Acyclic purine phosphonate nucleotide analogs as antiviral agents, and related synthetic methods
First Claim
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1. A compound having the structural formula (VIIIb) ##STR17## in enantiomerically pure form.
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Abstract
Acyclic purine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. These antiviral agents have the structural formula (Ia) or (Ib) ##STR1## and may be in acid, salt or ester form. Such compounds may also be dehydrated to provide antiviral agents in cyclic form. Pharmaceutical compositions are provided containing the antiviral agents, as is a chiral synthesis which may be used to prepare the agents in enantiomerically pure form or as a racemic mixture.
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3 Claims
- 1. A compound having the structural formula (VIIIb) ##STR17## in enantiomerically pure form.
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