Two-component device for the administration of drugs

• US 5,520,642 A
• Filed: 03/23/1995
• Issued: 05/28/1996
• Est. Priority Date: 03/24/1994
• Status: Expired due to Term

• Current Assignee: Dibra - Fundo De Investimento Em Participações.
• Original Assignee: Dibra - Fundo De Investimento Em Participações.
• Inventors: Grillenzoni, Gianni, Landi, Mauro, Bigagli, Roberto, Arcari, Augusto
• Primary Examiner(s): YASKO JR, JOHN D
• Application Number:
  US08/409,351
• Time in Patent Office: 432 Days
• Field of Search: 604/89, 604/88, 604/187, 604/203, 604/200, 604/201, 604/218, 604/232, 604/905, 604/87, 604/86
• US Class Current: 604/88
• CPC Class Codes: A61M 5/2429 by telescoping of ampoules or carpules with the syringe body
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence

Abstract

This invention refers to a device for the administration of aqueous solutions or suspensions of drugs or diagnostic agents including, for instance, contrast media for X-ray, magnetic resonance and ultrasound procedures. In particular this invention refers to a two-component device, substantially constituted by: a) a piston-container, which is prefilled with an injectable solution/suspension, and sealed by a stopper-plunger, b) a housing-barrel, provided with collecting and administration systems. Said components a) and b) are combined together only when used, ensuring the preparation sterility.

Claims

1. A device for the administration of aqueous solutions and suspensions of drugs and diagnostic agents comprising a first element (14) and a second element (1), to be coupled one to the other when used, wherein:

the first element (14) comprises a container for fluids (15), a stopper-plunger (16) sealing said container, said stopper-plunger being opened to the flow of a fluid through a piercable baffle (21) and being slidable inside said container (15), in order to produce the outlet of the fluid contained in it,

the second element (1) is a housing-barrel comprising an external jacket (2) and an inner jacket (3), said inner jacket (3) being equipped with a collecting system (11) and an administration system (9), said jacket (3) being joinable to the stopper-plunger (16), piercing it in said piercable baffle (21) and allowing the motion of said plunger inside the container (15), producing the outlet of the fluid contained in it,

said jacket (3) and said stopper-plunger (16), being respectively associated to complementary male part (13) and female part (22) of a coupling system, said coupling system performing a mutual strong coupling when said first and the second element, (14) and (1) respectively, are combined together so that the container (15) can be retracted during use,

said collecting system and said administration system being connected to said inner jacket (3) and comprising a needle (9) ending with a sharp tip (11), said sharp tip being capable of piercing said stopper-plunger (16) through said baffle (21), said tip (11) being surrounded by said male and female coupling system, and not protruding from said second element (1), and in addition, said housing barrel (1) having an open end (10), said male and female coupling system (13) and (22) and said sharp tip (11) being housed inside said housing barrel (1), and being slightly retracted with respect to said open end (10), in order to avoid any contact with the operator, further

said male coupling part (13) being bell-shaped, said complementary female part (22) of said stopper-plunger (16) being provided with a locking lip (23) to firmly block the coupling of said parts (13) and (22), and to avoid easy release of said parts, said external jacket (2) and said inner jacket (3) defining a cavity (4), a sealing device (5) for closing said cavity, said sealing device (5) being provided with an inner joint unit (7),

said inner jacket (3) of said housing barrel (1) is removably fixed to said joint unit (7), thus allowing the after-use recovery and the re-use of that part of said housing-barrel (1) which does not come into contact with the administered fluid, and in addition,

the external jacket (2) is provided with side openings (8), for allowing access in the interior of said housing barrel (1) to remove said inner jacket (3).

2. The device according to claim 1 wherein the first element (14) and said housing barrel (1) are cylindrically shaped and the complementary coupling parts (13) and (22) are placed in axial position with respect to said element (14) and said housing barrel (1).

3. The device according to claim 1 wherein:

said needle (9) is made of steel or plastic, said stopper plunger (16) is made of an elastomeric material selected from the group consisting of bromo- or chlorobutyl rubber whereby high sealing and sliding performance are achieved,

said element (14) being made of glass and said housing barrel (1) being made of plastic material.

4. The device according to claim 3 wherein said plastic material is biodegradable.