Radioactive beam irradiation method and apparatus taking movement of the irradiation area into consideration

• US 5,538,494 A
• Filed: 03/17/1995
• Issued: 07/23/1996
• Est. Priority Date: 03/17/1994
• Status: Expired due to Term

• Current Assignee: Hitachi, Ltd.
• Original Assignee: Hitachi, Ltd.
• Inventors: Matsuda, Koji
• Primary Examiner(s): Berman, Jack I.
• Application Number:
  US08/405,858
• Time in Patent Office: 494 Days
• Field of Search: 250/492.3, 378/65, 128/395 R, 128/396, 128/714, 128/721, 600/1, 600/2
• US Class Current: 600/1
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: A61B 6/541 involving acquisition triggered by a physiological signal
• CPC Class Codes: A61B 8/13 Tomography A61B8/10, A61B8/12 take precedence; tomography for radiation diagnosis A61B6/02
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/1048 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: A61N 5/1064 for adjusting radiation treatment in response to monitoring
• CPC Class Codes: A61N 5/1068 Gating the beam as a function of a physiological signal
• CPC Class Codes: G21K 5/04 with beam-forming means

Abstract

A radiation irradiation method and an apparatus enables effective radiation irradiation even in the case of a diseased part changing its position due to physical activity, such as breathing and the heart beat of the patient, with a simplified apparatus. Initially, the position change of the diseased part and the physical activity of the patient are measured concurrently, and a relationship therebetween is defined as a corresponding function. Next, along with the detection of the physical activity of the patient, radiation therapy is performed, in which the control of the radiation irradiation is carried out in accordance with the corresponding function.

Claims

1. A radiation irradiation method, comprising the steps of:

detecting a signal representing a physical activity of a patient having a diseased area to be irradiated with radiation, said physical activity being an activity which causes periodic movement of the diseased area, and

controlling a timing of radiation irradiation of said diseased area so that said irradiation is synchronized with said detected signal.

2. The radiation irradiation method defined in claim 1, wherein:

a relation between a time change of said physical activity of the patient as indicated by said detected signal and a position change of the diseased area is obtained, and

radiation is activated when said position change of the diseased position becomes a minimum.

3. A radiation irradiation apparatus, comprising:

a detector for measuring a time change of a physical activity of a patient having a diseased area to be irradiated with radiation, said physical activity being an activity which causes periodic movement of the diseased area;

an information processing apparatus, connected to a memory apparatus for storing a relation between a detected signal from said detector indicating a time change of physical activity of the patient and a position change of said diseased area, for determining a radiation irradiation timing based on said detected signal from said detector and information from said memory means; and

radiation control means for controlling timing of irradiation of said diseased area in response to an output signal from said information processing apparatus.

4. A radiation irradiation apparatus, comprising:

a particle accelerator for accelerating a charged particle; and

an irradiation apparatus for irradiating said accelerated charged particle from said particle accelerator on a specified area of a patient;

a display apparatus for displaying an operation state of said particle accelerator; and

a display apparatus for displaying a time change of physical activity of said patient, said physical activity being an activity which causes periodic movement of said specified area which said charged particle is irradiated.

5. A particle beam irradiation apparatus, comprising:

a particle accelerator for repeating periodically an operation sequence for injection, acceleration and ejection of a particle;

an irradiation apparatus for irradiating said accelerated particle on a specified area of a patient; and

means for initiating said operation sequence of said particle accelerator at a designated timing in response to the breathing of said patient.

6. The particle beam irradiation apparatus defined in claim 5, wherein:

a particle beam is irradiated on said specified area once every time said patient takes a breath.

7. The particle beam irradiation apparatus defined in claim 5, wherein:

said designated timing of breathing of the patient is synchronized with either or both of a start of beam ejection and a termination of beam ejection of said particle accelerator.

8. The particle beam irradiation apparatus defined in claim 6, wherein:

said charged particle is injected and accelerated from a time when the patient starts breathing-in to a time when the patient terminates breathing-out, and

said charged particle is ejected from a time when the patient terminates breathing-out to a time when the patient next starts breathing-in.

9. The particle beam irradiation apparatus defined in claim 6, wherein:

said charged particle is injected and accelerated from a time when the patient starts breathing-out to a time when the patient next terminates breathing-in, and

said charged particle is ejected from a time when the patient terminates breathing-in to a time when the patient next starts breathing-out.