Mixing and delivery syringe assembly
First Claim
1. A device for intermixing a first component with a second component and for dispensing the mixture from the device comprising:
- (a) a housing having first and second end portions, and an internal chamber with an outlet;
(b) container means connected to said second end portion of said housing containing a first component, said container means being movable relative to said chamber from a first position to a second position;
(c) adding means disposed within said internal chamber for adding a second component to said first component to form an infusible mixture upon movement of said container means toward said second position, said adding means comprising a scaffold upon which said second component is removably carried in a manner such that said second component will be presented to said first component for removal thereby from said scaffold upon movement of said container means toward said second position;
(d) valve means for controlling the flow of said first component from said container means toward said adding means; and
(e) flow means for permitting fluid flow between said adding means and said outlet of said internal chamber upon movement of said container means toward said second position.
6 Assignments
0 Petitions
Accused Products
Abstract
A device for intermixing a first component, such as a parenteral fluid with a second component, such as an immobilized drug carried by a scaffold to form a beneficial agent which, following the mixing step, can be dispensed directly from the device for infusion into a patient. The device includes novel mechanisms for mateably interconnecting a container, such as a glass vial containing the first component with a housing having a fluid outlet which houses a sealed container containing the second component, and then for controllably mixing the components under sterile conditions to form an injectable solution which is automatically dispensed through the fluid outlet of the device.
207 Citations
38 Claims
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1. A device for intermixing a first component with a second component and for dispensing the mixture from the device comprising:
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(a) a housing having first and second end portions, and an internal chamber with an outlet; (b) container means connected to said second end portion of said housing containing a first component, said container means being movable relative to said chamber from a first position to a second position; (c) adding means disposed within said internal chamber for adding a second component to said first component to form an infusible mixture upon movement of said container means toward said second position, said adding means comprising a scaffold upon which said second component is removably carried in a manner such that said second component will be presented to said first component for removal thereby from said scaffold upon movement of said container means toward said second position; (d) valve means for controlling the flow of said first component from said container means toward said adding means; and (e) flow means for permitting fluid flow between said adding means and said outlet of said internal chamber upon movement of said container means toward said second position. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A device for intermixing a first component with a second component to form an infusible mixture and for dispensing the infusible mixture from the device into the environment of use, said device comprising:
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(a) a hollow housing having an internal chamber and first and second ends; (b) a closure cap connected to said first end of said hollow housing, said cap having a passageway in communication with said internal chamber of said hollow housing; (c) container means connected to said second end of said hollow housing for telescopic movement relative said internal chamber from a first position to a second position, a container means containing said first component; (d) adding means removably receivable within said internal chamber of said hollow housing for adding a second component to said first component to form an infusible mixture upon movement of said container means toward said second position, said adding means comprising a scaffold upon which said second component is removably affixed so that said second component will be presented to said first component for removal from said scaffold upon movement of said container means relative to said internal chamber; (e) first means for controlling the passage of said first component toward said adding means; and (f) second means for controlling the passage of said infusible mixture between said adding means and said passage of said closure cap upon movement of said container means toward said second position. - View Dependent Claims (9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A device for intermixing a first component with a second component to form an infusible mixture and for dispensing the infusible mixture from the device into the environment of use, said device comprising:
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(a) a hollow housing having an internal chamber and first and second ends; (b) a closure cap connected to said first end of said hollow housing, said cap having a passageway in communication with said internal chamber of said hollow housing; (c) container means connected to said second end of said hollow housing for telescopic movement relative said internal chamber from a first position to a second position, said container means containing a first component; (d) adding means removably receivable within said internal chamber of said hollow housing for adding a second component to said first component to form infusible mixture upon movement of said container means toward said second position, said adding means comprising a vial having a chamber and a scaffold disposed within said chamber said second component being removably affixed to said scaffold for removal therefrom as said first component flows proximate said scaffold due to movement of said container means toward said second position; (e) first means for controlling the passage of said first component toward said adding means said first means comprising valve means disposed within said container for controlling the passage of said first component toward said adding means; and (f) second means for controlling the passage of said infusible mixture between said adding means and said passage of said closure cap upon movement of said container means toward said second position, said second means comprising; (i) an outlet valve means disposed within said vial; and (ii) a valve operating means disposed within said cap for operating said outlet valve means. - View Dependent Claims (21, 22, 23, 24)
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25. A device for intermixing a first component with a second component to form an infusible mixture and for dispensing the infusible mixture from the device into the environment of use, said device comprising:
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(a) a hollow housing having an internal chamber and first and second ends; (b) a closure cap connected to said first end of said hollow housing, said cap having a passageway in communication with said internal chamber of said hollow housing; (c) container means connected to said second end of said hollow housing for telescopic movement relative said internal chamber from a first position to a second position, said container means comprising a container having an internal wall, containing said first component, said container means further comprising container barrier means formed on said internal wall for providing a barrier to the passage of gases; (d) adding means removably receivable within said internal chamber of said hollow housing for adding a second component to said first component to form an infusible mixture upon movement of said container means toward said second position, said adding means comprising a vial having an external wall and an internal wall defining a chamber and a scaffold disposed within said chamber upon which said second component is removably affixed, for removal therefrom as said first component flows proximate said scaffold due to movement of said container means toward said second position said adding means further including vial barrier means formed on said internal wall for controlling the transport of water and gases; (e) first means for controlling the passage of said first component toward said adding means; and (f) second means for controlling the passage of said infusible mixture between said adding means and said passage of said closure cap upon movement of said container means toward said second position. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38)
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Specification