Intra-extravascular drug delivery catheter and method
First Claim
1. A method of treating a vessel having a vessel wall with an inner surface, the method comprising the steps of:
- inserting a catheter having a vessel puncturing element disposed therein into a substantially tubular vessel;
positioning the puncturing element at the site in the vessel to be treated;
restraining said puncturing element such that it is maintained in a retracted position;
placing said puncturing element in a puncturing position in which said puncturing element is no longer restrained;
said puncturing element automatically moving in a direction substantially non-parallel with respect to a portion of said catheter that contains said puncturing element when said puncturing element is no longer being restrained.
2 Assignments
0 Petitions
Accused Products
Abstract
A drug delivery catheter is provided which includes a catheter comprised of an elongated tubular shaft with an inner lumen and a vessel puncturing element which is housed in the lumen. The puncturing element has a retracted position such that it will not be in contact with the vessel wall as the catheter is guided through the vasculature. The puncturing element also has a puncturing position where it protrudes radially outward of the catheter shaft and engages and punctures the vessel wall. The catheter is first inserted into the vessel to be treated and the puncturing element is positioned at the site in the vessel to be treated. The puncturing element is then moved to its puncturing position and the inner surface of the vessel wall is punctured. A drug is then delivered through the puncture. The drug may be delivered into either the vessel wall itself or to the outside of the vessel wall.
196 Citations
56 Claims
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1. A method of treating a vessel having a vessel wall with an inner surface, the method comprising the steps of:
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inserting a catheter having a vessel puncturing element disposed therein into a substantially tubular vessel; positioning the puncturing element at the site in the vessel to be treated; restraining said puncturing element such that it is maintained in a retracted position; placing said puncturing element in a puncturing position in which said puncturing element is no longer restrained; said puncturing element automatically moving in a direction substantially non-parallel with respect to a portion of said catheter that contains said puncturing element when said puncturing element is no longer being restrained. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method of treating a vessel having a vessel wall with an inner surface, the method comprising the steps of:
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inserting a catheter having a vessel puncturing element disposed therein into a substantially tubular vessel; positioning the puncturing element at the site in the vessel to be treated; inflating an inflatable compartment adjacent said puncturing element to thereby apply an adjacent force adjacent said puncturing element to move said puncturing element in a direction substantially non-parallel with respect to a portion of said catheter that contains said puncturing element, said adjacent force moving said puncturing element from a retracted position to a puncturing position. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24, 25)
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26. A drug delivery device for treating a vessel having a vessel wall with an inner surface, the device comprising:
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an elongated catheter adapted to be inserted into the vessel; said catheter comprising a puncturing element having a retracted position in which said puncturing element does not puncture said vessel wall, at least a portion of said puncturing element being housed in a portion of said catheter when said puncturing element is in said retracted position; a restraint that contacts and holds said puncturing element in said retracted position; said puncturing element further having a puncturing position in which said puncturing element engages and punctures said vessel wall, said puncturing element being substantially non-parallel with respect to said portion of said catheter when said puncturing element is in said puncturing position; said puncturing element automatically moving from said retracted position to said puncturing position when said restraint is no longer being applied; and delivery means coupled to said catheter and delivering a drug through a puncture in the vessel wall. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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38. A drug delivery device for treating a vessel having a vessel wall with an inner surface, the device comprising:
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an elongated catheter adapted to be inserted into the vessel; said catheter comprising a puncturing element having a retracted position in which said puncturing element does not puncture said vessel wall, at least a portion of said puncturing element being housed in a portion of said catheter when said puncturing element is in said retracted position; said puncturing element further having a puncturing position in which said puncturing element engages and punctures said vessel wall, said puncturing element being substantially non-parallel with respect to said portion of said catheter when said puncturing element is in said puncturing position; a movable surface comprising an inflatable compartment coupled to said catheter and adjacent said puncturing element to contact and move said puncturing element from said retracted position to said puncturing position when said movable surface is moved toward said puncturing element. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56)
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Specification