Skin treatment composition

• US 5,523,090 A
• Filed: 02/24/1995
• Issued: 06/04/1996
• Est. Priority Date: 02/24/1995
• Status: Expired due to Term

• Current Assignee: Chesebrough-Pond'S Usa Co., Division Of Conopco, Inc.
• Original Assignee: Chesebrough-Pond'S Usa Co., Division Of Conopco, Inc.
• Inventors: Cheney, Michael C., Znaiden, Alexander P., Slavtcheff, Craig S.
• Primary Examiner(s): VENKAT, JYOTHSNA A
• Application Number:
  US08/393,979
• Time in Patent Office: 466 Days
• Field of Search: 424/401, 514/860, 514/846, 514/944
• US Class Current: 424/401
• CPC Class Codes: A61K 8/365 Hydroxycarboxylic acids; Ketocarboxylic acids
• CPC Class Codes: A61K 8/4953 containing pyrimidine ring derivatives, e.g. minoxidil
• CPC Class Codes: A61K 8/55 Phosphorus compounds
• CPC Class Codes: A61Q 19/06 for countering cellulitis

Abstract

Skin treatment compositions for improving skin strength and firmness and reducing signs of cellulite. The compositions contain a xanthine (e.g., caffeine or theophylline) and an inositol phosphoric acid, and/or alpha hydroxy acid. The ratio of the xanthine to the acid is in a specific range to maintain the xanthine in a solubilized state. A method of preventing or reducing the signs of cellulite by applying a mixture of an inositol phosphoric acid and an alpha hydroxy acid is also disclosed.

Claims

1. A skin treatment composition comprising:

(i) a xanthine in an amount of from about 0.05% to about 20% wherein the xanthine is selected from the group consisting of caffeine, theophylline and mixtures thereof;

(ii) phytic acid, wherein the weight ratio of xanthine to the acid is from about 2;

1 to about 0.001;

1; and

(iii) a cosmetically acceptable vehicle.

2. The composition of claim 1 wherein the pH of the composition is less than or equal to 5.5.

3. The composition of claim 1 wherein the pH of the composition is in the range of from 1.5 to 5.5.

4. The composition of claim 1 wherein the xanthine is present in the amount of at least 0.5%.

5. A method of treating the appearance of flaccid skin or the appearance of cellulite, the method comprising applying topically to skin the composition of claim 1.

6. A skin treatment composition comprising:

(i) a xanthine in an amount of from about 0.05% to about 20%, wherein the xanthine is selected from the group consisting of caffeine, theophylline and mixtures thereof;

(ii) an alpha hydroxy acid, wherein the weight ratio of xanthine to the acid is from about 2;

1 to about 0.001;

1, wherein the α

-hydroxy acid is selected from the group consisting of lactic acid, glycolic acid and mixtures thereof; and

(iii) a cosmetically acceptable vehicle.

7. The composition of claim 6 wherein the pH of the composition is less than or equal to 5.5.

8. The composition of claim 6 wherein the pH of the composition is in the range of from 1.5 to 5.5.

9. The composition of claim 6 wherein the xanthine is present in the amount of at least 0.5%.

10. The composition of claim 6 further comprising phytic acid.

11. A method of treating the appearance of flaccid skin or cellulite, the method comprising applying topically to skin the composition of claim 6.