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Hemofiltration and plasmafiltration devices and methods

  • US 5,536,412 A
  • Filed: 01/11/1994
  • Issued: 07/16/1996
  • Est. Priority Date: 02/06/1992
  • Status: Expired due to Term
First Claim
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1. A filtration process for removing blood toxins, comprising:

  • passing a fluid containing protein bound and/or middle molecular weight blood toxins through the interior of a hollow fiber membrane;

    during said passing, circulating a sorbent suspension against exterior surfaces of the hollow fiber membrane;

    during said passing and circulating, applying intermittent pulses of positive pressure to said sorbent suspension so that the fluid or a fraction thereof alternately exits and re-enters the interior of the hollow fiber membrane, wherein said fluid or fraction which exits the interior of the hollow fiber membrane contains the protein bound and/or middle molecular weight toxins which contact said sorbent suspension so as to effectuate removal of said toxins from said fluid and delivery of said toxins into said sorbent suspension.

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