Isolated layer pulse oximetry

• US 5,524,617 A
• Filed: 03/14/1995
• Issued: 06/11/1996
• Est. Priority Date: 03/14/1995
• Status: Expired due to Term

• Current Assignee: Nellcor Incorporated (Medtronic Plc)
• Original Assignee: Nellcor Incorporated (Medtronic Plc)
• Inventors: Mannheimer, Paul D.
• Primary Examiner(s): Sykes, Angela D.
• Assistant Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US08/403,642
• Time in Patent Office: 455 Days
• Field of Search: 128/633, 128/664, 128/665, 356/41
• US Class Current: 600/323
• CPC Class Codes: A61B 2562/0242 for varying or adjusting the optical path length in the tissue
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: G01N 21/314 with comparison of measurements at specific and non-specific wavelengths dual wavelength spectrometry G01J3/427
• CPC Class Codes: G01N 21/49 within a body or fluid

Abstract

An apparatus of and method for measuring arterial blood oxygen saturation at a particular tissue level of interest. Visible and near infrared radiation are emitted into a patient at the measurement site using two different wavelengths. Detection at two different detection sites permits rejection of oxygen saturation at undesired tissue levels.

Claims

1. A pulse oximeter apparatus for calculating arterial oxygen saturation, comprising:

a. a patient interface means for coupling to a patient and including at least three electromagnetic elements wherein at least one of the electromagnetic elements is an electromagnetic emitter for emitting electromagnetic radiation into a tissue of the patient and at least one of the elements is an electromagnetic detector for detecting the electromagnetic radiation that is reflected from the tissue, a first spacing being between a first combination of two of the three electromagnetic elements providing a first path length of said first combination, a second spacing being between a second combination of two of the three electromagnetic elements providing a second path length of said second combination, the first path length being different from the second path length; and

b. means for calculating an arterial oxygen saturation level of the patient in response to the detected electromagnetic radiation;

the calculating means utilizing an algorithm that filters out pulsatile signal contributions of a surface tissue layer of the patient so as to yield an arterial oxygen saturation value indicative of that of a tissue layer below the patient'"'"'s surface tissue layer.

2. The apparatus of claim 1, further comprising more than three electromagnetic elements arrayed on the patient interface means.

3. The apparatus of claim 1 in which the at least three electromagnetic elements comprise first and second separated and spaced apart emitters each capable of generating light of at least two distinct wavelengths, and a detector, the first emitter and the detector corresponding to the first combination of electromagnetic elements, the second emitter and the detector corresponding to the second combination of electromagnetic elements.

4. The apparatus of claim 1 in which the at least three electromagnetic elements comprise first and second detectors each capable of detecting light of at least two different wavelengths, and an emitter element capable of generating light at the at least two different wavelengths, the emitter and the first detector corresponding to the first combination of electromagnetic elements, the emitter and the second detector corresponding to the second combination of electromagnetic elements.

5. A method of measuring oxygen saturation level of arterial blood at a measurement site of a patient comprising:

a. determining a time of arrival of an arterial pulse wavefront at the measurement site of the patient;

b. emitting a first wavelength of electromagnetic radiation at the measurement site of the patient;

c. measuring an amplitude of the first wavelength of electromagnetic radiation at a first detector located at a first distance from the measurement site;

d. measuring an amplitude of the first wavelength of electromagnetic radiation at a second detector located at a second distance from the measurement site;

e. a second wavelength of electromagnetic radiation at the measurement site of the patient;

f. measuring an amplitude of the second wavelength of electromagnetic radiation at the first detector located at the first distance from the measurement site;

g. measuring an amplitude of the second wavelength amplitude of electromagnetic radiation at the second detector located at the second distance from the measurement site;

h. computing an arterial oxygen saturation level, at a predetermined tissue level of interest with an algorithm that filters out pulsatile signal contributions from a second predetermined tissue level using the amplitudes of said first wavelength measured at the first detector and the second detector and using the amplitudes of said second wavelength measured at the first detector and the second detector.

6. A method according to claim 5 wherein said first distance and said second distance are selected to optimize measurement at said predetermined tissue level of interest.

7. A pulse oximeter apparatus for calculating arterial oxygen saturation, comprising:

a. a patient interface means for coupling to a patient and including at least three electromagnetic elements wherein at least one of the electromagnetic elements is an electromagnetic emitter for emitting electromagnetic radiation into a tissue of the patient and at least one of the elements is an electromagnetic detector for detecting the electromagnetic radiation that is reflected from the tissue, a first spacing being between a first combination of two of the three electromagnetic elements providing a first path length of said first combination, a second spacing being between a second combination of two of the three electromagnetic elements providing a second path length of said second combination, the first path length being different from the second path length; and

b. means for calculating an arterial oxygen saturation level of the patient in response to the detected electromagnetic radiation;

the calculating means using an algorithm that filters out arterial pulsatile signals contributed by a tissue layer beneath a surface tissue layer of the patient so as to yield an arterial oxygen saturation value indicative of that which exists in the patient'"'"'s surface tissue layer.

8. The apparatus of claim 7, further comprising more than three electromagnetic elements arrayed on the patient interface means.

9. The apparatus of claim 7 in which the at least three electromagnetic elements comprise first and second separated and spaced apart emitters each capable of generating light of at least two distinct wavelengths, and a detector, the first emitter and the detector corresponding to the first combination of electromagnetic elements, the second emitter and the detector corresponding to the second combination of electromagnetic elements.

10. The apparatus of claim 7 in which the at least three electromagnetic elements comprise first and second detectors each capable of detecting light of at least two different wavelengths, and an emitter element capable of generating light at the at least two different wavelengths, the emitter and the first detector corresponding to the first combination of electromagnetic elements, the emitter and the second detector corresponding to the second combination of electromagnetic elements.