Biomedical electrodes containing solid state conductive polymer compositions

• US 5,520,180 A
• Filed: 09/27/1994
• Issued: 05/28/1996
• Est. Priority Date: 11/15/1991
• Status: Expired due to Term

• Current Assignee: 3M Company
• Original Assignee: 3M Company
• Inventors: Dietz, Timothy M., Uy, Rosa
• Primary Examiner(s): Cohen, Lee S.
• Application Number:
  US08/312,707
• Time in Patent Office: 609 Days
• Field of Search: 128/638-641, 607/142, 607/149, 607/152, 607/153, 606/32, 604/20, 252/500, 524/386
• US Class Current: 600/397
• CPC Class Codes: A61B 2562/0215 Silver or silver chloride containing
• CPC Class Codes: A61B 5/259 using conductive adhesive means, e.g. gels
• CPC Class Codes: A61B 5/268 containing conductive polymers, e.g. PEDOT:PSS polymers
• CPC Class Codes: Y10S 526/931 Pressure sensitive adhesive

Abstract

Solid state conductive polymer compositions which are ionically-conductive regardless of the amount of water present in the composition are disclosed. The compositions have solvating polymer, ionic salt, and optionally if the composition is not cohesive and pliable, essentially non-volatile plasticizer in an amount sufficient to render the composition cohesive and pliable. Biomedical electrodes having means for electrical communication contacting the compositions are also disclosed. Methods of making the compositions and electrodes are also disclosed.

Claims

1. A biomedical electrode, comprising:

(a) a conductive medium comprising a solid state conductive polymer composition; and

(b) means for electrical communication interacting between said conductive medium and electrical equipment;

wherein the solid state conductive polymer composition comprises

(a) an ionically conductive polymer electrolyte complex formed by a process where the complex is effectively dehydrated by essentially evaporating water, and

(b) optionally if the complex is not cohesive and pliable, an essentially non-volatile plasticizer present in an amount sufficient to render the composition cohesive and pliable;

said polymer electrolyte complex comprising a solid solution of an ionic salt dissolved in a solvating polymer wherein the complex is ionically conductive after processing;

said solvating polymer is selected from the group consisting of crosslinked poly(N-vinyl lactam);

crosslinked polyacrylamide and its ionic forms;

crosslinked polyacrylic acid and its salts;

crosslinked poly(2-acrylamide-2-methylpropane sulfonic acid), its salts, crosslinked copolymers of the acid, crosslinked copolymers of salts of the acids, or mixtures thereof; and

combinations thereof.

2. The biomedical electrode according to claim 1, wherein said electrical communication means comprises a conductor member having a conductive interface portion contacting said conductive medium and a tab portion not contacting said conductive medium.

3. The biomedical electrode according to claim 1, wherein the means for electrical communication comprises a conductor member having an eyelet or snap connector contacting the conductive medium.

4. The biomedical electrode according to claim 1, and wherein the plasticizer is present in an amount of from about 65 to about 95 weight percent of the composition to form a cohesive, pliable and pressure-sensitive adhesive composition.

5. The biomedical electrode according to claim 1, wherein said solvating polymer is crosslinked poly(N-vinyl lactam) present in an amount of from about 5 to about 50 weight percent of the composition and wherein said plasticizer is present in an amount of from about 50 to about 90 weight percent of the composition.

6. The biomedical electrode according to claim 5, wherein said poly(N-vinyl lactam) is crosslinked poly(N-vinyl pyrrolidone) present in an amount of from about 20 to about 45 weight percent and wherein said plasticizer is a polyhydric alcohol present in an amount of from about 50 to about 75 weight percent.

7. The biomedical electrode according to claim 6, wherein said polyhydric alcohol comprises glycerin, polyethylene glycol, or mixtures thereof.

8. The biomedical electrode according to claim 6, wherein said ionic salt comprises lithium chloride, lithium perchlorate, sodium citrate, potassium chloride, or mixtures thereof present in an amount of from about 0.5 to about 5 weight percent of the composition.

9. The biomedical electrode according to claim 6, wherein said ionic salt is potassium chloride present in an amount of from about 2 to about 3 weight percent of the composition.

10. The biomedical electrode according to claim 9, wherein said polyhydric alcohol is polyethylene glycol present in an amount of about 65 weight percent of the composition and wherein the composition is pressure sensitive adhesive.

11. The biomedical electrode according to claim 1, further comprising an iontophoretically active pharmaceutical associated with the composition.