Active substance-containing plaster for the controlled administration of active substances to the skin
First Claim
1. An active substance-containing plaster for the controlled administration of one or more active substances to the skin, comprising a back side and a skin side;
- wherein on the back side is a back layer;
wherein on the skin side is an adhesive means and at least two active substance release surfaces;
wherein a first reservoir for a first active substance is in contact with a peel-off layer which is in contact with the back layer on the back side, and forms a first active substance release surface on the skin side;
wherein a second reservoir for a second active substance is in contact with the peel-off layer on the back side, and forms a second active substance release surface on the skin side;
wherein a reservoir separating layer comprising a gap or space between the first and second active substance reservoir or an inert separating material is present between the first and second active substance reservoir to prevent mixing of the first and second active substances;
wherein the second active substance reservoir is detachable by peeling away, the peel-off layer to terminate administration of its active substance through the second active substance release surface;
wherein the first active substance reservoir remains attached to the skin to further administer its active substance; and
wherein the first active substance release surface has a better adhesion to the skin than to the peel-off layer.
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Accused Products
Abstract
The invention relates to an active substance-containing plaster for the controlled administration of active substances to the skin, which has a back and a skin side, with a back layer, an active substance reservoir divided substantially perpendicularly to the skin contact surface of the plaster and having one or more active substances, a contact adhesive device on the skin side and optionally a cover layer detachable prior to the application of the plaster, whereas at least one active substance reservoir part (12) is detachable from the skin, while leaving behind one or more active substance reservoir parts (13) on the skin. For this object there is provided that the part of the active substance reservoir remaining on the skin is having a better adhesion to the skin than to the back layer (11).
73 Citations
30 Claims
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1. An active substance-containing plaster for the controlled administration of one or more active substances to the skin, comprising a back side and a skin side;
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wherein on the back side is a back layer; wherein on the skin side is an adhesive means and at least two active substance release surfaces; wherein a first reservoir for a first active substance is in contact with a peel-off layer which is in contact with the back layer on the back side, and forms a first active substance release surface on the skin side; wherein a second reservoir for a second active substance is in contact with the peel-off layer on the back side, and forms a second active substance release surface on the skin side; wherein a reservoir separating layer comprising a gap or space between the first and second active substance reservoir or an inert separating material is present between the first and second active substance reservoir to prevent mixing of the first and second active substances; wherein the second active substance reservoir is detachable by peeling away, the peel-off layer to terminate administration of its active substance through the second active substance release surface; wherein the first active substance reservoir remains attached to the skin to further administer its active substance; and wherein the first active substance release surface has a better adhesion to the skin than to the peel-off layer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 18, 19, 21, 23, 24)
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17. An active substance-containing plaster for the controlled administration of one or more active substances to the skin, comprising a back side and a skin side;
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wherein on the back side is a back layer; wherein on the skin side is an adhesive means and at least two active substance release surfaces; wherein a first active substance reservoir is in contact with a peel-off layer which is in contact with an adhesive layer which is between the peel-off layer and the back layer on the back side, and forms a first active substance release surface on the skin side; wherein a second active substance reservoir is in contact with the peel-off layer on the back side, and forms a second active substance release surface on the skin side; wherein a reservoir separating layer comprising a gap or space between the first and second active substance reservoir or an inert separating material is present between the first and second active substance reservoir to prevent mixing of the first and second active substances; wherein the second active substance reservoir is detachable by peeling away, the peel-off layer to terminate administration of its active substance through the second active substance release surface; wherein the first active substance reservoir remains attached to the skin to further administer its active substance; and wherein the first active substance release surface has a better adhesion to the skin than to the peel-off layer. - View Dependent Claims (20, 22, 25, 26, 27, 28, 29, 30)
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Specification