Method and apparatus for lowering the intraocular pressure of an eye

• US 5,520,631 A
• Filed: 07/22/1994
• Issued: 05/28/1996
• Est. Priority Date: 07/22/1994
• Status: Expired due to Term

• Current Assignee: Wound Healing of Oklahoma
• Original Assignee: Wound Healing of Oklahoma
• Inventors: Li, Bing, Nordquist, Robert E.
• Primary Examiner(s): JONES, MARYBETH O
• Application Number:
  US08/279,506
• Time in Patent Office: 676 Days
• Field of Search: 623/4, 604/8-10, 604/289, 604/294
• US Class Current: 604/8
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: Y10S 623/905 Eye

Abstract

A method and apparatus for lowering the intraocular pressure of an eye is disclosed and claimed. In the method of the invention, an opening is created in the limbus corneae region of the eye. A filtering implant having a foot portion and a body portion is provided for implantation. The foot portion of the implant is placed through the limbal opening into the anterior chamber of the eye, and the body portion is buried beneath a scleral flap. The apparatus of the invention is a filtering implant comprising a cellulosic membrane adapted to extend from the anterior chamber of the eye to a drainage area. Besides its draining function, the apparatus inhibits wound healing by occupying the space of the limbal opening. In its preferred embodiment, the implant comprises a goblet-shaped glucose homopolymer membrane having foot, neck and body portions. The foot portion of the membrane is of a general rectangular shape, while the body portion is bell-shaped. The neck segment connects the foot portion to the body portion.

Claims

1. A method for lowering the intraocular pressure of an eye, which comprises:

(a) creating an opening in the limbus corneae that is about 2.5 mm-3 mm wide to provide access to the anterior chamber of said eye;

(b) providing a filtering implant, said implant being generally rectangular in shape and having two side notches defining a foot portion and a body portion, said foot portion measuring approximately 1 mm (length)×

6 mm (width);

(c) placing said foot portion through said opening into said anterior chamber; and

(d) completely burying said body portion in a surgical bed beneath a scleral flap to a depth between 50 and 70 percent of the scleral thickness.

2. The method according to claim 1, wherein said foot is placed into said anterior chamber at a point anterior to the trabecular meshwork.

3. The method according to claim 1, wherein said implant is center cut through said foot portion.

4. The method according to claim 1, wherein said opening is created by excising a section of the scleral wall at the 1:

00 o'"'"'clock position.

5. The method according to claim 1, wherein said implant comprises a cellulosic membrane.

6. A method for lowering the intraocular pressure of an eye, which comprises:

(a) thoroughly rinsing a cellulosic membrane in distilled water;

(b) heating said cellulosic membrane to 100°

C. for 30 minutes in 2% sodium bicarbonate and 1% ethylenediaminetetraacetic acid;

(c) cooling said cellulosic membrane at 4°

C. in 2% formaldehyde or balanced saline solution;

(d) rinsing said cellulosic membrane in a balanced saline solution;

(e) cutting said cellulosic membrane into a generally rectangular shape having altered margins so as to form a foot portion and a body portion;

(f) creating an opening in the limbus corneae;

(g) placing said foot portion through said opening into the anterior chamber of said eye; and

(h) burying said body portion beneath a scleral flap.

7. The method according to claim 6, wherein said opening is about 2.5 mm-3 mm wide.

8. The method according to claim 6, wherein said foot portion measures approximately 1 mm (length)×

6 mm (width).

9. The method according to claim 6, wherein said implant has a thickness of approximately 0.15 mm.

10. The method according to claim 6, wherein said implant is buried to a depth between 50 and 70 percent of the scleral thickness.