Method and apparatus for blood chemistry analysis
First Claim
1. A method of analyzing a patients blood, the blood having a plurality of analytes, each of the analytes having a characteristic electrical charge and being composed of a plurality of identical molecules, each molecule carrying a unit of the charge, the concentration of the analyte being defined by the number of molecules present within a unit volume of the blood, the method comprising the steps of:
- (a) attaching a plurality of electrodes to the patient;
(b) detecting the characteristic charge of an analyte present in the patient'"'"'s blood;
(c) transmitting an electrical signal proportional to the characteristic charge to an isotonic bath wherein said signal causes the anions and cations present in the bath to separate thereby creating a reactive solution, wherein the amount of separation is proportional to the magnitude of the signal;
(d) mixing a reagent with the reactive solution to form a test solution;
(e) analyzing the test solution; and
(f) displaying the analysis results.
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Accused Products
Abstract
A blood chemistry analyzer for determining the concentration of various chemical compounds or analytes in a patient'"'"'s blood in a non-invasive manner employs a plurality of electrodes, an isotonic bath, a spectrophotometer, and a control unit. Adhesive electrodes are attached to the patient'"'"'s skin such that the patient'"'"'s entire peripheral blood supply system is analyzed. The controller provides a signal to the electrodes that causes the electrodes to develop an electrical charge, or potential, having a magnitude proportional to the detected charge for the analyte of interest. This potential is transmitted to an isotonic bath where it causes a portion of the dissolved salts to separate into anions and cations. The amount of separation is proportional to the magnitude of the electrical potential. Predetermined volumes of the anion/cation saturated isotonic solution are piped into reagent wells containing a reagent corresponding to the specific blood analyte of interest. The test solution is transported to a spectrophotometer where it is analyzed by known methods. The spectrophotometer transmits digitized test data to a microprocessor located in the control unit. The microprocessor performs calculations on these digital values according to algorithms stored in the microprocessor storage unit.
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Citations
14 Claims
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1. A method of analyzing a patients blood, the blood having a plurality of analytes, each of the analytes having a characteristic electrical charge and being composed of a plurality of identical molecules, each molecule carrying a unit of the charge, the concentration of the analyte being defined by the number of molecules present within a unit volume of the blood, the method comprising the steps of:
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(a) attaching a plurality of electrodes to the patient; (b) detecting the characteristic charge of an analyte present in the patient'"'"'s blood; (c) transmitting an electrical signal proportional to the characteristic charge to an isotonic bath wherein said signal causes the anions and cations present in the bath to separate thereby creating a reactive solution, wherein the amount of separation is proportional to the magnitude of the signal; (d) mixing a reagent with the reactive solution to form a test solution; (e) analyzing the test solution; and (f) displaying the analysis results. - View Dependent Claims (2, 3, 4, 5)
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6. A chemistry analyzer for analyzing a patient'"'"'s blood, the blood having a plurality of analytes, each of the analytes having a characteristic electrical charge and being composed of a plurality of identical molecules, each molecule carrying a unit of the charge, the concentration of the analyte being defined by the number of molecules present within a unit volume of the blood, the analyzer comprising:
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detector means, said detector means comprising a plurality of electrodes, each of said electrodes being mountable on the patient and comprising means for detecting units of at least one characteristic electrical charge and transmitting a signal having a magnitude proportional to the number units of charge detected; isotonic bath means comprising a pair of electrodes defining an anode and a cathode and a first solution composed of water and at least one salt, said electrodes being in electrical communication with said detector means for receiving said signal wherein said signal applies an electrical potential to said electrodes, the electrical potential having a magnitude proportional to said magnitude of said signal, whereby said electrical potential causes said salt to separate into a number of anions and cations thereby defining a second solution, said number of cations and anions being proportional to said magnitude of said electrical potential; means for analyzing a portion of said second solution wherein said analyzer means determines the concentration of the analyte within the patient'"'"'s blood. - View Dependent Claims (7, 8, 9, 10, 11)
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12. A chemistry analyzer for analyzing a patient'"'"'s blood, the blood having a plurality of analytes, each of the analytes having a characteristic electrical charge and being composed of a plurality of identical molecules, each molecule carrying a unit of the charge, the concentration of the analyte being defined by the number of molecules present within a unit volume of the blood, the analyzer comprising:
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detector means, said detector means comprising a plurality of electrodes, each of said electrodes being mountable on the patient and comprising means for detecting units of at least one characteristic electrical charge and transmitting a signal having a magnitude proportional to the number units of charge detected; isotonic bath means comprising a pair of electrodes defining an anode and a cathode and a first solution composed of water and at least one salt, said electrodes being in electrical communication with said detector means for receiving said signal wherein said signal applies an electrical potential to said electrodes, the electrical potential having a magnitude proportional to said magnitude of said signal, whereby said electrical potential causes said salt to separate into a number of anions and cations thereby defining a second solution, said number of cations and anions being proportional to said magnitude of said electrical potential; means for analyzing a portion of said second solution wherein said analyzer means determines the concentration of the analyte within the patient'"'"'s blood, said analyzer means comprising a spectrophotometer having container means for receiving a reagent and a portion of said second solution, said reagent and said portion defining a third solution, said spectrophotometer comprising measurement means for measuring the optical absorbance of said third solution and signal means for providing a signal proportional to said optical absorbance. - View Dependent Claims (13, 14)
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Specification