Medical multilayer film and containers having plurality of chambers

• US 5,520,975 A
• Filed: 10/04/1994
• Issued: 05/28/1996
• Est. Priority Date: 02/05/1993
• Status: Expired due to Fees

• Current Assignee: Otsuka Pharmaceutical Factory Incorporated (Otsuka Holdings Company Limited)
• Original Assignee: Otsuka Pharmaceutical Factory Incorporated (Otsuka Holdings Company Limited)
• Inventors: Inoue, Fujio, Izumi, Masamitsu, Kashiyama, Shigetoshi
• Primary Examiner(s): Page, Thurman K.
• Assistant Examiner(s): Benston, Jr., William E.
• Application Number:
  US08/313,047
• Time in Patent Office: 602 Days
• Field of Search: 424/400, 424/473, 424/485, 428/35.9, 428/36
• US Class Current: 428/35.9
• CPC Class Codes: A61J 1/10 Bag-type containers
• CPC Class Codes: A61J 1/2024 having peelable seals
• CPC Class Codes: A61J 1/2093 Containers having several compartments for products to be mixed
• CPC Class Codes: B32B 2250/242 All polymers belonging to those covered by group B32B27/32
• CPC Class Codes: B32B 2307/72 Density
• CPC Class Codes: B32B 2439/80 Medical packaging
• CPC Class Codes: B32B 27/08 of synthetic resin
• CPC Class Codes: B32B 27/32 comprising polyolefins comprising vinyl (co)polymers or acrylic (co)polymers B32B27/30
• CPC Class Codes: Y10T 428/1359 Three or more layers [continuous layer]
• CPC Class Codes: Y10T 428/24992 Density or compression of components
• CPC Class Codes: Y10T 428/31909 Next to second addition polymer from unsaturated monomers

Abstract

A medical multilayer film chiefly for use in forming medical containers having a plurality of chambers comprises an inner layer, an intermediate layer and an outer layer each made primarily of a polyolefin, the inner layer being formed of resin mixture of an ethylene-alpha-olefin copolymer having a density of 0.930 to 0.945 g/cm³ and a polypropylene, the intermediate layer including at least one resin mixture layer of resin mixture of an ethylene-alpha-lefin copolymer having a density of 0.920 to 0.945 g/cm³ and an ethylene-alpha-olefin elastomer having a density of 0.880 to 0.890 g/cm³ in a mixing ratio by weight of 1:5 to 2:1, the resin mixture layer having a thickness of at least 85% of the overall thickness of the intermediate layer, the outer layer being formed of an ethylene-alpha-olefin copolymer having a density of 0.930 to 0.945 g/cm³. The film having this structure is excellent in any of heat resistance, transparency, flexibility, impact resistance and easily peelable sealing properties.

Claims

1. A medical multilayer film characterized in that the film comprises an inner layer, an intermediate layer and an outer layer each made primarily of a polyolefin,

the inner layer being formed of resin mixture of an ethylene-alpha-olefin copolymer having a density of 0.930 to 0.945 g/cm³ and a polypropylene,

the intermediate layer including at least one resin mixture layer of resin mixture of an ethylene-alpha-olefin copolymer having a density of 0.920 to 0.945 g/cm³ and an ethylene-alpha-olefin elastomer having a density of 0.880 to 0.890 g/cm³ in a mixing ratio by weight of 1:

5 to 2;

1, the resin mixture layer having a thickness of at least 85% of the overall thickness of the intermediate layer, and

the outer layer being formed of an ethylene-alpha-olefin copolymer having a density of 0.930 to 0.945 g/cm³.

2. A medical multilayer film as defined in claim 1 wherein the ethylene-alpha-olefin copolymer of the intermediate layer has a density of 0.930 to 0.945 g/cm³.

3. A medical multilayer film as defined in claim 1 or 2 wherein the intermediate layer consists singly of the resin mixture layer.

4. A medical multilayer film as defined in claim 1 or 2 wherein the intermediate layer has a multilayer structure comprising the resin mixture layer and other resin layer formed at an intermediate portion of the layer, the other resin layer being made of an ethylene-alpha-olefin copolymer having a density of 0.930 to 0.945 g/cm³.

5. A medical multilayer film as defined in claim 1 wherein the ethylene-alpha-olefin copolymer used in each of the inner layer, the intermediate layer and the outer layer is 0.938 to 0.942 g/cm³ in density.

6. A medical multilayer film as defined in claim 1 wherein the ethylene-alpha-olefin copolymer used in each of the inner layer, the intermediate layer and the outer layer is 0.940 to 0.942 g/cm³ in density.

7. A medical multilayer film as defined in claim 1 or 2 wherein the ethylene-alpha-olefin elastomer used in the intermediate layer is 0.883 to 0.887 g/cm³ in density.

8. A medical multilayer film as defined in claim 1 or 2 wherein the ethylene-alpha-olefin copolymer and the ethylene-alpha-olefin elastomer serving as the components of the resin mixture layer for use in the intermediate layer are in a mixing ratio by weight of 2:

5 to 1;

2.

9. A medical multilayer film as defined in claim 1 or 2 wherein the ethylene-alpha-olefin copolymer and the ethylene-alpha-olefin elastomer serving as the components of the resin mixture layer for use in the intermediate layer are in a mixing ratio by weihgt of 3:

7.

10. A medical multilayer film as defined in claim 4 wherein the intermediate layer has in the middle thereof the other resin layer of an ethylene-alpha-olefin copolymer having a density of 0.938 to 0.942 g/cm³.

11. A medical multilayer film as defined in claim 4 wherein the intermediate layer has in the middle thereof the other resin layer of an ethylene-alpha-olefin copolymer having a density of 0.940 to 0.942 g/cm³.

12. A medical multilayer film as defined in claim 1 or 2 wherein the ethylene-alpha-olefin copolymer and the polypropylene for use in forming the inner layer are in a mixing ratio by weight of 2:

3 to 2;

1.

13. A medical multilayer film as defined in claim 1 wherein the ethylene-alpha-olefin copolymer used for each of the inner layer, the intermediate layer, and the outer layer is 0.940 to 0.942 g/cm³ in density, the ethylene-alpha-olefin elastomer used for the intermediate layer is 0.883 to 0.887 g/cm³ in density, and the ethylene-alpha-olefin copolymer and the ethylene-alpha-olefin elastomer serving as the components of the resin mixture layer for use in the intermediate layer are in a mixing ratio by weight of 3:

7.

14. A medical multilayer film as defined in claim 4 wherein the ethylene-alpha-olefin copolymer for use in each of the inner layer, the intermediate layer, the other layer and other layer to be formed at an intermediate portion of the intermediate layer is 0.940 to 0.942 g/cm³ in density the ethylene-alpha-olefin elastomer for use in the intermediate layer is 0.883 to 0.887 g/cm³ in density, and the ethylene-alpha-olefin copolymer and the ethylene-alpha-olefin elastomer serving as the components of the resin mixture layer for use in the intermediate layer are 3:

7 in mixing ratio by weight.

15. A medical multilayer film as defined in claim 1 or 2 wherein the polypropylene for use in the inner layer is a propylene homopolymer.

16. A medical multilayer film as defined in claim 1 or 2 wherein the polypropylene for use in the inner layer is a copolymer of an alpha-olefin and propylene serving as the main comonomer.

17. A medical container having a plurality of chambers and formed of a medical multilayer film as defined in claim 1 or 2.

18. A medical container having a plurality of chambers and formed of a medical multilayer film as defined in claim 13.

19. A medical container having a plurality of chambers and formed of a medical multilayer film as defined in claim 14.