System for measuring a blood parameter and method therefor

• US 5,522,389 A
• Filed: 07/02/1991
• Issued: 06/04/1996
• Est. Priority Date: 09/28/1990
• Status: Expired due to Fees

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Hewlett-Packard Company (HP Inc.)
• Inventors: Rother, Peter, Fischer, Bernhard
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): NASSER, ROBERT L
• Application Number:
  US07/724,865
• Time in Patent Office: 1,799 Days
• Field of Search: 128/633-4, 128/664-6, 356/41
• US Class Current: 600/324
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence

Abstract

A system for measuring a blood parameter, such as pH, pCO₂ or pO₂, comprises an optical probe with an optical fiber and an invasive blood sensor. Light emitted by a light-emitting diode (1) is irradiated into an optical fiber (2). The system compensates for variations in the luminous efficiency of the LED (1) in that either a fraction of the light is fed directly to a photodetector (22), or in that the forward voltage of the LED is measured, and in that the signal received from the sensor is either normalized, or in that the LED drive current is adjusted accordingly.

Claims

1. A system for measuring a blood parameter such as pH, pCO₂ or pO₂, said system comprising:

an optical probe including a blood sensor and a connected probe optical fiber, said blood sensor including a dye that modifies optical characteristics of light fed from said probe optical fiber, and reflective means for feeding back modified light into said probe optical fiber;

monitor means including light-emitting diode means for radiating a light beam, a first photo detector and a second photo detector;

an excitation optical fiber coupled to said light emitting diode means and terminating in a beam splitting means, said excitation optical fiber having a sufficient length that enables, at said beam splitting means, a uniform distribution thereacross of light emitted from said light emitting diode means, said beam splitting means thereby providing a plurality of split light beams with intensities that are constant with respect to each other;

light fiber means coupling a first said split light beam to said first photodetector and a second said split beam to a coupler that is connected to said probe optical fiber, said light fiber means also coupling light fed back from said blood sensor through said coupler to said second photodetector;

whereby said first photodetector provides a correction signal indicative of said first split light beam'"'"'s intensity and said second photodetector provides a sense signal indicative of said fed back light'"'"'s intensity, said monitor means employing said correction signal to correct said sense signal so as to achieve an accurate measurement of said blood parameter.

2. A system according to claim 1, wherein said monitor means further comprises:

means for normalizing a value derived from said sense signal that is indicative of the intensity of the light fed back from said blood sensor with respect to a value derived from the correction signal, said means employing the equation ##EQU6## wherein I_normalized is the normalized intensity, I_measured is the intensity of the light fed back to said second photodetector, and I_reference is the light intensity measured by said first photodetector.

3. A system according to claim 1, wherein said light emitting diode means comprises at least two light-emitting diodes, or a dual-light emitting diode for emitting light of different wavelengths wherein the light of the first wavelength is modified by the dye in the blood sensor and the light of the second wavelength is substantially not modified thereby.

4. A system according to claim 3, wherein said at least two light-emitting diodes or said dual-light emitting diode are actuated alternately.

5. A system according to claim 3, wherein the light fed back from said optical probe is normalized, said monitor means calculating a normalized intensity by means of the following equation:

##EQU7## wherein I.sub.λ

1,measured is the intensity of light of the first wavelength fed back to said second photodetector, I.sub.λ

2,measured is the intensity of the light of the second wavelength fed back to said second photodetector, I.sub.λ

1,reference is the intensity of light of the first wavelength measured by said first photodetector, and I.sub.λ

2,reference is the intensity of light of the second wavelength measured by said first photodetector.