:

a) an endoscope having an elongated insertion member;

b) at least one lens disposed adjacent a distal end of said member;

c) a reservoir containing an antifogging solution comprising polyalkylene oxide, said reservoir being operatively associated with said member; and

d) means for selectively directing a quantity of said solution comprising polyalkylene oxide from said reservoir to said at least one lens while said distal end of said endoscope is positioned within a body.

8. The surgical apparatus as recited in claim 7, wherein said reservoir is disposed within said elongated insertion member.

9. The surgical apparatus as recited in claim 7, wherein said directing means further comprises an outlet for directing a spray of said solution toward said at least one lens, said outlet being movable from a first position within said elongated insertion member to a second extended position distal said lens.

10. A surgical apparatus comprising:

an endoscope having a distal end and a proximal end and a lens disposed at said distal end having an exposed distal surface, said distal lens surface being coated with a composition comprising polyHEMA; and

a conduit for conveying fluid from said proximal end to said distal end and directing said fluid onto at least a portion of said distal lens surface.

11. The surgical apparatus according to claim 10 wherein said fluid is water.

12. The surgical apparatus according to claim 10 wherein said fluid is saline solution.

13. The surgical apparatus according to claim 10 wherein said conduit has an outlet end movable from a first position not extending beyond the distal end of said endoscope to a second position extending beyond the distal end of said endoscope.

14. The surgical apparatus according to claim 10 wherein said endoscope is contained in a sterile package.

15. A method of preventing fogging of an endoscope comprising:

coating the distal lens of an endoscope with a solution of polyHEMA;

drying the solution to form a polyHEMA coating on the distal lens;

inserting the endoscope into a mammalian body;

applying antifogging solution to the distal lens surface through a fluid conduit on the endoscope.

16. The method of claim 15 wherein said step of coating the distal lens with a solution of polyHEMA comprises coating the distal lens with a solution of from about 0.1 to about 25 percent polyHEMA.

17. The method of claim 15 wherein said step of coating the distal lens with a solution of polyHEMA comprises coating the distal lens with a solution of from about 1 to about 5 percent polyHEMA.

18. The method of claim 15 wherein said step of coating the distal lens with a solution of polyHEMA comprise coating the distal lens with a solution of from about 2 to about 3 percent polyHEMA.

19. The method of claim 15 wherein said step of coating the distal lens with a solution of polyHEMA comprises coating the distal lens with polyHEMA in ethanol.

20. The method of claim 15 wherein said step of applying an antifogging solution to the distal lens surface comprises applying an antifogging solution selected from the group consisting of water, saline and polyoxyalkylene.

21. The method of claim 15 further comprising the following steps after said drying step and prior to said inserting step:

packaging said endoscope with the polyHEMA coating on the distal lens surface in a package;

sterilizing said packaged endoscope; and

removing said packaged sterile endoscope from the package.

22. The method of claim 15 further comprising the following steps after said drying step and prior to said inserting step:

sterilizing said endoscope with said polyHEMA coating on said distal lens surface.